We examined the association between self-reported consumption of fruits and vegetables and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC). Data on ...food consumption and complete follow-up for cancer incidence were available for 130544 men in 7 countries recruited into EPIC between 1993 and 1999. After an average of 4.8 years of follow-up, there were 1104 incident cases of prostate cancer. The associations of consumption of total fruits, total vegetables, cruciferous vegetables and combined total fruits and vegetables with prostate cancer risk were examined using Cox regression, stratified for recruitment center and adjusted for height, weight and energy intake. There was a wide range in consumption of fruits and vegetables: mean intakes (g/day) in the bottom and top fifths of the distribution, as estimated from 24-hr recalls in a subsample of participants, were 53.2 and 410.7 for fruits, 97.1 and 242.1 for vegetables and 169.0 and 633.7 for fruits and vegetables combined. No significant associations between fruit and vegetable consumption and prostate cancer risk were observed. Relative risks (95% confidence intervals) in the top fifth of the distribution of consumption, compared to the bottom fifth, were 1.06 (0.84-1.34) for total fruits, 1.00 (0.81-1.22) for total vegetables and 1.00 (0.79-1.26) for total fruits and vegetables combined; intake of cruciferous vegetables was not associated with risk. These results suggest that total consumption of fruits and vegetables is not associated with the risk for prostate cancer.
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Soybean leghemoglobin a is a small (16 kDa) protein facilitating the transport of O2 to respiring N2‐fixing bacteria at low free‐O2 tension. The crystal structure of soybean ferric leghemoglobin a ...nicotinate has been refined at 2.3 Å resolution. The final R factor is 15.8% for 6877 reflections between 6.0 and 2.3 Å. The structure of soybean leghemoglobin a (143 residues) is closely similar to that of lupin leghemoglobin II (153 residues), the proteins having 82 identical residues when the sequences are aligned. The new structure provides support for the conclusion that the unique properties of leghemoglobin arise principally from a heme pocket considerably larger and more flexible than that of myoglobin, a strongly ruffled heme group, and a proximal histidine orientation more favourable to ligand binding.
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In suggesting that an increase in milk consumption could make an important contribution to reducing rates of osteoporotic fracture the authors overlook the lessons of ecological studies, which link a ...diet high in animal protein to an increased incidence of hip fracture in women. 5 Adding milk to the adolescent diet may be an effective way of increasing calcium intake, but it may not be the best means of preventing osteoporosis in later life. ...there may be a common variable effect. 2 To avoid these related problems, we compared the slope of the regression lines of bone mass against time, and these differed significantly (for example, gain per day in bone mineral content was 770 mg/day for milk group and 690 mg/day for controls).
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Ethics and Politics Nixon, H. C.
Public Administration Review,
10/1952, Volume:
12, Issue:
4
Book Review, Journal Article
Peer reviewed
"Morality in American Politics," by George A. Graham; "Morality and Administration in Democratic Government," by Paul H. Appleby; "Ethics for Policy Decisions," by Wayne A. R. Leys; "Ethical ...Standards in American Public Life," Clarence N. Callender and James C. Charlesworth, eds.; "Ethical Standards in Government," Report of a Subcommittee of the Committee on Labor and Public Welfare, U. S. Senate
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178.
REVIEWS HUTCHINSON, GILLIAN; SCAMMELL, GEOFFREY; APPLEBY, JOHN ...
The Mariner's Mirror,
19/1/1/, Volume:
79, Issue:
2
Book Review
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