From July 1980, 104 consecutive patients with previously untreated small-cell lung cancer (SCLC) received vincristine 1.4 mg/m2, doxorubicin (Adriamycin) 40 mg/m2, and Etoposide (VePesid) 300 mg/m2 ...intravenously (as a single infusion) every 3 weeks. The overall response rate (complete response plus partial response) was 58%. In 47 patients with limited disease the response rate was 66% with 21/47 (45%) complete responders. Treatment was delivered on an outpatient basis. Toxicity was mild, and in 455 rapid infusions of etoposide, there have been no adverse reactions.
The development of quantitative techniques to assist in the analysis of planar thallium-201 stress-redistribution scintigrams has led to improved abilities of this modality to detect the presence of ...and to localize significant coronary artery disease (CAD). This fact has encouraged the reevaluation of its capabilities relative to other types of scintigraphic data collection, including seven-pinhole tomography. We have undertaken a comparison of planar scintigraphy and seven-pinhole tomography to detect in 40 exercised patients (23 with angiographically demonstrated CAD, eight with normal coronary angiograms, and nine with less than or equal to 1% likelihood of having CAD) the presence of significant CAD and to localize it correctly to an individual coronary artery. Emphasis was placed on similar imaging conditions and on analysis of images by the same quantitative program of TI-201 distribution and washout. Both techniques were found to be highly sensitive and specific for disease detection and localization. Importantly, seven-pinhole tomography did not significantly improve results.
Book reviews O'Riordan, Timothy; Clayton, K. M.; Bateman, Ian ...
International Journal of Environmental Studies,
11/1991, Volume:
39, Issue:
1-2
Book Review
Book reviews O'Riordan, Timothy; Clayton, K. M.; Bateman, Ian ...
International Journal of Environmental Studies,
11/1/1991, Volume:
39, Issue:
1-2
Book Review
Peer reviewed
MANAGING LEVIATHAN; ENVIRONMENTAL POLITICS AND THE ADMINISTRATIVE STATE, edited by Robert Paehike and Douglas Torgerson, Broadview Press, Peterborough, Ontario, 1990, 305 pp. (£10.95).
BETWEEN TWO ...WORLDS; SCIENCE, THE ENVIRONMENTAL MOVEMENT AND POLICY CHOICE, by Lynton K. Caldwell, Cambridge University Press, Cambridge, 1990, 219 pp., index (£32.00).
CHANGING DIRECTIONS, edited by Ken Dyer and John Young, Graduate Centre of Environmental Studies, University of Adelaide, Australia, 1990, 667 pp. (Austr. $40.00 (plus postage))
NATURAL RESOURCES: ALLOCATION ECONOMICS AND POLICY, by Judith Rees, Routledge, London and New York, 1990, second edition, 485 pp. (£60)
ENVIRONMENTAL ASSESSMENT: A PRACTICAL GUIDE, by C. A. Fortlage, Gower Technical, Aldershot, 1990, 152 pp. (£25.00)
EFFLUENT TREATMENT AND WASTE DISPOSAL, Institution of Chemical Engineers, Symposium Series No. 116, 1990, 402 pp., index ($114.00)
NITRATE POLLUTION AND POLITICS, by Jobst Conrad, Avebury Press, Aldershot, 1990, 88 pp., bibliography (£25.00)
WHEN THE BOUGH BREAKS: OUR CHILDREN, OUR ENVIRONMENT, by Lloyd Timberlake and Laura Thomas, Earthscan Publications, London, 1990, 250pp., paper bibliography, index (£6.95)
SHATTERING: FOOD POLITICS AND THE LOSS OF GENETIC DIVERSITY, by Cathy Fowler and Pat Mooney. The University of Arizona Press. Tucson, Arizona, 1990, 259 pp., index ($24.55 Hardback, $12.95 Paperback).
SUSTAINING EARTH. RESPONSE TO THE ENVIRONMENTAL THREATS, edited by D. J. R. Angell, J. D. Comer and M. L. N. Wilkinson, Macmillan, London, 1990, 226 pp., index (£7.99)
AN ECOSYSTEM APPROACH TO THE INTEGRITY OF THE GREAT LAKES IN TURBULENT TIMES, edited by Clayton J. Edwards and Henry A. Regier, Great Lakes Fisheries Commission, Ann Arbor, Mich., 1990, 285 pp. (£25.00)
TROPICAL RAINFOREST, by A. Newman, New York and Oxford: Facts on File, Oxford, 1990, 256 pp., index (£19.95)
YOU AND THE ENVIRONMENT, edited by Katie McBratney, Which? Books, Consumers' Association & Hodder & Stoughton, London, 1990,219 pp. (£8.95)
OUT OF PLACE: RESTORING IDENTITY TO THE REGIONAL LANDSCAPE, by M. Hough, Yale University Press, New Haven and London, 1990, index (£25.00)
A FRAGILE PARADISE. NATURE AND MAN IN THE PACIFIC, by A. Mitchell, Fontana/Collins, London, 1990, 256 pp., index (£9.99)
GLOBAL ENVIRONMENTAL ISSUES. A CLIMATOLOGICAL APPROACH, by D. D. Kemp, Routledge, London and New York: 1990, 220 pp., index (£9.99)
AFTER THE GREEN REVOLUTION, SUSTAINABLE DEVELOPMENT FOR AGRICULTURE, by G. R. Conway and E. B. Barbier, Earthscan Publications London, 1990, 205 pp., index (£8.95)
BARIUM AND ENVIRONMENTAL HEALTH CRITERIA 115, The International Programme on Chemical Safety (IPCS), Health Criteria 107 and 115, WHO, Geneva, 1990, 148 pp. ($13.60)
FULLY HALONGENATED CHLOROFLUOROCARBONS, The International Programme on Chemical Safety (IPCS) Health Criteria 113, WHO, Geneva, 1990, 164 pp. ($16.00)
1-PROPANOL AND 2-PROPANOL, The International Programme on Chemical Safety (IPCS), Health Criteria 102 and 103, WHO, Geneva, 1990, 98 pp. and 132 pp. ($11.20 and $12.80)
SURVIVING FIELDWORK, by N. Howell, A Report of the Advisory Panel on Health and Safety in Fieldwork. American Anthropological Association, Special Publication No. 26, Washington DC, 1990, 217 pp. ($12, members; $15, non-members)
OCCUPATIONAL EXPOSURE TO SILICA AND CANCER RISK, edited by C. Simonato, A. C. Fletcher, R. Saracci and T. L. Thomas, IARC Scientific Publications No. 97, Lyon. World Health Organization, International Agency for Research on Cancer, 1989, 124 pp. (£19.00)
TROPICAL RAINFOREST (World About Us Series), edited by F. Robertson, Gloucester Press, London, 1991, 32 pp., index (£5.99)
THE OZONE LAYER (World About Us Series), by M. Bright, Gloucester Press, London, 1991, 32 pp., index (£5.99)
THE GREENHOUSE EFFECT (World About Us Series), by M. Bright, Gloucester Press, London, 1991, 32 pp., index (£5.99)
ACID RAIN (World About Us Series), by M. Bright, Gloucester Press, London, 1991, 32 pp., index (£5.99)
GLOBAL WARMING, by A. Peckham, Franklin Watts, London, 1991,36 pp., index (£7.99)
CHANGING LANDSCAPES, by A. Peckham, Franklin Watts, London, 1991, 32 pp., index (£7.99)
FOOD AND FARMING, by S. Bechlake, Franklin Watts, London, 1991, 36 pp., glossary (£7.99)
THE GARDENING FROM WHICH? GUIDE TO GARDENING WITHOUT CHEMICALS, Hodder and Stoughton and the Consumers' Association, London, 1990, 144 pp. (£12.95)
PRACTICAL STATISTICS FOR FIELD BIOLOGY, by J. Fowler and L. Cohen, Open University Press, Milton Keynes, 1990 (No price given)
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