Background This study aimed to measure the preferences for mental health support among health professionals, their willingness to support the mental health of colleagues and associated factors. ...Method A descriptive cross-sectional study was performed from August to October 2022 within five hospitals located in Hanoi, Vietnam. A total of 244 health professionals participated in the study. Data on socio-economic status, health and COVID-19-related characteristics, Depression Anxiety Stress Scale (DASS-21); and preferences for mental health support services were collected by using a structured self-reported questionnaire. Multivariate logistic regression models were utilized to identify associated factors with the demand for mental support services. Results 13.9%, 17.1% and 8.6% reported having at least mild depression, anxiety and stress, respectively. There 13.9% did not seek any mental health support during the COVID-19 pandemic. The most common support included talking with friends (52.9%), family (50.8%), colleagues (47.6%) and using social networks/Internet (43.5%). There 31.1% had been aware of mental health services, but only 18.0% used this service at least once. Regarding preferences, 47.3% had a demand for mental support services, and the most preferred service was providing coping skills (25.9%), followed by skills to support others against mental problems (22.2%). Major sources of support included psychiatrists (34.4%), colleagues (29.1%) and family (27.9%). The main preferred channels for support included telephone/mobile phone (35.7%) and Internet (20.9%). Only 12.3% were willing to provide mental support for colleagues during the pandemic. Age, education, perceived mental health status, ever seeking any mental service, and DASS-21 depression score were associated with demand for mental support services. Conclusion This study found a lack of awareness of mental health services for health professionals, as well as moderate levels of demand for this service in this population. Raising awareness and developing tailored mental health support services are important to enhancing the mental well-being of health professionals in Vietnam to prepare for the next pandemic.
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DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Acute myeloid leukemia (AML) is the most aggressive hematopoietic malignancy characterized by uncontrolled proliferation of myeloid progenitor cells within the bone marrow. Tumor suppressor ...cylindromatosis (CYLD) is a deubiquitinating enzyme, which suppresses inflammatory response in macrophages. Macrophages have a central role in the defense against foreign substances and circulating cancer cells by their professional phagocytic capacity. Little is known about contributions of CYLD to changes in biological properties of human macrophages and its involvement in AML. The present study, therefore, explored whether macrophage functions in healthy individuals and AML patients are influenced by CYLD. To this end, ninety-two newly diagnosed AML patients and 80 healthy controls were recruited. The mRNA expression levels of inflammation-related genes were evaluated by real-time PCR, cell maturation, phagocytosis and apoptosis assays by flow cytometry and secretion of inflammatory cytokines by ELISA. As a result, AML patients with the low CYLD expression were significantly higher in M4/M5 than other subtypes according to the FAB type. The low CYLD expression was also closely associated with older patients and enhanced level of LDH in AML. Moreover, treatment of normal macrophages with CYLD siRNA enhanced activation of STAT-1, leading to increases in expressions of maturation markers and IL-6 production as well as suppression in cell apoptosis and phagocytosis, while macrophage phagocytosis from AML M4/M5b was higher than that from healthy controls upon CYLD siRNA transfection through STAT1 signalling. In conclusion, the inhibitory effects of CYLD on macrophage functions are expected to affect the immune response in AML.
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DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Permethrin, 3-Phenoxybenzyl (1 RS)-cis,trans-3-(2,2-dichlorovinyl)- 2,2-dimethylcyclopropanecarboxylate, has a wide range of applications like insecticide, insect repellent and prevents ...mosquito-borne diseases, such as dengue fever and malaria in tropical areas. In this work, we develop a prominent monitoring method for the detection of permethrin pesticide using surface-enhanced Raman scattering (SERS) optical fibre substrates. The novel SERS-active optical fibre substrates were grown and deposited silver (Ag) nano-dendrites on the end of multi-mode fibre core by laser-assisted photochemical method. The characteristic of the Ag-nanostructures could be controlled by the experimental conditions, namely, laser illumination time. Ag nanoparticles optical fibre substrates and Ag nano-dendrites optical fibre substrates were prepared with laser illumination time of 3 min and 8 min, respectively. The achieved SERS-activity optical fibre substrates were tested with Rhodamine 6G aqueous solutions. We demonstrate that the SERS activity coupled with Ag nano-dendrites optical fibre substrate has higher Raman enhancement factor due to the creation of many of hot-spots for amplifying Raman signals. Besides, the stability and reproducibility of the Ag nano-dendrites optical fibre substrate were also evaluated with stored time of 1000 hours and relative standard deviation of less than 3%. The Ag nano-dendrite optical fibre substrate was selected for detection of permethrin pesticide in the concentration range of 0.1 ppm-20 ppm with limit of quantification (LOQ) of 0.1 ppm and calculated limit of detection (LOD) of 0.0035 ppm, proving its great potential for direct, rapid detection and monitoring of permethrin.
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IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
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•DWCNTs-Gr hybrid thin film was successfully synthesized by LPCVD method.•A novel structure of DWCNTs-Gr hybrid thin film modified SPE was prepared.•An electrochemical sensor using ...ChOx enzyme for detection of As(V) was developed.•A high sensitive sensor was achieved with low LOD for As(V) detection.
In this work, we demonstrate the preparation of hybrid thin films based on double-walled carbon nanotubes and graphene for electrochemical sensing applications. The hybrid films were synthesized on polycrystalline copper foil by thermal chemical vapor deposition under low pressure. This carbonaceous hybrid film has exhibited high transparency with a transmittance of 94.3 %. The occurrence of this hybrid material on the electrode surface of screen-printed electrodes was found to increase electroactive surface area by 1.4 times, whereas electrochemical current was enhanced by 2.4 times. Such a highly transparent and conductive hybrid film was utilized as a transducing platform of enzymatic electrochemical arsenic(V) sensor. The as-prepared sensor shows the linear detection of arsenic(V) in the range from 1 to 10 ppb, with a limit of detection as low as 0.287 ppb. These findings provide a promising approach to develop new multifunctional electrochemical sensing systems for environmental monitoring and biomedical diagnostics.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
Methylene blue (MB) is a toxic organic substance which has been widely used in industry and pharmacy, and it poses a threat to the environment and security due to its toxic properties. Here, a device ...consisting of porous silicon photonic crystals covered with silver nanoparticles has been introduced for the select and rapid detection of MB by the emerging specific Raman peak at ~ 446 cm
−1
.
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EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
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•The binding and orientation of TBZ molecular skeleton on the surface of Au NP.•The binding and orientation of TBZ molecular skeleton on the surface of AuAg BNP.•532 nm SERS of TBZ ...for Au NPs, AuAg BNPs and Ag NPs were performed for comparison.
Au-Ag bimetallic nanoparticles (BNPs) with varying molar fractions as Au0.2Ag0.8 and Au0.3Ag0.7 are prepared on porous silicon. They were demonstrated as surface-enhanced Raman scattering (SERS) substrate for the detection of thiabendazole (TBZ) molecules. The concentration of TBZ investigated is 10-7 M. The effect of the Au content on SERS properties of the Au-Ag BNPs was studied. Furthermore, the composition dependent SERS spectra and adsorption mechanism of TBZ on Au-Ag BNPs surfaces were discussed.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
In this paper, a parallel group detection (PGD) algorithm is proposed in order to address the degradation in the bit error rate (BER) performance of linear detectors when they are used in high-load ...massive MIMO systems. The algorithm is constructed by converting the equivalent extended massive MIMO system into two subsystems, which can be simultaneously detected by the classical detection procedures. Then, using the PGD and the classical ZF as well as the QR-decomposition- (QRD-) based detectors, we proposed two new detectors, called ZF-based PGD (ZF-PGD) and QRD-based PGD (QRD-PGD). The PGD is further combined with the sorted longest basis (SLB) algorithm to make the signal recovery more accurate, thereby resulting in two new detectors, namely, the ZF-PGD-SLB and the QRD-PGD-SLB. Various complexity evaluations and simulations prove that the proposed detectors can significantly improve the BER performance compared to their classical linear and QRD counterparts with the practical complexity levels. Hence, our proposed detectors can be used as efficient means of estimating the transmitted signals in high-load massive MIMO systems.
Contamination levels and distribution patterns of ten typical phthalic acid esters (PAEs) were investigated in various types of water samples collected from Hanoi metropolitan area in Vietnam. ...Concentrations of 10 PAEs in bottled water, tap water, lake water, and wastewater samples were measured in the ranges of 1640–15,700 ng/L (mean/median: 6400/5820 ng/L), 2100–18,000 ng/L (mean/median: 11,200/9270 ng/L), 19,600–127,000 ng/L (mean/median: 51,800/49,300 ng/L), and 20,700–405,000 ng/L (mean/median: 121,000/115,000 ng/L), respectively. Among PAEs, di-(2-ethylhexyl) phthalate (DEHP) accounted for a major proportion of total concentrations (45%) in wastewater, followed by diisobutyl phthalate (DiBP, 10.3%), and dibutyl phthalate (DBP, 9.53%). Concentrations of PAEs in wastewater decreased significantly with distance from the wastewater treatment plants (WWTPs). Concentrations of PAEs in surface water samples did not vary greatly between locations. PAEs were found in bottled water in the following order: DBP (22.4%), DiBP (22.3%), benzylbutyl phthalate (BzBP, 20.1%), and DEHP (15.5%). The estimated mean exposure doses of 10 PAEs through consumption of drinking water for adults and children in Vietnam were 254 and 256 ng/kg-bw/day, respectively.
Capsule: Highest concentrations of PAEs were measured in wastewater, followed by lake water, tap water, and bottled water.
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•Elevated concentrations of PAEs were measured in wastewater samples from Vietnam.•DEHP was a major compound found in tap water, lake water and wastewater samples.•DiBP and DBP were the dominant PAEs in bottled water.•PAE concentrations in drinking water and associated exposure doses were below the reference values.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
The residue concentrations and congener profiles of polychlorinated dibenzo-
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-dioxins/furans (PCDD/Fs) were examined in fly ash and bottom ash released from different thermal industrial processes ...in Vietnam. PCDD/F concentrations and toxic equivalents (TEQs) in the ash samples varied greatly and decreased in the following order: steel making > aluminum recycling > medical waste incinerator > boilers > municipal waste incinerator > tin production > brick production > coal-fired power plant. Both the precursor and de novo synthesis were estimated as possible formation mechanisms of dioxins in the ash, but the latter pathway was more prevalent. The highest emission factors were estimated for the ash released from some steel-making plants, aluminum-recycling facilities, and a medical waste incinerator. The emission factors of PCDD/Fs in ash released from some steel plants of this study were two to six times higher than the UNEP Toolkit default value. The annual emission amount of ash-bound dioxins produced by 15 facilities in our study was estimated to be 26.2 to 28.4 g TEQ year
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, which mainly contributed by 3 steel plants. Health risk related to the dioxin-containing ash was evaluated for workers at the studied facilities, indicating acceptable risk levels for almost all individuals. More comprehensive studies on the occurrence and impacts of dioxins in waste streams from incineration and industrial processes and receiving environments should be conducted, in order to promote effective waste management and health protection scheme for dioxins and related compounds in this rapidly industrializing country.
In this paper, a very low complexity Lattice Reduction technique, called Dual Shortest Longest Vector algorithm (SLV), is adopted to improve the Bit Error Rate (BER) performance of the Minimum Mean ...Square Error (MMSE) detector in high-load Massive MIMO systems, whereby resulting in the so-called SLV-aided MMSE (MMSE–SLV) detector. An efficient combination scheme of Generalized Group Detection (GGD) algorithm and the MMSE–SLV, called MMSE–GGD–SLV, is further proposed to enhance BER performance of the system more significantly. In order to do so, we first convert the Group Detection approach to the generalized one (GGD) by creating an arbitrary number of sub-systems. Then, an additional operation, i.e., channel matrix sorting, is applied to the GGD to reduce the error propagation between sub-systems. To make the detection complexities of the MMSE–GGD–SLV detector more practical, the MMSE–SLV detection procedure is only applied to the first sub-system. Various BER performance simulations and complexity analysis show that both the MMSE–GGD–SLV and the MMSE–SLV detectors noticeably outperform their conventional MMSE counterpart, yet at the cost of higher detection complexities. However, their complexities are kept at acceptable levels, which are much lower than those of the conventional BLAST detector. Therefore, the proposed detectors are very good candidates for signal recovery in high load Massive MIMO systems.
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EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OBVAL, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
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