We construct a toric generalised K\"ahler structure on $\mathbb{C}P^2$ and
show that the various structures such as the complex structure, metric etc are
expressed in terms of certain elliptic ...functions. We also compute the
generalised K\"ahler potential in terms of integrals of elliptic functions.
Pheochromocytoma is a rare tumor that secretes excess catecholamines. Pheochromocytoma crises may be precipitated by the use of several drugs. This article describes the case of a patient affected by ...pheochromocytoma in whom multiple organ failure developed after contemporary administration of ergotamine, caffeine, and nimesulide. The patient recovered completely long after surgical intervention.
The purpose of this paper is to investigate shifted \((+1)\) Poisson structures in context of differential geometry. The relevant notion is shifted \((+1)\) Poisson structures on differentiable ...stacks. More precisely, we develop the notion of Morita equivalence of quasi-Poisson groupoids. Thus isomorphism classes of \((+1)\) Poisson stack correspond to Morita equivalence classes of quasi-Poisson groupoids. In the process, we carry out the following programs of independent interests: (1) We introduce a \(\mathbb Z\)-graded Lie 2-algebra of polyvector fields on a given Lie groupoid and prove that its homotopy equivalence class is invariant under Morita equivalence of Lie groupoids, thus can be considered as polyvector fields on the corresponding differentiable stack \({\mathfrak X}\). It turns out that shifted \((+1)\) Poisson structures on \({\mathfrak X}\) correspond exactly to elements of the Maurer-Cartan moduli set of the corresponding dgla. (2) We introduce the notion of tangent complex \(T_{\mathfrak X}\) and cotangent complex \(L_{\mathfrak X}\) of a differentiable stack \({\mathfrak X}\) in terms of any Lie groupoid \(\Gamma{\rightrightarrows} M\) representing \({\mathfrak X}\). They correspond to homotopy class of 2-term homotopy \(\Gamma\)-modules \(A1\rightarrow TM\) and \(T^\vee M\rightarrow A^\vee-1\), respectively. We prove that a \((+1)\)-shifted Poisson structure on a differentiable stack \({\mathfrak X}\), defines a morphism \({L_{{\mathfrak X}}}1\to {T_{{\mathfrak X}}}\).
We study an equivariant extension of the Batalin-Vilkovisky formalism for quantizing gauge theories. Namely, we introduce a general framework to encompass failures of the quantum master equation, and ...we apply it to the natural equivariant extension of AKSZ solutions of the classical master equation (CME). As examples of the construction, we recover the equivariant extension of supersymmetric Yang-Mills in 2d and of Donaldson-Witten theory.
Background Head-up tilt testing is extensively used to determine the vasovagal origin of syncope in patients with otherwise unexplained loss of consciousness, although issues remain regarding the ...method of the test. The diagnostic value of a shortened head-up tilt test potentiated with sublingual nitroglycerin was assessed in patients with unexplained syncope.
Methods Two hundred two patients (mean age 49 ± 19 years) with syncope of unknown origin and 34 subjects in a control group (mean age 45 ± 17 years) were studied. The patients and the subjects in the control group were tilted upright to 60 degrees for 20 minutes. If syncope did not occur, sublingual nitroglycerin (400 μg) was administered, and observation was continued for 25 more minutes.
Results During the unmedicated phase syncope occurred in 22 (11%) patients and in one member of the control group. After nitroglycerin was administered, syncope occurred in 119 (59%) patients and in 1 (3%) member of the control group. False-positive response (exaggerated response) was observed in eight (4%) patients and in four (12%) subjects in the control group. The total positivity rate of the test was 70% with a specificity rate of 94%.
Conclusions Short-duration head-up tilt test potentiated with sublingual nitroglycerin provides an adequate specificity and positivity rate in patients with unexplained syncope. (Am Heart J 1998;135:564-70.)
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IJS, IMTLJ, KILJ, KISLJ, NUK, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
Shortened head-up tilt testing (HUT) potentiated with sublingual nitroglycerin (60° passive standing for 20 minutes followed, if negative, by 400 μg of sublingual nitroglycerin spray with the test ...continuing for another 20 minutes) differs from conventional nitroglycerin HUT for a shorter drug-free phase (20 vs 45 minutes). To compare the positivity rate of the 2 protocols, both tests were performed in a randomized sequence in 10 patients with unexplained syncope (study 1), and another 42 patients were randomly assigned either to conventional or to shortened nitroglycerin HUT (study 2). To evaluate the reproducibility of the shortened nitroglycerin HUT, another 38 patients with unexplained syncope underwent 2 consecutive tests within a 7 ± 8 day interval (study 3). Finally, to evaluate the specificity of the test, 47 control subjects underwent shortened nitroglycerin HUT (study 4). Seven positive responses were observed during shortened nitroglycerin HUT, and there were 8 positive responses during conventional nitroglycerin HUT (p = NS) in the study 1 group. Fifteen positive (71%) responses, 5 negative responses, and 1 exaggerated response were observed during shortened nitroglycerin HUT; 16 positive (76%, p = NS vs shortened nitroglycerin HUT), 3 negative, and 2 exaggerated responses were observed during conventional nitroglycerin HUT in the study 2 group. During the first test, 21 patients (55%) had a positive, 15 patients had a negative, and 2 patients had an exaggerated response in study group 3. During the second test, 15 positive (39%), 19 negative, and 4 exaggerated responses were observed. Thus, the reproducibility was 67% for a positive and 94% for a negative test. In control subjects, 2 positive (4%) responses, 38 negative, and 7 exaggerated responses were observed with a specificity of 96% in study group 4. In patients with unexplained syncope, shortened nitroglycerin HUT allowed a positivity rate similar to that of the conventional test. Moreover, the shortened test provided a high specificity and adequate reproducibility for both the positive and the negative responses.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
The advantage of delivering chemotherapy by hepatic arterial infusion is the acquisition of a high concentration of the drug in the target. Irinotecan (CPT-11) is active for the treatment of advanced ...colorectal cancer. In phase I studies, doses of 20 mg/m2/d for 5 days given every 4 weeks as continuous infusion or 200 mg/m2 as a short 30-min infusion given every 3 weeks is recommended for phase II studies.
Twelve patients with a median liver substitution of 30% (20-50%) were enrolled, 6 progressed after a FOLFOX-induced partial response and 6 progressed after 5-fluorouracil and folinic acid. All patients had a surgically (n = 6) or angiographically placed port (n = 6). They received hepatic arterial infusion chemotherapy with CPT-11 (200 mg/m2) on an out-patient basis, every 3 weeks as a short 30-min infusion for six cycles.
Four partial responses were observed (33%) lasting 24, 15, 12 and 8+ weeks, 3 stable disease (25%) lasting more than 12 weeks, and 5 progressions (41%). Six patients (50%) presented a >30% reduction in CEA. Toxicity was G2 diarrhea in 5 patients (41%) and G2 myelosuppression in 6 (50%); one patient had abdominal right upper quadrant pain requiring analgesics.
CPT-11 is active as hepatic arterial infusion chemotherapy in liver metastases from colorectal cancer and can rescue systemically pretreated patients. Our schedule seems safe, feasible and well accepted on an out-patient basis.
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NUK, OILJ, SAZU, UKNU, UL, UM, UPUK
To compare reperfusion times and in-hospital outcome of patients with STEMI treated with primary percutaneous coronary intervention (PCI) in a teaching hospital (TH) with or without inter-hospital ...transfer and in community hospitals.
We performed a retrospective analysis of 536 patients with STEMI treated between January 2005 and December 2006 with primary PCI. Three groups were identified. A: 207 patients presented to the TH. B: 121 patients transferred to TH from metropolitan area hospitals (MAH). C: 208 patients presented in two rural area hospitals (RAH) with primary PCI capability. Baseline characteristics were similar. Door-to-balloon (DtB) times were significantly (p<0.001) higher in group B (median 120, range 90-180 min) both compared to group A (median 60, range 45-90 min) and C (median 73, range 55-99 min). In group B 79,5% of patients present a DtB > 90 min. In-hospital mortality was 4.9%, 3.3% and 4.3% respectively in group A, B and C without significant differences.
The expansion of primary PCI to RAH achieves reperfusion delays similar to that of patients admitted to TH. Transferred patients present very higher DtB when compared to patients treated on-site. In-hospital outcome are similar but further studies are warranted.
We discuss the A-model as a gauge fixing of the Poisson Sigma Model with target a symplectic structure. We complete the discussion in arXiv:0706.3164, where a gauge fixing defined by a compatible ...complex structure was introduced, by showing how to recover the A-model hierarchy of observables in terms of the AKSZ observables. Moreover, we discuss the off-shell supersymmetry of the A-model as a residual BV symmetry of the gauge-fixed PSM action.
