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  • The SGLT-2 inhibitor empagl... The SGLT-2 inhibitor empagliflozin improves myocardial strain, reduces cardiac fibrosis and pro-inflammatory cytokines in non-diabetic mice treated with doxorubicin
    Quagliariello, Vincenzo; De Laurentiis, Michelino; Rea, Domenica ... Cardiovascular diabetology, 07/2021, Volume: 20, Issue: 1
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    Empagliflozin (EMPA), a selective inhibitor of the sodium glucose co-transporter 2, reduced the risk of hospitalization for heart failure and cardiovascular death in type 2 diabetic patients in the ...
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  • Virtual reality and music t... Virtual reality and music therapy as distraction interventions to alleviate anxiety and improve mood states in breast cancer patients during chemotherapy
    Chirico, Andrea; Maiorano, Patrizia; Indovina, Paola ... Journal of cellular physiology, June 2020, Volume: 235, Issue: 6
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    Psychological distress is a common consequence of breast cancer diagnosis and treatment and could further exacerbate therapy side effects. Interventions increasing treatment tolerance are crucial to ...
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  • International validation of... International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study
    Pagès, Franck; Mlecnik, Bernhard; Marliot, Florence ... The Lancet (British edition), 05/2018, Volume: 391, Issue: 10135
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    The estimation of risk of recurrence for patients with colon carcinoma must be improved. A robust immune score quantification is needed to introduce immune parameters into cancer classification. The ...
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  • LncRNA HOTAIR in Tumor Micr... LncRNA HOTAIR in Tumor Microenvironment: What Role?
    Botti, Gerardo; Scognamiglio, Giosuè; Aquino, Gabriella ... International journal of molecular sciences, 05/2019, Volume: 20, Issue: 9
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    lncRNAs participate in many cellular processes, including regulation of gene expression at the transcriptional and post-transcriptional levels. In addition, many lncRNAs can contribute to the ...
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  • Long Non-Coding RNA HOTAIR ... Long Non-Coding RNA HOTAIR in Breast Cancer Therapy
    Cantile, Monica; Di Bonito, Maurizio; Cerrone, Margherita ... Cancers, 05/2020, Volume: 12, Issue: 5
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    Breast cancer (BC) is the most common cancer type among women, and morbidity and mortality rates are still very high. Despite new innovative therapeutic approaches for all BC molecular subtypes, the ...
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  • Functional Interaction amon... Functional Interaction among lncRNA HOTAIR and MicroRNAs in Cancer and Other Human Diseases
    Cantile, Monica; Di Bonito, Maurizio; Tracey De Bellis, Maura ... Cancers, 02/2021, Volume: 13, Issue: 3
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    LncRNAs are a class of non-coding RNAs mostly involved in regulation of cancer initiation, metastatic progression, and drug resistance, through participation in post-transcription regulatory ...
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  • LncRNA HOTAIR as Prognostic Circulating Marker and Potential Therapeutic Target in Patients with Tumor Diseases
    Botti, Gerardo; Marra, Laura; Malzone, Maria Gabriella ... Current drug targets, 01/2017, Volume: 18, Issue: 1
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    In the recent years the importance of the role played by non-coding RNA on the regulation of gene expression was increased by numerous studies. The research mainly focused on small ncRNAs, such as ...
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  • Multicenter International S... Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer
    Mlecnik, Bernhard; Bifulco, Carlo; Bindea, Gabriela ... Journal of clinical oncology, 11/2020, Volume: 38, Issue: 31
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    The purpose of this study was to evaluate the prognostic value of Immunoscore in patients with stage III colon cancer (CC) and to analyze its association with the effect of chemotherapy on time to ...
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  • Can Beta-2-Adrenergic Pathw... Can Beta-2-Adrenergic Pathway Be a New Target to Combat SARS-CoV-2 Hyperinflammatory Syndrome?-Lessons Learned From Cancer
    Barbieri, Antonio; Robinson, Nirmal; Palma, Giuseppe ... Frontiers in immunology, 09/2020, Volume: 11
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    SARS-CoV-2 infection is a new threat to global public health in the 21 century (2020), which has now rapidly spread around the globe causing severe pneumonia often linked to Acute Respiratory ...
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  • BRAF/NRAS Mutation Frequenc... BRAF/NRAS Mutation Frequencies Among Primary Tumors and Metastases in Patients With Melanoma
    COLOMBINO, Maria; CAPONE, Mariaelena; PAGANI, Elena ... Journal of clinical oncology, 07/2012, Volume: 30, Issue: 20
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    The prevalence of BRAF, NRAS, and p16CDKN2A mutations during melanoma progression remains inconclusive. We investigated the prevalence and distribution of mutations in these genes in different ...
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