The aim of the SYRMA-CT collaboration is to set-up the first clinical trial of phase-contrast breast CT with synchrotron radiation (SR). In order to combine high image quality and low delivered dose ...a number of innovative elements are merged: a CdTe single photon counting detector, state-of-the-art CT reconstruction and phase retrieval algorithms. To facilitate an accurate exam optimization, a Monte Carlo model was developed for dose calculation using GEANT4. In this study, high isotropic spatial resolution (120 μm)3 CT scans of objects with dimensions and attenuation similar to a human breast were acquired, delivering mean glandular doses in the range of those delivered in clinical breast CT (5-25 mGy). Due to the spatial coherence of the SR beam and the long distance between sample and detector, the images contain, not only absorption, but also phase information from the samples. The application of a phase-retrieval procedure increases the contrast-to-noise ratio of the tomographic images, while the contrast remains almost constant. After applying the simultaneous algebraic reconstruction technique to low-dose phase-retrieved data sets (about 5 mGy) with a reduced number of projections, the spatial resolution was found to be equal to filtered back projection utilizing a four fold higher dose, while the contrast-to-noise ratio was reduced by 30%. These first results indicate the feasibility of clinical breast CT with SR.
An innovative X-ray imaging sensor based on Chromatic Photon Counting technology with intrinsic digital characteristics is presented. The system counts individually the incident X-ray photons and ...selects them according to their energy to produce two color images per exposure. The energy selection occurs in real time and at radiographic imaging speed (GHz global counting rate). Photon counting, color mode and a very fine spatial resolution (more than 10LP/mm at MTF50) allow to obtain a high ratio between image quality and absorbed dose. The individual building block of the imaging system is a two-side buttable semiconductor radiation detector made of a thin pixellated CdTe crystal coupled to a large area VLSI CMOS pixel ASIC. Modules with 1, 2, 4, and 8 block units have been built. The largest module has 25 x 2:5 cm super(2) sensitive area. Results and images obtained from testing different modules are presented.
PIXIE III is the third generation of very large area (32 x 25 mm super(2)) pixel ASICs developed by Pixirad Imaging Counters s.r.l. to be used in combination with suitable X-ray sensor materials ...(Silicon, CdTe, GaAs) in hybrid assemblies using flip-chip bonding. A Pixirad unit module based on PIXIE III shows several advances compared to what has been available up to now. It has a very broad energy range (from 2 to 100 keV before full pulse saturation), high speed (100 ns peaking time), high frame rate (larger than 500 fps), dead-time-free operation, good energy resolution (around 2 keV at 20 keV), high photo-peak fraction and sharp spectral separation between the color images. In this paper the results obtained with PIXIE III both in a test bench set-up as well in X-ray imaging applications are discussed.
Assembly and test of the gas pixel detector for X-ray polarimetry Li, H.; Feng, H.; Muleri, F. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
12/2015, Volume:
804
Journal Article
Peer reviewed
Open access
The gas pixel detector (GPD) dedicated for photoelectric X-ray polarimetry is selected as the focal plane detector for the ESA medium-class mission concept X-ray Imaging and Polarimetry Explorer ...(XIPE). Here we show the design, assembly, and preliminary test results of a small GPD for the purpose of gas mixture optimization needed for the phase A study of XIPE. The detector is assembled in house at Tsinghua University following a design by the INFN-Pisa group. The improved detector design results in a good uniformity for the electric field. Filled with pure dimethyl ether (DME) at 0.8atm, the measured energy resolution is 18% at 6keV and inversely scales with the square root of the X-ray energy. The measured modulation factor is well consistent with that from simulation, up to ~0.6 above 6keV. The residual modulation is found to be 0.30±0.15% at 6keV for the whole sensitive area, which can be translated into a systematic error of less than 1% for polarization measurement at a confidence level of 99%. The position resolution of the detector is about 80μm in FWHM, consistent with previous studies and sufficient for XIPE requirements.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
The aim of this work is the characterization of the Pixirad-1 detector system with monochromatic synchrotron radiation at different energies. The linearity of the system has been investigated varying ...the impinging photon flux up to paralyzation. The ratio between detector counts and number of impinging photons, as a function of energy and discriminator thresholds, has been measured. The pixel noise has been evaluated and the result compared with the theoretical Poisson model. Eventually, the spatial resolution has been evaluated by measuring the line-spread function at different energies and discriminator thresholds.
X-rays are particularly suited to probing the physics of extreme objects. However, despite the enormous improvements of X-ray astronomy in imaging, spectroscopy, and timing, polarimetry remains ...largely unexplored. We propose the photoelectric polarimeter Gas Pixel Detector (GPD) as a candidate instrument to fill the gap created by more than 30 yr without measurements. The GPD, in the focus of a telescope, will increase the sensitivity of orders of magnitude. Moreover, since it can measure the energy, the position, the arrival time, and the polarization angle of every single photon, it allows us to perform polarimetry of subsets of data singled out from the spectrum, the light curve, or an image of the source. The GPD has an intrinsic, very fine imaging capability, and in this work we report on the calibration campaign carried out in 2012 at the PANTER X-ray testing facility of the Max-Planck-Institut fur extraterrestrische Physik of Garching (Germany) in which, for the first time, we coupled it with a JET-X optics module with a focal length of 3.5 m and an angular resolution of 18 arc sec at 4.5 keV. This configuration was proposed in 2012 aboard the X-ray Imaging Polarimetry Explorer (XIPE) in response to the ESA call for a small mission. We derived the imaging and polarimetric performance for extended sources like pulsar wind nebulae and supernova remnants as case studies for the XIPE configuration and also discuss possible improvements by coupling the detector with advanced optics that have a finer angular resolution and larger effective areas to study extended objects with more detail.
The SYRMA-CT project aims to set-up the first clinical trial of phase-contrast breast Computed Tomography with synchrotron radiation at the SYRMEP beamline of Elettra, the Italian synchrotron light ...source. The challenge in a dedicated breast CT is to match a high spatial resolution with a low dose level. In order to fulfil these requirements, the SYRMA-CT project uses a large area CdTe single photon counting detector (Pixirad-8), simultaneous algebraic reconstruction technique (SART) and phase retrieval pre-processing. This work investigates the imaging performances of the system in a continuous acquisition mode and with a low dose level towards the clinical application. A custom test object and a large surgical sample have been studied.
The Gas Pixel Detector belongs to the very limited class of gas detectors optimized for the measurement of X-ray polarization in the emission of astrophysical sources. The choice of the mixture in ...which X-ray photons are absorbed and photoelectrons propagate, deeply affects both the energy range of the instrument and its performance in terms of gain, track dimension and ultimately, polarimetric sensitivity. Here we present the characterization of the Gas Pixel Detector with a 1
cm thick cell filled with dimethyl ether (DME) at 0.79
atm, selected among other mixtures for the very low diffusion coefficient. Almost completely polarized and monochromatic photons were produced at the calibration facility built at INAF/IASF-Rome exploiting Bragg diffraction at nearly 45°. For the first time ever, we measured the modulation factor and the spectral capabilities of the instrument at energies as low as 2.0
keV, but also at 2.6, 3.7, 4.0, 5.2 and 7.8
keV. These measurements cover almost completely the energy range of the instrument and allows to compare the sensitivity achieved with that of the standard mixture, composed of helium and DME.
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X-ray diffraction (XRD) is a powerful tool for material identification. In order to interpret XRD data, knowledge is required of the scattering angles and energies of X-rays which interact with the ...sample. By using a pixellated, energy-resolving detector, this knowledge can be gained when using a spectrum of unfiltered X-rays, and without the need to collimate the scattered radiation. Here we present results of XRD measurements taken with the Pixirad detector and a laboratory-based X-ray source. The cadmium telluride sensor allows energy windows to be selected, and the 62 mum pixel pitch enables accurate spatial information to be preserved for XRD measurements, in addition to the ability to take high resolution radiographic images. Diffraction data are presented for a variety of samples to demonstrate the capability of the technique for materials discrimination in laboratory, security and pharmaceutical environments. Distinct diffraction patterns were obtained, from which details on the molecular structures of the items under study were determined.
The Tracker subsystem of the Large Area Telescope (LAT) science instrument of the Gamma-ray Large Area Space Telescope (GLAST) mission has been completed and tested. It is the central detector ...subsystem of the LAT and serves both to convert an incident gamma-ray into an electron–positron pair and to track the pair in order to measure the gamma-ray direction. It also provides the principal trigger for the LAT. The Tracker uses silicon strip detectors, read out by custom electronics, to detect charged particles. The detectors and electronics are packaged, along with tungsten converter foils, in 16 modular, high-precision carbon-composite structures. It is the largest silicon-strip detector system ever built for launch into space, and its aggressive design emphasizes very low power consumption, passive cooling, low noise, high efficiency, minimal dead area, and a structure that is highly transparent to charged particles. The test program has demonstrated that the system meets or surpasses all of its performance specifications as well as environmental requirements. It is now installed in the completed LAT, which is being prepared for launch in early 2008.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
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