Issues surrounding wound healing have garnered deep scientific interest as well as booming financial markets invested in novel wound therapies. Much progress has been made in the field, but it is ...unsurprising to find that recent successes reveal new challenges to be addressed. With regard to wound healing, large tissue deficits, recalcitrant wounds, and pathological scar formation remain but a few of our most pressing challenges. Stem cell-based therapies have been heralded as a promising means by which to surpass current limitations in wound management. The wide differentiation potential of stem cells allows for the possibility of restoring lost or damaged tissue, while their ability to immunomodulate the wound bed from afar suggests that their clinical applications need not be restricted to direct tissue formation. The clinical utility of stem cells has been demonstrated across dozens of clinical trials in chronic wound therapy, but there is hope that other aspects of wound care will inherit similar benefit. Scientific inquiry into stem cell-based wound therapy abounds in research labs around the world. While their clinical applications remain in their infancy, the heavy investment in their potential makes it a worthwhile subject to review for plastic surgeons, in terms of both their current and future applications.
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FZAB, GIS, IJS, IZUM, KILJ, NLZOH, NUK, OILJ, PILJ, PNG, SAZU, SBCE, SBMB, UL, UM, UPUK
Footstep Planning for the Honda ASIMO Humanoid Chestnutt, J.; Lau, M.; Cheung, G. ...
Proceedings of the 2005 IEEE International Conference on Robotics and Automation,
2005
Conference Proceeding
Despite the recent achievements in stable dynamic walking for many humanoid robots, relatively little navigation autonomy has been achieved. In particular, the ability to autonomously select foot ...placement positions to avoid obstacles while walking is an important step towards improved navigation autonomy for humanoids. We present a footstep planner for the Honda ASIMO humanoid robot that plans a sequence of footstep positions to navigate toward a goal location while avoiding obstacles. The possible future foot placement positions are dependent on the current state of the robot. Using a finite set of state-dependent actions, we use an A* search to compute optimal sequences of footstep locations up to a time-limited planning horizon. We present experimental results demonstrating the robot navigating through both static and dynamic known environments that include obstacles moving on predictable trajectories.
We study the emergence of magnetic flux from the near-surface layers of the
solar convection zone into the photosphere. To model magnetic flux emergence,
we carried out a set of numerical radiative ...magnetohydrodynamics simulations.
Our simulations take into account the effects of compressibility, energy
exchange via radiative transfer, and partial ionization in the equation of
state. All these physical ingredients are essential for a proper treatment of
the problem. Furthermore, the inclusion of radiative transfer allows us to
directly compare the simulation results with actual observations of emerging
flux. We find that the interaction between the magnetic flux tube and the
external flow field has an important influence on the emergent morphology of
the magnetic field. Depending on the initial properties of the flux tube (e.g.
field strength, twist, entropy etc.), the emergence process can also modify the
local granulation pattern. The emergence of magnetic flux tubes with a flux of
$10^{19}$ Mx disturbs the granulation and leads to the transient appearance of
a dark lane, which is coincident with upflowing material. These results are
consistent with observed properties of emerging magnetic flux.
Quota samples were drawn from those who are in the waiting list of the Care and Attention Homes and Infirmary, and those who are living in the government subvented Care and Attention homes (C&A ...homes, designed for those who require some nursing and personal care) and infirmaries (for the frail ones), and unregistered private nursing homes. Respondents aged 70 to 80 were selected, as most on the waiting lists and currently in institutions are within this age range. A total of 202 elderly were interviewed, and 162 were included in the final analysis. Findings indicated that those living in the Care and Attention Homes run by the Government, which presumably meet the sample needs adequately, have the lowest depression level and highest level of satisfaction with care when compared to their counterparts in other type of institutions. On the other hand, those receiving services in those unregistered private homes and infirmary, in which services were offered at a level lower than their needs, have the highest level of depression among samples studied. The study was carried out between March 1991 to December 1992.
We study the emergence of magnetic flux from the near-surface layers of the solar convection zone into the photosphere. To model magnetic flux emergence, we carried out a set of numerical radiative ...magnetohydrodynamics simulations. Our simulations take into account the effects of compressibility, energy exchange via radiative transfer, and partial ionization in the equation of state. All these physical ingredients are essential for a proper treatment of the problem. Furthermore, the inclusion of radiative transfer allows us to directly compare the simulation results with actual observations of emerging flux. We find that the interaction between the magnetic flux tube and the external flow field has an important influence on the emergent morphology of the magnetic field. Depending on the initial properties of the flux tube (e.g. field strength, twist, entropy etc.), the emergence process can also modify the local granulation pattern. The emergence of magnetic flux tubes with a flux of \(10^{19}\) Mx disturbs the granulation and leads to the transient appearance of a dark lane, which is coincident with upflowing material. These results are consistent with observed properties of emerging magnetic flux.