The usefulness of flavin-based aerial photooxidation in esterification under Mitsunobu reaction conditions was demonstrated, providing aerial dialkyl azodicarboxylate recycling/generation from the ...corresponding dialkyl hydrazine dicarboxylate. Simultaneously, activation of triphenylphosphine (Ph
P) by photoinduced electron transfer from flavin allows azo-reagent-free esterification. An optimized system with 3-methylriboflavin tetraacetate (10%), oxygen (terminal oxidant), visible light (450 nm), Ph
P, and dialkyl hydrazine dicarboxylate (10%) has been shown to provide efficient and stereoselective coupling of various alcohols and acids to esters with retention of configuration.
Pierre Auger Observatory operates the largest system of detectors for ultra-high energy cosmic ray measurements. Comparison of theoretical models of interactions with recorded data requires thousands ...of computing cores for Monte Carlo simulations. Since 2007 distributed resources connected via EGI grid are successfully used. The first and the second versions of production system based on bash scripts and MySQL database were able to submit jobs to all reliable sites supporting Virtual Organization auger. For many years VO auger belongs to top ten of EGI users based on the total used computing time. Migration of the production system to DIRAC interware started in 2014. Pilot jobs improve efficiency of computing jobs and eliminate problems with small and less reliable sites used for the bulk production. The new system has also possibility to use available resources in clouds. Dirac File Catalog replaced LFC for new files, which are organized in datasets defined via metadata. CVMFS is used for software distribution since 2014. In the presentation we give a comparison of the old and the new production system and report the experience on migrating to the new system.
E-learning is a modern and effective approach for training in various areas and at different levels of education. This paper gives an overview of SyRoTek, an e-learning platform for mobile robotics, ...artificial intelligence, control engineering, and related domains. SyRoTek provides remote access to a set of fully autonomous mobile robots placed in a restricted area with dynamically reconfigurable obstacles, which enables solving a huge variety of problems. A user is able to control the robots in real time by their own developed algorithms as well as being able to analyze gathered data and observe activity of the robots by provided interfaces. The system is currently used for education at the Czech Technical University in Prague, Prague, Czech Republic, and at the University of Buenos Aires, Buenos, Aires, Argentina, and it is freely accessible to other institutions. In addition to the system overview, this paper presents the experience gained from the actual deployment of the system in teaching activities.
The Czech National Grid Infrastructure Chudoba, J; Křenková, I; Mulač, M ...
Journal of physics. Conference series,
10/2017, Volume:
898, Issue:
8
Journal Article
Peer reviewed
Open access
The Czech National Grid Infrastructure is operated by MetaCentrum, a CESNET department responsible for coordinating and managing activities related to distributed computing. CESNET as the Czech ...National Research and Education Network (NREN) provides many e-infrastructure services, which are used by 94% of the scientific and research community in the Czech Republic. Computing and storage resources owned by different organizations are connected by fast enough network to provide transparent access to all resources. We describe in more detail the computing infrastructure, which is based on several different technologies and covers grid, cloud and map-reduce environment. While the largest part of CPUs is still accessible via distributed torque servers, providing environment for long batch jobs, part of infrastructure is available via standard EGI tools in EGI, subset of NGI resources is provided into EGI FedCloud environment with cloud interface and there is also Hadoop cluster provided by the same e-infrastructure.A broad spectrum of computing servers is offered; users can choose from standard 2 CPU servers to large SMP machines with up to 6 TB of RAM or servers with GPU cards. Different groups have different priorities on various resources, resource owners can even have an exclusive access. The software is distributed via AFS. Storage servers offering up to tens of terabytes of disk space to individual users are connected via NFS4 on top of GPFS and access to long term HSM storage with peta-byte capacity is also provided. Overview of available resources and recent statistics of usage will be given.
The Computing Center of the Institute of Physics (CC IoP) of the Czech Academy of Sciences serves a broad spectrum of users with various computing needs. It runs WLCG Tier-2 center for the ALICE and ...the ATLAS experiments; the same group of services is used by astroparticle physics projects the Pierre Auger Observatory (PAO) and the Cherenkov Telescope Array (CTA). OSG stack is installed for the NOvA experiment. Other groups of users use directly local batch system. Storage capacity is distributed to several locations. DPM servers used by the ATLAS and the PAO are all in the same server room, but several xrootd servers for the ALICE experiment are operated in the Nuclear Physics Institute in Řež, about 10 km away. The storage capacity for the ATLAS and the PAO is extended by resources of the CESNET - the Czech National Grid Initiative representative. Those resources are in Plzen and Jihlava, more than 100 km away from the CC IoP. Both distant sites use a hierarchical storage solution based on disks and tapes. They installed one common dCache instance, which is published in the CC IoP BDII. ATLAS users can use these resources using the standard ATLAS tools in the same way as the local storage without noticing this geographical distribution. Computing clusters LUNA and EXMAG dedicated to users mostly from the Solid State Physics departments offer resources for parallel computing. They are part of the Czech NGI infrastructure MetaCentrum with distributed batch system based on torque with a custom scheduler. Clusters are installed remotely by the MetaCentrum team and a local contact helps only when needed. Users from IoP have exclusive access only to a part of these two clusters and take advantage of higher priorities on the rest (1500 cores in total), which can also be used by any user of the MetaCentrum. IoP researchers can also use distant resources located in several towns of the Czech Republic with a capacity of more than 12000 cores in total.
The petroleum charge history of the Barrandian basin was investigated by analysing quartz and calcite and organic phases that occur in veins and fractures cutting dolerite sills within the Liteň ...Formation (Silurian). The geochemical characteristics of fluid inclusions trapped in vein quartz and calcite, vein bitumens and adjacent potential source rocks when combined with burial and thermal history data reflect the presence of at least three separate hydrocarbon charge episodes. Solid highly reflecting (
R
max
=
0.92–1.49%) bitumen provides information on the first and oldest episode of oil migration. The precursor oil was probably derived relatively early during diagenesis from nearby organic-rich sediments and was subsequently thermally altered to form the solid bitumen.
The liquid oil preserved within the fluid inclusions in vein quartz and calcite cements represents a second hydrocarbon charge that migrated after the cooling of the sill, at diagenetic temperatures between 73 and 150
°C. This migration event probably occurred during the peak burial of the strata, during or after the Variscan orogeny. The inclusion oil is moderately matured, non-biodegraded and most likely derived from lower Palaeozoic source rocks such as the enclosing Liteň formation and/or directly overlying Kopanina and Přídolí formations. The presence of low salinity (0.2–3.2
eq. wt. % NaCl) aqueous inclusions coexisting with oil inclusions, indicates that the hydrocarbon flow had a substantial aqueous component.
Brightly yellow-fluorescing, low-reflecting (
R
r
=
0.25 %) wax forming thin coatings on vein minerals herald the third and most recent pulse of hydrocarbons that migrated significantly after the peak heating of the strata. Indirect evidence suggests that this late-stage event may have been associated with the post-Palaeogene Alpine uplift of the basin that stimulated circulation of waxy oils and acid waters through the reactivated fractures.
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7.
IPv6 Security Babik, M; Chudoba, J; Dewhurst, A ...
Journal of physics. Conference series,
10/2017, Volume:
898, Issue:
10
Journal Article
Peer reviewed
Open access
IPv4 network addresses are running out and the deployment of IPv6 networking in many places is now well underway. Following the work of the HEPiX IPv6 Working Group, a growing number of sites in the ...Worldwide Large Hadron Collider Computing Grid (WLCG) are deploying dual-stack IPv6/IPv4 services. The aim of this is to support the use of IPv6-only clients, i.e. worker nodes, virtual machines or containers. The IPv6 networking protocols while they do contain features aimed at improving security also bring new challenges for operational IT security. The lack of maturity of IPv6 implementations together with the increased complexity of some of the protocol standards raise many new issues for operational security teams. The HEPiX IPv6 Working Group is producing guidance on best practices in this area. This paper considers some of the security concerns for WLCG in an IPv6 world and presents the HEPiX IPv6 working group guidance for the system administrators who manage IT services on the WLCG distributed infrastructure, for their related site security and networking teams and for developers and software engineers working on WLCG applications.
The fraction of Internet traffic carried over IPv6 continues to grow rapidly. IPv6 support from network hardware vendors and carriers is pervasive and becoming mature. A network infrastructure ...upgrade often offers sites an excellent window of opportunity to configure and enable IPv6. There is a significant overhead when setting up and maintaining dual-stack machines, so where possible sites would like to upgrade their services directly to IPv6 only. In doing so, they are also expediting the transition process towards its desired completion. While the LHC experiments accept there is a need to move to IPv6, it is currently not directly affecting their work. Sites are unwilling to upgrade if they will be unable to run LHC experiment workflows. This has resulted in a very slow uptake of IPv6 from WLCG sites. For several years the HEPiX IPv6 Working Group has been testing a range of WLCG services to ensure they are IPv6 compliant. Several sites are now running many of their services as dual-stack. The working group, driven by the requirements of the LHC VOs to be able to use IPv6-only opportunistic resources, continues to encourage wider deployment of dual-stack services to make the use of such IPv6-only clients viable. This paper presents the working group's plan and progress so far to allow sites to deploy IPv6-only CPU resources. This includes making experiment central services dual-stack as well as a number of storage services. The monitoring, accounting and information services that are used by jobs also need to be upgraded. Finally the VO testing that has taken place on hosts connected via IPv6-only is reported.
We report a measurement of the energy spectrum of cosmic rays for energies above 2.5 × 1018 eV based on 215,030 events recorded with zenith angles below 60°. A key feature of the work is that the ...estimates of the energies are independent of assumptions about the unknown hadronic physics or of the primary mass composition. The measurement is the most precise made hitherto with the accumulated exposure being so large that the measurements of the flux are dominated by systematic uncertainties except at energies above 5 × 1019 eV. The principal conclusions are (1) The flattening of the spectrum near 5 × 1018 eV, the so-called "ankle," is confirmed. (2) The steepening of the spectrum at around 5 × 1019 eV is confirmed. (3) A new feature has been identified in the spectrum: in the region above the ankle the spectral index γ of the particle flux ( ∝ E−γ ) changes from 2.51 ± 0.03 ( stat ) ± 0.05 ( syst ) to 3.05 ± 0.05 ( stat ) ± 0.10 ( syst ) before changing sharply to 5.1 ± 0.3 ( stat ) ± 0.1 ( syst ) above 5 × 1019 eV. (4) No evidence for any dependence of the spectrum on declination has been found other than a mild excess from the Southern Hemisphere that is consistent with the anisotropy observed above 8 × 1018 eV.
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We report a measurement of the energy spectrum of cosmic rays above 2.5 × 1018 eV based on 215 030 events. New results are presented: at about 1.3 × 1019 eV , the spectral index changes from 2.51 ± ...0.03 (stat) ± 0.05 (syst) to 3.05 ± 0.05 (stat) ± 0.10 (syst), evolving to 5.1 ± 0.3 (stat) ± 0.1 (syst) beyond 5 × 1019 eV, while no significant dependence of spectral features on the declination is seen in the accessible range. These features of the spectrum can be reproduced in models with energy-dependent mass composition. The energy density in cosmic rays above 5 × 1018 eV is 5.66 ± 0.03 (stat) ± 1.40 (syst) × 1053 erg Mpc−3.
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