Abstract
The ToASt ASIC is a 64 channel integrated circuit designed for the readout of the double-sided silicon strip sensors that will equip the micro-vertex detector of the PANDA experiment. The ...ToASt ASIC operates with a 160 MHz clock, which defines also the time resolution. A common time stamp is distributed to all channels to provide a common time reference for time of arrival and time over threshold measurements. Two 160 Mb/s serial lines provide the interface to the data concentrator. ToASt is implemented in a commercial 110 nm CMOS technology with triplicated logic to protect against single event upsets.
Abstract
The PANDA (antiProton ANnihilation at DArmstadt) experiment will study the strong interaction in annihilation reactions between an antiproton beam and a stationary cluster jet target. The ...PANDA detector will be composed of several sub-detectors designed for tracking, particle identification and calorimetry. The Micro-Vertex Detector (MVD) is the innermost part of the tracking system surrounding the interaction region, which is designed for precise vertex and tracking detection. It consists of silicon pixel and double-sided microstrip detectors. For the readout of the microstrip sensors an ASIC called ToASt (Torino Asic for Strip readout) is being developed in 0.11 μm CMOS technology at INFN Turin. The ASIC takes advantage of both Time-over-Threshold and Time-of-Arrival methods to accurately measure the event's energy and timestamp. To sustain the acquisition of the microstrip sensors a MDC (Module Data Concentrator) ASIC is under development at KIT. Up to eight ToASt front-ends' data streams are multiplexed, read out and processed by one MDC. The data of several MDCs are collected and processed by the off-detector readout card MMB (MVD Multiplexer Board), also under development at KIT. The processed data is then transferred via 100 GbE optical links to the computing nodes. The ToASt chips have been integrated with the FPGA implementation of the MDC to form the first fully functional detector module. Beam tests have been performed at the COSY facility in Jülich. This paper focuses on the design of MDC ASIC and MMB board, the integration with the ToASt and presents preliminary beam test results.
This work presents a customized 110 nm CMOS process on high-resistivity substrate tailored for the production of fully-depleted pixel sensors. Starting from n-type substrates, customized surface ...implantations have been introduced to enable fast and efficient collection of the charge generated by ionizing particles or radiation. Double-sided processing has been used to define the backside electrode and the termination structures needed to bias the sensors at high voltage. A first run showing the feasibility of 300 μm-thick fully-depleted sensors was completed, and several test devices designed for the assessment of the process were fabricated together with a 24×24 pixels array with 50 μm pitch. The main technological challenges and the customization of the process are discussed, and electrical measurements on test devices demonstrating the functionality of the termination structures, the full depletion of the substrate and the fast charge collection are presented.
A 64-channel mixed-mode ASIC, suitable for particle detectors of large dynamic range and high capacitance up to hundreds of pF, is presented here. Each channel features an analogue front-end for ...signal amplification and filtering, and a mixed signal back-end to digitise and store the signal information. The analogue part consists of a low input-impedance programmable gain pre-amplifier based on a regulated common-gate (RCG) input stage, two shapers optimised for time and energy measurements. The back-end part mainly includes discriminators, TDCs and ADCs, which are used to process the signal and encode both the time of arrival and the charge in the input signal with a fully digital output. The programmable gain of the front-end (up to 400 fC input dynamic range) and the versatile back-end allow the readout of different gaseous detectors like GEM, MicroMEGAS and MWPC. The ASIC is designed for an event rate up to 100 kHz per channel and a power consumption less than 9 mW/channel, has been fabricated in a 110 nm CMOS technology.
Histone deacetylases (HDACs) play a key role in the regulation of gene expression and chromatin structure, and drugs targeting these enzymes might have an important impact in the treatment of human ...cancer. Herein, we report the characterization of (1H)-pyrroles as a new subfamily of HDAC inhibitors obtained by computational modeling of class-I human HDACs. From a functional standpoint, (1H)-pyrroles are powerful inductors of acetylation of histones H3 and H4, and restore the expression of growth-inhibitory genes. From a cellular view, these compounds cause a marked decrease in the viability of cancer cells in vitro and in vivo, associated with a cell-cycle arrest at G2/M and an inhibition of angiogenesis. Thus, (1H)-pyrroles emerge as a novel group of HDAC inhibitors with promising antitumoral features.
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DOBA, EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, IZUM, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UILJ, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
Computational calculations represent a very useful tool to study separately the occurrence of thermal and non-thermal effects of microwave irradiation through the determination of the thermodynamic ...and kinetic parameters of the reaction. In this paper, we approach the computational study of two previously reported cycloaddition reactions. All of the outcomes indicate the presence of a thermal effect alone for the microwave irradiation that produces changes in the regioselectivity or in the reaction mechanism.
The aim of this work is to gain an understanding of the heterogeneity of the customers of service firms dedicated to personal care. This comes from their participation in the value co-creation ...process. We later analyze if the distribution of the satisfaction variable is the same between the previously-identified groups. This analysis is carried out via a latent class segmentation. The empirical research data was obtained from a sample of users of firms from the Spanish sector of hairdressing and aesthetics. This is mostly made up of young, self-employed entrepreneurs and microenterprises. 547 questionnaires were correctly completed and included in the study. The use of the customers’ involvement in value co-creating as a segmentation criteria resulted in the users being put into two groups. It was thus verified that there are differences in the distribution of the satisfaction variable between the two groups studied. The main contribution of the study stems from considering the value co-creation behavior as a valid criterion for the segmentation of customers of aesthetics and personal care services. This facilitates the decision-making related to the marketing policies of the firms in the sector.
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CEKLJ, EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
8.
The quantum Arnold transformation Aldaya, V; Cossío, F; Guerrero, J ...
Journal of physics. A, Mathematical and theoretical,
02/2011, Volume:
44, Issue:
6
Journal Article
Peer reviewed
Using a quantum version of the Arnold transformation of classical mechanics, all quantum dynamical systems whose classical equations of motion are non-homogeneous linear second-order ordinary ...differential equations, including systems with friction linear in velocity, can be related to the quantum free-particle dynamical system. This transformation provides a basic (Heisenberg-Weyl) algebra of quantum operators, along with well-defined Hermitian operators which can be chosen as evolution-like observables and complete the entire Schrodinger algebra. It also proves to be very helpful in performing certain computations quickly, to obtain, for example, wavefunctions and closed analytic expressions for time-evolution operators.
Harmonic states for the free particle Guerrero, J; López-Ruiz, F F; Aldaya, V ...
Journal of physics. A, Mathematical and theoretical,
11/2011, Volume:
44, Issue:
44
Journal Article
Peer reviewed
Different families of states, which are solutions of the time-dependent free Schrodinger equation, are imported from the harmonic oscillator using the quantum Arnold transformation introduced in ...Aldaya et al (2011 J. Phys. A: Math. Theor. 44 065302). Among them, infinite series of states are given that are normalizable, expand the whole space of solutions, are spatially multi-localized and are eigenstates of a suitably defined number operator. Associated with these states new sets of coherent and squeezed states for the free particle are defined representing traveling, squeezed, multi-localized wave packets. These states are also constructed in higher dimensions, leading to the quantum mechanical version of the Hermite-Gauss and Laguerre-Gauss states of paraxial wave optics. Some applications of these new families of states and procedures to experimentally realize and manipulate them are outlined.
The earthen architectural heritage and, in general, the built ensembles integrating the so called "vernacular architecture", have been repeatedly investigated for more than a century by ...archaeologists, architects, ethnologists, historians or geographers. During the last thirty years we can find a significant progress in the procedures for studying, cataloguing, protecting and watching over these cultural goods, which are representative of the diverse ways of inhabiting and constructing in the different regions of the world. However, currently there are few interventions in this kind of heritage that one can consider truly scientific, which is even more obvious in the case of the earthen buildings. In fact, the earth-built architectural heritage is one of the most fragile and endangered sections in the vernacular heritage, regardless of what we find barely developed up to now the essential intervention criteria. To go in depth regarding the essential features of this kind of architecture, identify its main values as cultural landscape shaper and emphasize the most important historiographical contributions on the subject are the main goals of this paper.
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