ABSTRACT
Blazar S5 0716+714 is well-known for its short-term variability, down to intraday time-scales. We here present the 2-min cadence optical light curve obtained by the TESS space telescope in ...2019 December–2020 January and analyse the object fast variability with unprecedented sampling. Supporting observations by the Whole Earth Blazar Telescope Collaboration in B, V, R, and I bands allow us to investigate the spectral variability during the TESS pointing. The spectral analysis is further extended in frequency to the UV and X-ray bands with data from the Neil Gehrels Swift Observatory. We develop a new method to unveil the shortest optical variability time-scales. This is based on progressive de-trending of the TESS light curve by means of cubic spline interpolations through the binned fluxes, with decreasing time bins. The de-trended light curves are then analysed with classical tools for time-series analysis (periodogram, autocorrelation, and structure functions). The results show that below 3 d there are significant characteristic variability time-scales of about 1.7, 0.5, and 0.2 d. Variability on time-scales $\lesssim 0.2$ d is strongly chromatic and must be ascribed to intrinsic energetic processes involving emitting regions, likely jet substructures, with dimension less than about 10−3 pc. In contrast, flux changes on time-scales $\gtrsim 0.5$ d are quasi-achromatic and are probably due to Doppler factor changes of geometric origin.
Highlights • Nowadays there are no specific indicators for IMRT//IGRT Radiotherapy techniques. • Two structure, 10 processe and 2 outcome QIs were elaborated. • Data from four Italian Centers were ...collected and used for validation. • Seven indicators were completely new. A new standard is proposed for four indicators.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK, ZRSKP
Purpose and objective
To test the hypothesis that a rectal and bladder preparation protocol is associated with an increase in prostate cancer specific survival (PCSS), clinical disease free survival ...(CDFS) and biochemical disease free survival (BDFS).
Patients and methods
From 1999 to 2012, 1080 prostate cancer (PCa) patients were treated with three-dimensional conformal radiotherapy (3DCRT). Of these patients, 761 were treated with an empty rectum and comfortably full bladder (RBP) preparation protocol, while for 319 patients no rectal/bladder preparation (NRBP) protocol was adopted.
Results
Compared with NRBP patients, patients with RBP had significantly higher BDFS (64% vs 48% at 10 years, respectively), CDFS (81% vs 70.5% at 10 years, respectively) and PCSS (95% vs 88% at 10 years, respectively) (log-rank test
p
< 0.001). Multivariate analysis (MVA) indicated for all treated patients and intermediate high-risk patients that the Gleason score (GS) and the rectal and bladder preparation were the most important prognostic factors for PCSS, CDFS and BDFS. With regard to high- and very high-risk patients, GS, RBP, prostate cancer staging and RT dose were predictors of PCSS, CDFS and BDFS in univariate analysis (UVA).
Conclusion
We found strong evidence that rectal and bladder preparation significantly decreases biochemical and clinical failures and the probability of death from PCa in patients treated without daily image-guided prostate localization, presumably since patients with RBP are able to maintain a reproducibly empty rectum and comfortably full bladder across the whole treatment compared with NRPB patients.
The GAPS Programme with HARPS-N at TNG Barbato, D.; Sozzetti, A.; Biazzo, K. ...
Astronomy and astrophysics (Berlin),
2019, 20190101, Volume:
621
Journal Article
Peer reviewed
Open access
Context. Statistical studies of exoplanets have shown that giant planets are more commonly hosted by metal-rich dwarf stars than low-metallicity stars, while no such correlation is evident for lower ...mass planets. The search for giant planets around metal-poor stars and the estimate of their occurrence fp is an important element in providing support to models of planet formation. Aims. We present results from the HARPS-N search for giant planets orbiting metal-poor (− 1.0 ≤Fe/H ≤−0.5 dex) stars in the northern hemisphere, complementing a previous HARPS survey on southern stars in order to update the estimate of fp. Methods. High-precision HARPS-N observations of 42 metal-poor stars were used to search for planetary signals to be fitted using differential evolution Markov chain Monte Carlo single-Keplerian models. We then joined our detections to the results of the previous HARPS survey on 88 metal-poor stars to provide a preliminary estimate of the two-hemisphere fp. Results. We report the detection of two new giant planets around HD 220197 and HD 233832. The first companion has M sin i = 0.20−0.04+0.07$\sin{i}=0.20_{-0.04}^{+0.07}$sini=0.20−0.04+0.07 MJup and an orbital period of 1728−80+162 $1728_{-80}^{+162}$1728−80+162 days, and for the second companion, we find two solutions of equal statistical weight with periods of 2058−40+47 $2058_{-40}^{+47}$2058−40+47 and 4047−117+91 $4047_{-117}^{+91}$4047−117+91 days and minimum masses of 1.78−0.06+0.08 $1.78_{-0.06}^{+0.08}$1.78−0.06+0.08 and 2.72−0.23+0.23 $2.72_{-0.23}^{+0.23}$2.72−0.23+0.23 MJup, respectively. Joining our two detections with the three from the southern survey, we obtain a preliminary and conservative estimate of the global frequency of fp = 3.84 −1.06+2.45% $f_p=3.84_{-1.06}^{+2.45}\%$fp=3.84−1.06+2.45% for giant planets around metal-poor stars. Conclusions. The two new giant planets orbit dwarf stars at the metal-rich end of the HARPS-N metal-poor sample. This corroborates previous results that suggested that giant planet frequency is still a rising function of the host star Fe/H. We also note that all detections in the overall sample are giant long-period planets.
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