We report a branching fraction measurement of the singly Cabibbo-suppressed decay Λ+c → ΛK+ using a data sample collected with the BESIII detector at the BEPCII storage ring. The data span ...center-of-mass energies from 4.599 to 4.950 GeV and correspond to an integrated luminosity of 6.44 fb −1 . The branching fraction of Λ+c → ΛK+ relative to that of the Cabibbo-favored decay Λ+c → Λπ+ is measured to be R = B(Λ+c → ΛK+) / B(Λ+c → Λπ+) = (4.78±0.34±0.20)%. Combining with the world-average value of B(Λ+c → Λπ+), we obtain B(Λ+c → ΛK+) = (6.21±0.44±0.26±0.34) × 10 −4 . Here the first uncertainties are statistical, the second systematic, and the third comes from the uncertainty of the Λ+c→Λπ+ branching fraction. This result, which is more precise than previous measurements, does not agree with theoretical predictions, and suggests that nonfactorizable contributions have been underestimated in current models.
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A
bstract
Using (10087 ± 44) × 10
6
J
/
ψ
events collected with the BESIII detector at the BEPCII
e
+
e
−
storage ring at the center-of-mass energy of
s
= 3.097 GeV, we present a search for the rare ...semi-muonic charmonium decay
J
/
ψ
→
D
−
μ
+
ν
μ
+ c.c.. Since no significant signal is observed, we set an upper limit of the branching fraction to be
B
(
J
/
ψ
→
D
−
μ
+
ν
μ
+ c.c.) < 5.6 × 10
−
7
at 90% confidence level. This is the first search for the weak decay of charmonium with a muon in the final state.
The singly Cabibbo suppressed decay Λ + c → pη′ is measured using 4.5 fb −1 of e + e − collision data collected at center-of-mass energies between 4.600 and 4.699 GeV with the BESIII detector at ...BEPCII. Evidence for Λ + c → pη′ with a statistical significance of 3.6σ is reported with a double-tag approach. The Λ + c → pη′ absolute branching fraction is determined to be (5.62 +2.46 −2.04 ±0.26)×10 −4 , where the first and second uncertainties are statistical and systematic, respectively. Our result is consistent with the branching fraction obtained by the Belle collaboration within the uncertainty of 1σ.
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To cite this article: Chen X, Song C‐H, Liu Z‐Q, Feng B‐S, Zheng P‐Y, Li P, In SH, Tang S‐G, Yang P‐C. Intestinal epithelial cells express galectin‐9 in patients with food allergy that plays a ...critical role in sustaining allergic status in mouse intestine. Allergy 2011; 66: 1038–1046.
Background and aims: Mechanisms in sustaining the allergic hypersensitivity status in the body are unclear. Galectin‐9 (Gal‐9) has strong immune regulatory capacity. The present study aims to elucidate the role of Gal‐9 in sustaining allergic status in the intestine.
Methods: Duodenal biopsies were obtained from 20 patients with peptic ulcer and food allergy (FA). The expression of Gal‐9 in intestinal tissue was examined at both protein level and mRNA level. Two coculture systems with intestinal epithelial cells (IEC) and mast cells, or dendritic cells (DC) and T cells were established to investigate the source of Gal‐9 in the intestine and the mechanism by which Gal‐9 modulated DC’s phenotyping and sustained the T helper 2 polarization.
Results: Normal IEC showed mild expression of Gal‐9 that was markedly enhanced in patients with FA. Mast cells had the capability to induce IEC to produce Gal‐9 via releasing tryptase that activated the proteinase‐activated receptor 2 on IEC. Gal‐9 activated DC to produce TIM4 (T‐cell immunoglobulin mucin domain) via ligating TIM3 on DC via activating the cyclic guanosine monophosphate (cGMP) pathway. In a mouse FA model, blocking Gal‐9 inhibited the allergic hypersensitivity status and the antigen‐specific Th2 response in the intestine.
Conclusions: IEC‐derived Gal‐9 contributes to sustaining the allergic status in the intestine.
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BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SAZU, SBCE, SBMB, UL, UM, UPUK
A search for a massless dark photon gamma' is conducted using 4.5 fb(-1) of e(+)e(-) collision data collected at center-of-mass energies between 4.600 and 4.699 GeV with the BESIII detector at ...BEPCII. No significant signal is observed, and the upper limit on the branching fraction B(Lambda(+)(c) -> p gamma') is determined to be 8.0 x 10(-5) at 90% confidence level.
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Summary
The association between potential long‐term effects of previous schistosome infection (PSI) and the development of metabolic syndrome remains unknown. Therefore, we aimed to evaluate the ...association between them. Participants were from regions which were all reportedly heavily endemic for S. japonicum in China 40 years ago. One thousand five hundred and ninety‐seven men were enrolled. Among these, 465 patients with PSI were selected as study subjects and 1132 subjects served as controls. We found PSI significantly correlated with lower prevalences of metabolic syndrome and its components, including central obesity, hypertriglyceridemia and low high‐density lipoprotein cholesterol, which indicates that the potential long‐term effects of PSI may reduce the risk of metabolic syndrome. However, further studies are needed to investigate the protective immune effects of PSI.
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DOBA, FZAB, GIS, IJS, IZUM, KILJ, NLZOH, NUK, OILJ, PILJ, PNG, SAZU, SBCE, SBMB, SIK, UILJ, UKNU, UL, UM, UPUK
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