Ozone is a powerful oxidant that is increasingly used as sanitizing agent in the wine industry and even in the vineyard to control grapevine diseases. In this study, we evaluated the effect on grape ...enological quality of ozonated water spraying treatments carried out in Bobal grapevines during two consecutive harvest seasons. In the first season, ozonated water was applied once during the ripening period on grapevines trained on the traditional gobelet system (S1). In the second season, ozonated water was applied three times between the fruit set and harvest on grapevines grown on a vertical trellis system (S2). Grape quality on harvest day was evaluated through several enological and chromatic parameters, the phenolic maturity, the Varietal Aroma Potential Index (IPAv) and the phenolic and volatile composition. The S1 treatment had a positive effect on the technological maturity, the chromatic parameters, the seed maturity and the content of glycosylated aroma precursors, phenolic compounds and free terpenoids of grapes. The S2 treatment also improved the technological maturity and the content of total anthocyanins (pH 1.0) and free terpenoids, but had a negative impact on the chromatic parameters, the anthocyanin extractability and the content of glycosylated aroma precursors and phenolic compounds. Therefore, ozonated water sprayed on Bobal grapevines affected the quality of grapes, but the effect seemed to depend on the number of applications.
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•Spraying ozonated water on Bobal grapevines affects grape quality.•Ozonated water increases the content of terpenoids and total anthocyanins (pH 1.0) of grapes.•A one-time application during the ripening period improves the overall grape quality.•Three applications before harvest have a negative impact on colour and phenolics.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
This paper explores the possibility to measure changes in internal stress in ferromagnetic steels using magnetostatic methods. The device consists of a permanent magnet placed close to the steel ...piece and a magnetic probe between both elements. The magnetostatic field measured by using the probe is partially due to the magnetization of the steel piece. Internal stress variations in the steel alter its magnetic permeability due to the magnetoelastic effect, varying the magnetostatic field measured by using the probe. For the device we present here, the relative variation of the measured magnetic field is of the order of 1.7 × 10−5/MPa of internal stress.
Background
There are few data on the epidemiology of infections caused by
Streptococcus bovis
(Sb). Some studies suggest that both residence in rural areas and contact with livestock could be ...potential risk factors.
Methods
We performed a retrospective study for the period 2005–2016 of all cases of bacteremia caused by Sb in Galicia (a region in the northwest of Spain). The association between the incidence rate of Sb bacteremia and the number of cattle by province and district was analyzed.
Results
677 cases were included with a median age of 76 years, 69.3% males. The most frequent infections were endocarditis (234 cases, 34.5%), primary bacteremia (213 cases, 31.5%) and biliary infection (119 cases, 17.5%). In 252 patients, colon neoplasms were detected (37.2%).
S. gallolyticus
subsp.
gallolyticus
was the predominant species (52.3%). Mortality was 15.5% (105 cases). The annual incidence rate was 20.2 cases/10
6
inhabitants and was correlated with the density of cattle (
p
< 0.001), but not with rurality. When comparing the two provinces with a strong predominance of rural population, but with important differences in the number of cattle, such as Orense and Lugo, with 6% and 47.7% of Galician cattle, respectively, the rates were very different: 15.8 and 43.6 cases/10
6
, respectively, with an RR of 2.7 (95% CI, 2.08–3.71). Some districts of the province of Lugo had rates higher than 100 cases/10
6
inhabitants.
Conclusions
Our study shows a significant correlation between the rates of Sb bacteremia and cattle density, suggesting a possible transmission of Sb from cows to people.
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EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OBVAL, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
Background and purpose: The question whether patients with essential tremor (ET) have slowed movements as part of their clinical manifestations is still a matter of controversy. We analyzed basic ...motor function in patients with ET and in healthy matched controls.
Methods: We studied 61 patients with ET and 122 age‐ and sex‐matched controls. Evaluation included four timed tests (pronation‐supination, finger tapping and movement between two points, all with both hands, and walking test); and three tests performed on a personal computer (speed for pressing repetitively a key – frequency, visual reaction time and movement time, all with both hands).
Results: Essential tremor patients showed higher mean values for right and left finger tapping, left movement between two points; and with right and left frequency and reaction time. In the logistic regression study, ET patients showed significantly higher values than controls for right and left finger tapping; mean, SD, maximum and rank values of right and left frequency; and mean, SD, minimum, maximum and rank values of right and left visual reaction time. Tremor severity was not correlated with the altered values.
Conclusions: Patients with ET showed impaired motor performance, at least in some tasks, such as rapid repetitive finger movements (finger tapping and frequency) and visual reaction time (impairment was not related with tremor severity). This probably means that patients with ET have some degree of bradykinesia.
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BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SBCE, SBMB, UL, UM, UPUK
► A MARS model is used as a predictive model of cyanotoxins presence. ► Cyanobacterial HABs are dangerous for people and the environment in fresh waters. ► The influence of the different variables in ...this process is studied in detail.
There is an increasing need to describe cyanobacteria blooms since some cyanobacteria produce toxins, termed cyanotoxins. These latter can be toxic and dangerous to humans as well as other animals and life in general. It must be remarked that the cyanobacteria are reproduced explosively under certain conditions. This results in algae blooms, which can become harmful to other species if the cyanobacteria involved produce cyanotoxins. In this research work, the evolution of cyanotoxins in Trasona reservoir (Principality of Asturias, Northern Spain) was studied with success using the data mining methodology based on multivariate adaptive regression splines (MARS) technique. The results of the present study are two-fold. On one hand, the importance of the different kind of cyanobacteria over the presence of cyanotoxins in the reservoir is presented through the MARS model and on the other hand a predictive model able to forecast the possible presence of cyanotoxins in a short term was obtained. The agreement of the MARS model with experimental data confirmed the good performance of the same one. Finally, conclusions of this innovative research are exposed.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
36.
Quantum computing with graphene plasmons Alonso Calafell, I.; Cox, J. D.; Radonjić, M. ...
npj quantum information,
05/2019, Volume:
5, Issue:
1
Journal Article
Peer reviewed
Open access
Abstract
Among the various approaches to quantum computing, all-optical architectures are especially promising due to the robustness and mobility of single photons. However, the creation of the ...two-photon quantum logic gates required for universal quantum computing remains a challenge. Here we propose a universal two-qubit quantum logic gate, where qubits are encoded in surface plasmons in graphene nanostructures, that exploits graphene's strong third-order nonlinearity and long plasmon lifetimes to enable single-photon-level interactions. In particular, we utilize strong two-plasmon absorption in graphene nanoribbons, which can greatly exceed single-plasmon absorption to create a “square-root-of-swap” that is protected by the quantum Zeno effect against evolution into undesired failure modes. Our gate does not require any cryogenic or vacuum technology, has a footprint of a few hundred nanometers, and reaches fidelities and success rates well above the fault-tolerance threshold, suggesting that graphene plasmonics offers a route towards scalable quantum technologies.
Context.
55 Cnc e is a transiting super-Earth (radius 1.88
R
⊕
and mass 8
M
⊕
) orbiting a G8V host star on a 17-h orbit.
Spitzer
observations of the planet’s phase curve at 4.5 μm revealed a ...time-varying occultation depth, and MOST optical observations are consistent with a time-varying phase curve amplitude and phase offset of maximum light. Both broadband and high-resolution spectroscopic analyses are consistent with either a high mean molecular weight atmosphere or no atmosphere for planet e. A long-term photometric monitoring campaign on an independent optical telescope is needed to probe the variability in this system.
Aims.
We seek to measure the phase variations of 55 Cnc e with a broadband optical filter with the 30 cm effective aperture space telescope CHEOPS and explore how the precision photometry narrows down the range of possible scenarios.
Methods.
We observed 55 Cnc for 1.6 orbital phases in March of 2020. We designed a phase curve detrending toolkit for CHEOPS photometry which allowed us to study the underlying flux variations in the 55 Cnc system.
Results.
We detected a phase variation with a full-amplitude of 72 ± 7 ppm, but did not detect a significant secondary eclipse of the planet. The shape of the phase variation resembles that of a piecewise-Lambertian; however, the non-detection of the planetary secondary eclipse, and the large amplitude of the variations exclude reflection from the planetary surface as a possible origin of the observed phase variations. They are also likely incompatible with magnetospheric interactions between the star and planet, but may imply that circumplanetary or circumstellar material modulate the flux of the system.
Conclusions.
This year, further precision photometry of 55 Cnc from CHEOPS will measure variations in the phase curve amplitude and shape over time.
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FMFMET, NUK, UL, UM, UPUK
Scleroderma-like syndrome due to hydroxyurea García-Martínez, F. J.; García-Gavín, J.; Álvarez-Pérez, A. ...
Clinical and experimental dermatology,
October 2012, Volume:
37, Issue:
7
Journal Article
Peer reviewed
Summary
Scleroderma‐like cutaneous changes have been reported in association with several drugs, but not with hydroxyurea (HU), to our knowledge. We report the case of a 67‐year‐old man who was ...treated with HU (hydroxycarbamide) for 12 years for a myeloproliferative disorder, and presented a progressive pruritic woody induration, symmetrically affecting both legs. He also had Gottron‐like papules on the back of the metacarpophalangeal joints, and a retroauricular undifferentiated squamous cell carcinoma. On histological examination of a skin biopsy taken from the leg, massive dermal fibrosis was seen, with thickening of collagen bundles throughout the entire dermis. Six months after HU withdrawal, the skin induration resolved without scarring. Scleroderma‐like syndrome has not been previously considered one of the secondary effects of HU. The evolution of our patient’s condition supports a causal relationship between the HU treatment and the sclerodermiform changes of the skin.
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BFBNIB, DOBA, FZAB, GIS, IJS, IZUM, KILJ, NLZOH, NUK, OILJ, PILJ, PNG, SAZU, SBCE, SBMB, SIK, UILJ, UKNU, UL, UM, UPUK
•A novel methodology to characterize voice diseases using nonlinear dynamics.•Use of complexity measures based on the analysis of the time delay embedded space.•Transformation of the feature space ...using a Discrete Hidden Markov Model.•The methodology validated on three different datasets with different voice diseases.
This work describes a novel methodology to characterize voice diseases by using nonlinear dynamics, considering different complexity measures that are mainly based on the analysis of the time delay embedded space. The feature space is represented with a DHMM and a further transformation of the DHMM states to a hyperdimensional space is performed. The discrimination between healthy and pathological speech signals is peformed by using a RBF-SVM which is trained following a K-fold cross-validation strategy. Results of around 99% of accuracy are obtained for three different voice disorders, disphonia due to laryngeal pathologies, hypernasality due to cleft lip and palate, and dysarthria due to Parkinson's disease.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK, ZRSKP
Mannheimia haemolytica
causes respiratory disease in cattle. Amyloid proteins are a major component of biofilms; they aid in adhesion and confer resistance against several environmental insults. The ...amyloid protein curli is highly resistant to protease digestion and physical and chemical denaturation and binds Congo red (CR) dye. The purpose of this study was to characterize an approximately 50-kDa CR-binding amyloid-like protein (ALP) expressed by
M. haemolytica
. This protein resisted boiling and formic acid digestion and was recognized by a polyclonal anti-
Escherichia coli
curli serum, suggesting its relationship with amyloid proteins. Immunolabeling and transmission electron microscopy showed that antibodies bound long, thin fibers attached to the bacterial surface. Mass spectrometry analysis indicated that these fibers are
M. haemolytica
OmpP2-like proteins. The purified protein formed filaments in vitro, and antiserum against it reacted positively with biofilms. An in silico analysis of its amino acid sequence indicated it has auto-aggregation properties and eight amyloid peptides. Rabbit polyclonal antibodies generated against this ALP diminished the adhesion of ATCC 31612 and BA1
M. haemolytica
strains to A549 human epithelial cells, indicating its participation in cell adhesion. ALP expressed by
M. haemolytica
may be important in its pathogenicity and ability to form biofilms.
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EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OBVAL, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
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