Abstract
The Central Atlantic Magmatic Province (CAMP) is the most aerially extensive magmatic event in Earth’s history, but many questions remain about its origin, volume, and distribution. Despite ...many observations of CAMP magmatism near Earth’s surface, few constraints exist on CAMP intrusions at depth. Here we present detailed constraints on crustal and upper mantle structure from wide-angle seismic data across the Triassic South Georgia Rift that formed shortly before CAMP. Lower crustal magmatism is concentrated where synrift sedimentary fill is thickest and the crust is thinnest, suggesting that lithospheric thinning influenced the locus and volume of magmatism. The limited distribution of lower crustal intrusions implies modest total CAMP volumes of 85,000 to 169,000 km
3
beneath the South Georgia Rift, consistent with moderately elevated mantle potential temperatures (<1500 °C). These results suggest that CAMP magmatism in the South Georgia Rift is caused by syn-rift decompression melting of a warm, enriched mantle.
LLNL is involved with a number of TPC projects spanning basic science to homeland security. This talk outlines the TPC work at LLNL and specifically focuses on the neutron TPC.
Rossby waves are difficult to detect with
in situ methods. However, as we show in this paper, they can be clearly identified in multi-parameters in multi-mission satellite observations of sea surface ...height (SSH), sea surface temperature (SST) and ocean color observations of chlorophyll-
a (chl-
a), as well as 1/12° global HYbrid Coordinate Ocean Model (HYCOM) simulations of SSH, SST and sea surface salinity (SSS) in the Indian Ocean. While the surface structure of Rossby waves can be elucidated from comparisons of the signal in different sea surface parameters, models are needed to gain direct information about how these waves affect the ocean at depth. The first three baroclinic modes of the Rossby waves are inferred from the Fast Fourier Transform (FFT), and two-dimensional Radon Transform (2D RT). At many latitudes the first and second baroclinic mode Rossby wave phase speeds from satellite observations and model parameters are identified. Wavelet transforms of these multi-parameters from satellite observations and model simulations help to discriminate between the annual and semi-annual signal of these Rossby waves. This comprehensive study reveals that the surface signature of Rossby waves in SSS anomalies is likely to be between 0.05 and 0.3 psu in the South Indian Ocean.
Full text
Available for:
GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
SAX J2103.5+4545 has been continuously monitored for ∼900 d by the Rossi X-ray Timing Explorer (RXTE) since its outburst in 2002 July. Using these observations and previous archival RXTE observations ...of SAX J2103.5+4545, we refined the binary orbital parameters and find the new orbital period as P= (12.665 36 ± 0.000 88) d and the eccentricity as 0.4055 ± 0.0032. With these new orbital parameters, we constructed the pulse frequency and pulse frequency derivative histories of the pulsar and confirmed the correlation between X-ray flux and pulse frequency derivative presented by Baykal, Stark & Swank. We constructed the power spectra for the fluctuations of pulse frequency derivatives and found that the power-law index of the noise spectra is 2.13 ± 0.6. The power-law index is consistent with random walk in pulse frequency derivative and is the steepest among the HMXRBs. X-ray spectra analysis confirmed the inverse correlation trend between power-law index and X-ray flux found by Baykal et al.
Full text
Available for:
BFBNIB, FZAB, GIS, IJS, IZUM, KILJ, NLZOH, NUK, OILJ, PILJ, PNG, SAZU, SBCE, SBMB, UL, UM, UPUK
A combined lipidomics and transcriptomics analysis was performed on mouse myeloma SP2/0, Chinese hamster ovary (CHO), and human embryonic kidney (HEK) cells in order to compare widely used mammalian ...expression systems. Initial thin layer chromatography (TLC) analysis indicated that phosphatidylethanolamine (PE) and phosphatidylcholine (PC) were the major lipid components in all cell lines with lower amounts of sphingomyelin (SM) in SP2/0 compared to CHO and HEK, which was subsequently confirmed and expanded upon following mass spectrometry (MS) analysis. HEK contained 4–10-fold higher amounts of lyso phosphatidylethanolamine (LPE) and 2–4-fold higher amounts of lyso phosphatidylcholine (LPC) compared to SP2/0 and CHO cell lines. C18:1 followed by C16:1 were the main contributors to the difference in both LPE and LPC levels. Alternatively, the SP2/0 cell line exhibited 30–65-fold lower amounts of SM principally in the amount of 16:0. By mapping the transcriptomics data to KEGG pathways, we found expression levels of secretory phospholipase A2 (sPLA2), lysophospholipid acyltransferase (LPEAT), lysophosphatidylcholine acyltransferase (LPCAT), and lysophospholipase (LYPLA) can contribute to the differences in LPE and LPC. Sphingomyelin synthases (SMS) and sphingomyelin phosphodiesterase (SMase) enzymes may play roles in SM differences across the three cell lines. The results of this study provide insights that will aid the understanding of the physiological and secretory differences across recombinant protein production systems.
Full text
Available for:
IJS, KILJ, NUK, PNG, UL, UM
microRNAs with their ability to regulate complex pathways that control cellular behavior and phenotype have been proposed as potential targets for cell engineering in the context of optimization of ...biopharmaceutical production cell lines, specifically of Chinese Hamster Ovary cells. However, until recently, research was limited by a lack of genomic sequence information on this industrially important cell line. With the publication of the genomic sequence and other relevant data sets for CHO cells since 2011, the doors have been opened for an improved understanding of CHO cell physiology and for the development of the necessary tools for novel engineering strategies. In the present review we discuss both knowledge on the regulatory mechanisms of microRNAs obtained from other biological models and proof of concepts already performed on CHO cells, thus providing an outlook of potential applications of microRNA engineering in production cell lines.
Full text
Available for:
GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
Rossby waves have been well identified in satellite derived sea surface height (SSH), sea surface temperature (SST) and ocean color observations. Studies of Rossby waves have yet to include sea ...surface salinity (SSS) as a parameter, largely because presently available in situ measurements of salinity lack sufficient spatial and temporal coverage, and as of now no methods are available for measuring salinity from a satellite. In this paper, we demonstrate that Rossby waves can be observed in SSS in the Indian Ocean by using simulations of the 1/12° global Hybrid Coordinate Ocean Model (HYCOM). HYCOM results compared favorably to SSS data provided by Argo floats and the World Ocean Atlas 2005 (WOA05) in selected grid boxes in the Indian Ocean. Hovmöller diagrams of HYCOM SSS anomalies and gradient show the distinct westward propagating signature of Rossby waves, with a steeper slope in longitude/time plots further from the equator. The propagation speeds, calculated from a 2D Radon Transform are comparable with new theoretical speeds for Rossby waves. Annual westward propagating signals in the SSS simulations at most of the latitudes in the Indian Ocean coincide with previous studies. We hope that future studies of Rossby waves in SSS using model results and eventually satellite measurements of salinity data will allow a better understanding of Rossby wave dynamics.
Full text
Available for:
FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SAZU, SBCE, SBMB, UL, UM, UPUK
PDF
