Major challenges must be tackled for brain-computer interfaces to mature into an established communications medium for VR applications, which will range from basic neuroscience studies to developing ...optimal peripherals and mental gamepads and more efficient brain-signal processing techniques.
In this study, rainfall data are prepared at a 0.01° scale using 16-yr spaceborne radar data over the area of 36.13°S–36.13°N as provided by the Tropical Rainfall Measuring Mission (TRMM) ...Precipitation Radar (PR). A spatial resolution that is finer than the field of view is obtained by assuming rainfall uniformity within an instantaneous footprint centered on the PR footprint geolocation. These ultra-high-resolution data reveal local rainfall concentrations over slope areas. A new estimate of the maximum rainfall at Cherrapunji, India, was observed on the valley side, approximately 5 km east of the gauge station, and is approximately 50% higher than the value indicated by the 0.1°-scale data. A case study of Yakushima Island, Japan, indicates that several percent of the sampling error arising from the spatial mismatch may be contained in conventional 0.05°-scale datasets generated without footprint areal information. The differences attributable to the enhancement in the resolution are significant in complex terrain such as the Himalayas. The differences in rainfall averaged for the 0.1° and 0.01° scales exceed 10 mm day−1 over specific slope areas. In the case of New Guinea, the mean rainfall on a mountain ridge can be 30 times smaller than that on an adjacent slope at a distance of 0.25°; this is not well represented by other high-resolution datasets based on gauges and infrared radiometers. The substantial nonuniformity of rainfall climatology highlights the need for a better understanding of kilometer-scale geographic constraints on rainfall and retrieval approaches.
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The single-antenna gain calibration method was first proposed by Glimm et al. of Physikalisch-Technische Bundesanstalt in 1999. Their method requires the measurements of the reflection coefficient of ...an antenna under test (AUT) in free space and the reflection coefficient on a large metal plane using two different measurement setups. On the other hand, we proposed a new single-antenna gain calibration method that can measure these quantities using the same measurement setup. Our proposed method uses the average value of the reflection coefficients of the AUT for various distances from the large metal plane to the AUT. Furthermore, we established a measurement setup for our proposed single-antenna method for a double-ridged guide horn (DRGH) antenna in the frequency range from 1 to 6 GHz. To estimate the antenna gain, we applied the Friis transmission formula, which included the amplitude center distance of the antenna. By using our proposed method and the measurement setup, the expanded uncertainty (<inline-formula> <tex-math notation="LaTeX">k = 2 </tex-math></inline-formula>) of the DRGH was estimated to be from 0.61 to 1.70 dB over a frequency range from 1 to 6 GHz.
Time-optimal control theory provides recipes to achieve quantum operations with high fidelity and speed, as required in quantum technologies such as quantum sensing and computation. While technical ...advances have achieved the ultrastrong driving regime in many physical systems, these capabilities have yet to be fully exploited for the precise control of quantum systems, as other limitations, such as the generation of higher harmonics or the finite response time of the control apparatus, prevent the implementation of theoretical time-optimal control. Here we present a method to achieve time-optimal control of qubit systems that can take advantage of fast driving beyond the rotating wave approximation. We exploit results from time-optimal control theory to design driving protocols that can be implemented with realistic, finite-bandwidth control fields, and we find a relationship between bandwidth limitations and achievable control fidelity.
A seroprevalence survey on measles, mumps, rubella and varicella was conducted on healthcare workers (HCWs) at Shimane University Hospital, Japan utilizing an enzyme immunoassay. Of 1811 HCWs tested, ...91·8% were seropositive to measles, 92·1% to mumps, 89·5% to rubella and 96·3% to varicella. Sex-related differences in seroprevalence were found in rubella (males vs. females: 84·7 vs. 92·2%, P < 0·001). Moreover, males aged 30–39 years were most susceptible to rubella (22·4%), which may be attributed to the design of childhood immunization programmes in Japan. Individuals aged ⩽29 years were more susceptible to measles (14·3%) and mumps (10·9%), compared to other age groups. There were no significant sex- and age-related differences in varicella seroprevalence. The physician occupational group was more susceptible to rubella, but no significant occupational-related difference was observed in the other diseases. Susceptible subjects, with negative or equivocal serological results were given a vaccine which induced seroconversion in most vaccinees. Seroconversion occurred more frequently in the equivocal group than in the negative group. These findings provide a new insight for the seroprevalence survey of vaccine-preventable diseases in Japanese HCWs with special reference to vaccine efficacy.
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Local anesthetics suppress proliferation in several cancer cells. The mechanism of the suppression, however, is unknown. Our previous study shows that lidocaine, at the level of tissue concentration ...under topical or local administration, has a direct inhibitory effect on the activity of epidermal growth factor receptor (EGFR), which is a potential target for antiproliferation in cancer cells. Therefore, we hypothesized that lidocaine would suppress the proliferation of cancer cells through the inhibition of EGFR activity. We investigated the effects of lidocaine (40-4000 microM) on proliferation of a human tongue cancer cell line, CAL27, which has a high level of EGFR expression, and also examined the effect of lidocaine on epidermal growth factor (EGF)-stimulated autophosphorylation of EGFR in CAL27 cells. A clinical concentration of lidocaine (400 microM) suppressed both serum-induced and EGF-induced proliferation of CAL27 cells and inhibited EGF-stimulated tyrosine kinase activity of EGFR without cytotoxicity. A larger concentration of lidocaine (4000 microM) showed cytotoxicity with an antiproliferative effect. We suggest that the inhibition of EGF-stimulated EGFR activity is one of the mechanisms of the antiproliferative effect of lidocaine on CAL27 cells. Lidocaine administered topically within the oral cavity for cancer pain relief may suppress the proliferation of human tongue cancer cells.
The new species of Zanclea sango sp. nov. is described from Okinawajima Island, Ryukyu Archipelago, south-western Japan. The new hydrozoan species is associated with at least three scleractinian ...corals (Pavona divaricata, P. venosa and Psammocora contigua). Zanclea sango sp. nov. is a polymorphic hydroid and the hydrorhiza grows between the coral skeleton and calicoblastic ectoderm. The hydrocaulus and hydrorhiza are surrounded by perisarc. Newly released medusae are almost spherical, with four perradial exumbrellar nematocyst pouches including stenoteles, and two long marginal tentacles with cnidophores containing macrobasic euryteles. Zanclea sango sp. nov. is allied to Zanclea gilii Boero et al., 2000 and Zanclea margaritae Pantos & Bythell, 2010, but it is distinguished by its cnidome, the presence of a perisarc around hydrorhiza, and lower host-specificity. According to a hypothetical Zanclea phylogeny, the ancestral species of Zanclea had an opportunistic association with some benthic organisms, such as algae or bivalves, and its hydrorhiza was covered by a perisarc. Later, some species established specific associations with benthic animals, after which the hydrorhiza lost the perisarc and became directly covered with host tissue. Among Zanclea inhabiting corals, the present species, with multiple coral host species and a perisarc around the hydrorhiza, seems to retain more ancestral character states than Z. gilii and Z. margaritae, which have specific coral host species and no perisarc around the hydrorhiza.
As the prevalence of anorexia nervosa (AN) increased, surgery in severe AN patients also increased in the 2000s. We experienced a surgical case of a patient with severe AN, showing an extremely low ...BMI of 8.6 kg m−2. We investigated the problems associated with this case and propose criteria to manage severe AN. We endeavour to report on the perioperative management of rare and severe symptoms and surgical indications of severely malnourished patients.
All published reports were identified through comprehensive searches using PubMed, BioMedLib, and the Japan Medical Abstracts Society with the following terms and keywords: ‘anorexia nervosa’, ‘eating disorder’, ‘hypoglycaemia’, ‘leucocytopaenia’, ‘gelatinous bone marrow’, ‘surgery’, and ‘operation’. In cases of AN with a BMI under 13 kg m−2, marked hypoglycaemia, leucocytopaenia <3.0×109 litre−1, or both, potentially fatal complications frequently occur. Accordingly, patients need strict nutritional support to avoid re-feeding syndrome until surgery. During the course of anaesthesia, careless loading of glucose or catecholamine may lead to disturbance of electrolytes or fatal arrhythmia. Intensive care and early feeding as soon as possible after surgery are important to prevent surgical site infection. Although not many perioperative cases of AN have been reported, clinicians must be aware of the danger and the causes of mortality in critical cases. Thus, the decision to undertake surgery must be taken carefully and close perioperative coordination among physicians, surgeons, psychiatrists, anaesthesiologists, and intensivists is essential.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
Disseminated cutaneous nocardiosis with ocular involvement Nishizawa, A.; Hirose, M.; Nagata, Y. ...
Journal of the European Academy of Dermatology and Venereology,
November 2017, 2017-Nov, 2017-11-00, Volume:
31, Issue:
11
Journal Article
Peer reviewed
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