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  • Inflammation and Immunity i... Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension
    Rabinovitch, Marlene; Guignabert, Christophe; Humbert, Marc ... Circulation research, 2014-June-20, 2014-Jun-20, 2014-06-20, 20140620, Volume: 115, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    This review summarizes an expanding body of knowledge indicating that failure to resolve inflammation and altered immune processes underlie the development of pulmonary arterial hypertension. The ...
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  • Endothelial cell dysfunctio... Endothelial cell dysfunction: a major player in SARS-CoV-2 infection (COVID-19)?
    Huertas, Alice; Montani, David; Savale, Laurent ... The European respiratory journal, 07/2020, Volume: 56, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Coronavirus disease 2019 (COVID-19) represents a public health crisis of pandemic proportions. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the symptoms most commonly ...
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  • The molecular targets of ap... The molecular targets of approved treatments for pulmonary arterial hypertension
    Humbert, Marc; Ghofrani, Hossein-Ardeschir Thorax, 01/2016, Volume: 71, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Until recently, three classes of medical therapy were available for the treatment of pulmonary arterial hypertension (PAH)--prostanoids, endothelin receptor antagonists and phosphodiesterase type 5 ...
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  • Asthma and COVID-19: an update Asthma and COVID-19: an update
    Adir, Yochai; Saliba, Walid; Beurnier, Antoine ... European respiratory review, 12/2021, Volume: 30, Issue: 162
    Journal Article
    Peer reviewed
    Open access

    As the world faces the coronavirus disease 2019 (COVID-19) pandemic due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, concerns have been raised that asthma patients could ...
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  • Treatable traits: toward pr... Treatable traits: toward precision medicine of chronic airway diseases
    Agusti, Alvar; Bel, Elisabeth; Thomas, Mike ... The European respiratory journal, 02/2016, Volume: 47, Issue: 2
    Journal Article
    Peer reviewed
    Open access

    Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent chronic airway diseases that have a high personal and social impact. They likely represent a continuum of different diseases ...
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  • Management of Pulmonary Art... Management of Pulmonary Arterial Hypertension
    McLaughlin, Vallerie V., MD; Shah, Sanjiv J., MD; Souza, Rogerio, MD ... Journal of the American College of Cardiology, 05/2015, Volume: 65, Issue: 18
    Journal Article
    Peer reviewed
    Open access

    Abstract Pulmonary hypertension (PH) is common and may result from a number of disorders, including left heart disease, lung disease, and chronic thromboembolic disease. Pulmonary arterial ...
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  • Pathology and pathobiology ... Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives
    Humbert, Marc; Guignabert, Christophe; Bonnet, Sébastien ... The European respiratory journal, 01/2019, Volume: 53, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Clinical and translational research has played a major role in advancing our understanding of pulmonary hypertension (PH), including pulmonary arterial hypertension and other forms of PH with severe ...
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  • 2015 ESC/ERS Guidelines for... 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
    Galie, Nazzareno; Humbert, Marc; Vachiery, Jean-Luc ... The European respiratory journal, 10/2015, Volume: 46, Issue: 4
    Journal Article, Web Resource
    Peer reviewed
    Open access

    Guidelines summarize and evaluate all available evidence on a particular issue at the time of the writing process, with the aim of assisting health professionals in selecting the best management ...
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