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  • Competitive Interactions Be... Competitive Interactions Between Cells: Death, Growth, and Geography
    Johnston, Laura A Science (American Association for the Advancement of Science), 06/2009, Volume: 324, Issue: 5935
    Journal Article
    Peer reviewed
    Open access

    Competitive interactions between cells are the basis of many homeostatic processes in biology. Some of the best-described cases of competition between cells occur in DROSOPHILA: cell competition, ...
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2.
  • Spatially Restricted Regula... Spatially Restricted Regulation of Spätzle/Toll Signaling during Cell Competition
    Alpar, Lale; Bergantiños, Cora; Johnston, Laura A. Developmental cell, 09/2018, Volume: 46, Issue: 6
    Journal Article
    Peer reviewed
    Open access

    Cell competition employs comparisons of fitness to selectively eliminate cells sensed as less healthy. In Drosophila, apoptotic elimination of the weaker “loser” cells from growing wing discs is ...
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  • Mosaic Analysis in Drosophila Mosaic Analysis in Drosophila
    Germani, Federico; Bergantinos, Cora; Johnston, Laura A Genetics (Austin), 02/2018, Volume: 208, Issue: 2
    Journal Article
    Peer reviewed
    Open access

    Since the founding of genetics by Thomas Hunt Morgan and his colleagues over 100 years ago, the experimental induction of mosaicism has featured prominently in its recognition as an unsurpassed ...
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  • Transgender and Intersex At... Transgender and Intersex Athletes in Single-sex Sports
    Johnston, Laura Journal of law and medicine, 12/2020, Volume: 28, Issue: 1
    Journal Article
    Peer reviewed

    Transgender and intersex athlete inclusion and exclusion from single-sex sports is an area of ongoing conversation and change. This article discusses the separation of male and female athletes, ...
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5.
  • Evidence for a Growth-Stabi... Evidence for a Growth-Stabilizing Regulatory Feedback Mechanism between Myc and Yorkie, the Drosophila Homolog of Yap
    Neto-Silva, Ricardo M.; de Beco, Simon; Johnston, Laura A. Developmental cell, 10/2010, Volume: 19, Issue: 4
    Journal Article
    Peer reviewed
    Open access

    An understanding of how animal size is controlled requires knowledge of how positive and negative growth regulatory signals are balanced and integrated within cells. Here we demonstrate that the ...
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6.
  • Supercompetitor Status of D... Supercompetitor Status of Drosophila Myc Cells Requires p53 as a Fitness Sensor to Reprogram Metabolism and Promote Viability
    de la Cova, Claire; Senoo-Matsuda, Nanami; Ziosi, Marcello ... Cell metabolism, 03/2014, Volume: 19, Issue: 3
    Journal Article
    Peer reviewed
    Open access

    In growing tissues, cell fitness disparities can provoke interactions that promote stronger cells at the expense of the weaker in a process called cell competition. The mechanistic definition of cell ...
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  • The immunology of food allergy The immunology of food allergy
    Johnston, Laura K; Chien, Karen B; Bryce, Paul J The Journal of immunology (1950), 2014-Mar-15, 2014-03-15, 20140315, Volume: 192, Issue: 6
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    Open access

    Food allergies represent an increasingly prevalent human health problem, and therapeutic options remain limited, with avoidance being mainstay, despite its adverse effects on quality of life. A ...
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  • Temporal Regulation of Meta... Temporal Regulation of Metamorphic Processes in Drosophila by the let-7 and miR-125 Heterochronic MicroRNAs
    Caygill, Elizabeth E.; Johnston, Laura A. Current biology, 07/2008, Volume: 18, Issue: 13
    Journal Article
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    Open access

    The let-7 and lin-4 microRNAs belong to a class of temporally expressed, noncoding regulatory RNAs that function as heterochronic switch genes in the nematode C. elegans. Heterochronic genes control ...
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  • Pulmonary macrophage subpop... Pulmonary macrophage subpopulations in the induction and resolution of acute lung injury
    Johnston, Laura K; Rims, Cliff R; Gill, Sean E ... American journal of respiratory cell and molecular biology 47, Issue: 4
    Journal Article
    Peer reviewed
    Open access

    Macrophages are key orchestrators of the inflammatory and repair responses in the lung, and the diversity of their function is indicated by their polarized states and distinct subpopulations and ...
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  • IL-33 Precedes IL-5 in Regu... IL-33 Precedes IL-5 in Regulating Eosinophil Commitment and Is Required for Eosinophil Homeostasis
    Johnston, Laura K; Hsu, Chia-Lin; Krier-Burris, Rebecca A ... The Journal of immunology (1950), 11/2016, Volume: 197, Issue: 9
    Journal Article
    Peer reviewed
    Open access

    Eosinophils are important in the pathogenesis of many diseases, including asthma, eosinophilic esophagitis, and eczema. Whereas IL-5 is crucial for supporting mature eosinophils (EoMs), the signals ...
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