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  • Synthetic Cells Synthesize ... Synthetic Cells Synthesize Therapeutic Proteins inside Tumors
    Krinsky, Nitzan; Kaduri, Maya; Zinger, Assaf ... Advanced healthcare materials, 05/2018, Volume: 7, Issue: 9
    Journal Article
    Peer reviewed
    Open access

    Synthetic cells, artificial cell‐like particles, capable of autonomously synthesizing RNA and proteins based on a DNA template, are emerging platforms for studying cellular functions and for ...
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  • A Simple and Rapid Method f... A Simple and Rapid Method for Preparing a Cell-Free Bacterial Lysate for Protein Synthesis
    Krinsky, Nitzan; Kaduri, Maya; Shainsky-Roitman, Janna ... PloS one, 10/2016, Volume: 11, Issue: 10
    Journal Article
    Peer reviewed
    Open access

    Cell-free protein synthesis (CFPS) systems are important laboratory tools that are used for various synthetic biology applications. Here, we present a simple and inexpensive laboratory-scale method ...
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  • Sex‐Based Differences in th... Sex‐Based Differences in the Biodistribution of Nanoparticles and Their Effect on Hormonal, Immune, and Metabolic Function
    Poley, Maria; Chen, Gal; Sharf-Pauker, Noga ... Advanced NanoBiomed Research (Online), December 2022, 2022-12-00, 2022-12-01, Volume: 2, Issue: 12
    Journal Article
    Peer reviewed
    Open access

    Males and females respond differently to medications due to physiologic, metabolic, and genetic factors. At times, sex‐related differences cannot be mitigated by dose adjustment to body mass, and are ...
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  • Biocompatibility, biodegrad... Biocompatibility, biodegradation and excretion of polylactic acid (PLA) in medical implants and theranostic systems
    da Silva, Dana; Kaduri, Maya; Poley, Maria ... Chemical engineering journal (Lausanne, Switzerland : 1996), 05/2018, Volume: 340
    Journal Article
    Peer reviewed
    Open access

    •Polylactic acid (PLA) is a biocompatible polymer that is used widely for biomedical applications.•PLA biodegrades into lactic acid (LA) or to carbon dioxide and water.•PLA degradation products are ...
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  • Implanted synthetic cells t... Implanted synthetic cells trigger tissue angiogenesis through de novo production of recombinant growth factors
    Chen, Gal; Levin, Rotem; Landau, Shira ... Proceedings of the National Academy of Sciences - PNAS, 09/2022, Volume: 119, Issue: 38
    Journal Article
    Peer reviewed
    Open access

    Progress in bottom-up synthetic biology has stimulated the development of synthetic cells (SCs), autonomous protein-manufacturing particles, as dynamic biomimetics for replacing diseased natural ...
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  • Nanoparticles Accumulate in... Nanoparticles Accumulate in the Female Reproductive System during Ovulation Affecting Cancer Treatment and Fertility
    Poley, Maria; Mora-Raimundo, Patricia; Shammai, Yael ... ACS nano, 04/2022, Volume: 16, Issue: 4
    Journal Article
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    Open access

    Throughout the female menstrual cycle, physiological changes occur that affect the biodistribution of nanoparticles within the reproductive system. We demonstrate a 2-fold increase in nanoparticle ...
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  • Brain‐Targeted Liposomes Lo... Brain‐Targeted Liposomes Loaded with Monoclonal Antibodies Reduce Alpha‐Synuclein Aggregation and Improve Behavioral Symptoms in Parkinson's Disease
    Sela, Mor; Poley, Maria; Mora‐Raimundo, Patricia ... Advanced materials (Weinheim), 12/2023, Volume: 35, Issue: 51
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    Open access

    Monoclonal antibodies (mAbs) hold promise in treating Parkinson's disease (PD), although poor delivery to the brain hinders their therapeutic application. In the current study, it is demonstrated ...
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  • Preparing Protein Producing... Preparing Protein Producing Synthetic Cells using Cell Free Bacterial Extracts, Liposomes and Emulsion Transfer
    Adir, Omer; Sharf-Pauker, Noga; Chen, Gal ... Journal of visualized experiments, 04/2020, Volume: 158, Issue: 158
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    Peer reviewed
    Open access

    The bottom-up assembly approach for construction of synthetic cells is an effective tool for isolating and investigating cellular processes in a cell mimicking environment. Furthermore, the ...
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  • Brain‐Targeted Liposomes Lo... Brain‐Targeted Liposomes Loaded with Monoclonal Antibodies Reduce Alpha‐Synuclein Aggregation and Improve Behavioral Symptoms in Parkinson's Disease (Adv. Mater. 51/2023)
    Sela, Mor; Poley, Maria; Mora‐Raimundo, Patricia ... Advanced materials (Weinheim), 12/2023, Volume: 35, Issue: 51
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    Open access

    Brain‐Targeted Liposomes In article number 2304654, Avi Schroeder and co‐workers describe a targeted nanotechnology drug delivery system for treating Parkinson's disease. Brain‐targeted ...
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