Using an electron-positron collision data sample of 2.93 fb−1 collected at a center-of-mass energy of s=3.773 GeV with the BESIII detector, we present the first search for the radiative leptonic ...decay D+→γe+νe. The analysis is performed with a double-tag method. We do not observe a significant D+→γe+νe signal, and obtain an upper limit on the branching fraction of D+→γe+νe decay with the energy of radiative photon larger than 10 MeV of 3.0×10−5 at the 90% confidence level.
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CMK, CTK, FMFMET, IJS, NUK, PNG, UM
Co3O4 has shown acceptable electrochemical properties as the anode material of Li secondary batteries. In detail, its capacity reached about 700 mAh/g, twice as high as graphite, and 93.4% of initial ...capacity was retained after 100 cycles. EIS (electrochemical impedance spectroscopy) analyses revealed that after the 1st cycle, the insertion or extraction of Li ions in Co3O4 can occur homogeneously and reversibly (randless-like behavior, homogeneous mixture: Co + Li2O (in the state of Li insertion), Co3O4 (in the state of Li extraction)). In fact, the coulombic efficiency of Co3O4 was almost 100% except for the 1st cycle. According to P. Poizot's research on several kinds of transition metal oxides, such as Co3O4, CoO, NiO, etc., a small Li2O particle size and catalytic activity of the transition metal are expected to decrease the binding energy of Li2O tremendously. As a result, Li2O should be easy to decompose, and transition metal oxides should be able to charge or discharge reversibly by formation or decomposition of Li2O. However, this assumption has never been confirmed by experimental results. In our results, the CV (cyclic voltammogram) of a Li2O-Co mixture shows much larger oxidation and reduction peaks than that of Li2O. Based on XRD analyses, oxidation and reduction in the CV of Li2O correspond, respectively, to the decomposition and formation of Li2O. So, it can be asserted that Co addition to Li2O facilitates decomposition and formation processes in Li2O and that the catalytic effect of the transition metal must be one of the main causes that make Li2O form or decompose repeatedly.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
A 36-year-old male patient presented with a decrease in vision after undergoing scleral suturing for a left eye injury caused by an iron hook, combined with intravitreal injection of cefuroxime. ...Ocular examination revealed extensive gray-white edematous areas in the macular region, along with focal serous shallow retinal detachment in the posterior pole. Following admission, comprehensive ophthalmic examinations were conducted, leading to the diagnosis of toxic retinal damage in the left eye. Treatment with oral corticosteroids and interventions to improve microcirculation were initiated, resulting in improved visual acuity. At the six-month follow-up, the patient's visual acuity had recovered to 0.5.
Flexible photodetector shows great potential applications in intelligent wearable devices, health monitoring, and biological sensing. In this work, single crystal β-tellurium nanowires were grown on ...flexible muscovite by molecular beam epitaxy, constructing high-density ordered nanomesh structure. The prepared photodetectors based on tellurium nanomesh exhibit excellent mechanical flexibility, fast response in a broad range from ultraviolet to near-infrared, and good photosensitivity. We found that the flexible photodetectors with Shottky contact drastically suppressed dark current, while the response speed was lowered in comparison to the devices with ohmic contact, as holes would take a long time to tunnel through the Shottky barrier between metal and p-type Te. Moreover, the photoresponse of flexible Shottky photodetectors can be modulated by piezoelectricity of tellurium, and pronounced photocurrent increase after bending many times. Under external stress, polarization charges could tune Shottky barrier height of the metal/tellurium, resulting in variation of photocurrent. This research not only explores the broadband photoresponse and piezoelectric effect of tellurium nanomesh, but also promotes the integration and development of broadband flexible optoelectronic devices.
Aberrant activation of the JAK3-STAT signaling pathway is a characteristic feature of many hematological malignancies. In particular, hyperactivity of this cascade has been observed in natural ...killer/T-cell lymphoma (NKTL) cases. Although the first-in-class JAK3 inhibitor tofacitinib blocks JAK3 activity in NKTL both in vitro and in vivo, its clinical utilization in cancer therapy has been limited by the pan-JAK inhibition activity. To improve the therapeutic efficacy of JAK3 inhibition in NKTL, we have developed a highly selective and durable JAK3 inhibitor PRN371 that potently inhibits JAK3 activity over the other JAK family members JAK1, JAK2, and TYK2. PRN371 effectively suppresses NKTL cell proliferation and induces apoptosis through abrogation of the JAK3-STAT signaling. Moreover, the activity of PRN371 has a more durable inhibition on JAK3 compared to tofacitinib in vitro, leading to significant tumor growth inhibition in a NKTL xenograft model harboring JAK3 activating mutation. These findings provide a novel therapeutic approach for the treatment of NKTL.
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EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
A proteomic approach combining two-dimensional polyacrylamide gel electrophoresis and tandem mass spectrometry was used to compare hemolymph expression profiles of a beta-cypermethrin-resistant ...Blattella germanica L. strain and a beta-cypermethrin-susceptible strain. Twenty-eight hemolymph proteins were differentially expressed in the resistant cockroach strain; 19 proteins were upregulated and 9 proteins were downregulated compared with the susceptible strain. Protein identification indicated that expression of putative cuticular protein, nitric oxide synthase, triosephosphate isomerase, alpha-amylase, ABC transporter, and Per a 3 allergen was elevated, and expression of arginine kinase and glycosidase was reduced. The differential expression of these proteins reflects the overall change in cellular structure and metabolism related to the resistance of pyrethroid insecticides.
In order to prevent polysulfide dissolution into liquid electrolytes and to promote the Li/S redox reaction (16Li + S8 H < -- > Li2Sn < -- > Li2S), nanosized Mg0.6Ni0.4O, which has the catalytic ...effect of chemical bond dissociating and is expected to have an adsorbing effect due to the effect of retaining liquid electrolyte of MgO in a Li/iron sulfide secondary battery, was prepared by the sol-gel method as an electrochemically inactive additive for an elemental sulfur cathode for Li/S rechargeable batteries. The Li/S battery using an elemental sulfur cathode with a nanosized Mg0.6Ni0.4O added showed the improvement of not only the discharge capacity but also cycle durability (maximum discharge capacity: 1185 mAh/g sulfur, C50/C1 = 85%). The rate capability of the sulfur cathode was also increased with the addition of the nanosized Mg0.6Ni04O. From the results, it is confirmed that the nanosized Mg0.6Ni0.4O had the polysulfide adsorbing effect and the catalytic effect of promoting Li/S redox reaction. Furthermore, it is found that the nanosized Mg0.6Ni0.4O also increased the porosity of the sulfur cathode.
The B20 chiral magnets with broken inversion symmetry and C4 rotation symmetry have attracted much attention. The broken inversion symmetry leads to the Dzyaloshinskii-Moriya that gives rise to the ...helical and Skyrmion states. We report the unusual magnetoresistance (MR) of B20 chiral magnet Fe0.85Co0.15Si that directly reveals the broken C4 rotation symmetry and shows the anisotropic scattering by Skyrmions with respect to the current directions. The intimacy between unusual MR and broken symmetry is well confirmed by theoretically studying an effective Hamiltonian with spin-orbit coupling. The unusual MR serves as a transport signature for the Skyrmion phase.
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