Estrogen and its receptors are essential for sexual development and reproduction. Oestrogen receptor alpha (ERα) is a nuclear receptor activated by the hormone oestrogen. In male, ERα is encoded by ...the gene ESR1 (oestrogen receptor1) responsible for better fertility. ESR1 is involved in the reabsorption of luminal fluid during the transit of spermatozoa from the testis to the head of the epididymis which is important for their survival and maturation during epididymal storage. The absence of ESR1 leads to reduced epididymal sperm content, reduced sperm motility and fertilizing ability. The present study was undertaken to investigate the expression and presence of ESR1 gene in fertile and low‐fertile male goat breeds. We identified ESR1 gene through various molecular tools. Genotyping was carried out by high resonance melting analysis using Roche Light Cycler 480(LC‐480) system and found three different genotypes. Genotypic frequency‐AA (blue‐0.67), BB(Red‐0.2), AB(Green‐0.08) with allele frequency A(0.71 and B (0.29). The predominance of this gene in head of epididymis in fertile bucks was confirmed by SDS‐PAGE, Western blotting and immunohistochemistry. From the results, we corroborated that the present study provides a useful and effective way to predict male fertility in goat breeds, which in turn increases the percentage of fertility in flock leading to more number of offspring in a kidding season.
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BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SAZU, SBCE, SBMB, UL, UM, UPUK
Temperature-dependent 57Fe Mössbauer spectroscopy (5-723 K) and neutron diffraction (2-290 K) measurements are carried out on polycrystalline magnetoelectric GaFeO3. From the neutron diffraction ...data, evidence for the magnetostriction and increased disorder at Fe sites close to the ferrimagnetic Curie transition temperature (TC) is observed. From the Mössbauer data, it is observed that the Lamb-Mössbauer factor as a function of temperature f(T), which is related to the integral over the first Brillouin zone of the phonon spectrum, shows a unequivocal variation at the TC. The observations are discussed in terms of spin-phonon coupling. The observed average hyperfine fields from 57Fe Mössbauer spectra match with the bulk magnetization data. A critical exponent (β) of 0.38 ± 0.02 and a Debye temperature (θD) of ∼350 K is estimated from the 57Fe Mössbauer data.
In this paper, we propose a method for the analysis and classification of electroencephalogram (EEG) signals using EEG rhythms. The EEG rhythms capture the nonlinear complex dynamic behavior of the ...brain system and the nonstationary nature of the EEG signals. This method analyzes common frequency components in multichannel EEG recordings, using the filter bank signal processing. The mean frequency (MF) and RMS bandwidth of the signal are estimated by applying Fourier-transform-based filter bank processing on the EEG rhythms, which we refer intrinsic band functions, inherently present in the EEG signals. The MF and RMS bandwidth estimates, for the different classes (e.g., ictal and seizure-free, open eyes and closed eyes, inter-ictal and ictal, healthy volunteers and epileptic patients, inter-ictal epileptogenic and opposite to epileptogenic zone) of EEG recordings, are statistically different and hence used to distinguish and classify the two classes of signals using a least-squares support vector machine classifier. Experimental results, with 100 % classification accuracy, on a real-world EEG signals database analysis illustrate the effectiveness of the proposed method for EEG signal classification.
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EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
Background: The ongoing coronavirus disease 2019 (COVID-19) pandemic has placed an unprecedented strain on Indian healthcare systems, with rapidly increasing demand for life-saving equipment and ...intensive care unit beds. The present study presents an analysis of average length of stay (LOS) as per different demographic and clinical factors in a dedicated COVID hospital. As the pandemic escalates, average LOS in COVID hospital will form the basis of determining the optimum requirement for healthcare resources (beds, staff, and equipment), which is a key priority for bolstering a strong public health response against COVID-19. Materials and Methods: Using the medical records at a dedicated COVID-19 hospital, the demographic details and select clinical characteristics of 342 admitted patients (from July 13, 2020, to August 30, 2020) were abstracted. Hospital LOS, calculated from the actual admission and discharge dates, was compared within the categories of demographic and clinical characteristics using Student's test and analysis of variance. SPSS version 20 was used for descriptive as well as inferential statistics. Results: The mean LOS was 9.93 ± 4.45 days with a range of 3–37 days. LOS increased with increasing age, with maximum being for >61 years (12.69 ± 7.14) and minimum for the younger age category of <40 years (8.88 ± 1.95) ( P = 0.001). As COVID-19 severity increased, LOS increased, with longest being for severe patients (25.59 ± 7.30) and shortest being for Mild patients (8.74 ± 1.80) ( P = 0.001). LOS was also longer for patients having multiple comorbidities (13.00 ± 7.96) and shortest for those with no comorbidities (9.33 ± 2.96) ( P = 0.001). Conclusion: LOS is significantly affected by age, severity, and comorbidities. The actual duration and factors influencing LOS are crucial for health administrators and policymakers to better allocate the already scarce health resources.
FeMnO3, prepared by mechano-synthesis method using high energy planetary ball mill, crystallizes in bixbyite type cubic structure in space group Ia3. Magnetic measurements show that the compound is ...ferrimagnetic at room temperature and on cooling undergoes antiferromagnetic ordering around, To~ 36K. Magnetization measurements exhibit strong magnetic anisotropy in this system. Change in the magnetic entropy, also known as the magnetocaloric effect, has been observed in FeMnO3 on subjecting the sample to a changing magnetic field. We found maximum change of magnetic entropy ~1.5J/kgK, for a field change of 90kOe at T~2To with relative cooling power of 50J/kg.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
Layered oxide BiPbSr
2
MnO
6
(BPSMO) is investigated from structural, magnetic and magnetodielectric perspective. Room temperature Rietveld refinement of neutron powder diffraction pattern shows that ...the compound crystallizes in orthorhombic ‘
Amaa
’ structure. Along with an antiferromagnetic ordering (T
N
) at 190 K, a weak ferromagnetic component is substantiated from magnetization isotherm measured at 175 K as well as temperature dependent neutron powder diffraction. Magnetic reflections were indexed in the nuclear lattice with propagation vector
k
= (0, 0, 0). Rietveld refinement of powder pattern at 2.8 K demonstrates that magnetic moments are almost normal to the
a–b
plane in an antiferromagnetic arrangement, but are canted slightly towards
a–b
plane. The Jahn–Teller distortion shows a substantial increase in the ordered state with decrease in temperature while the variation is trifling above the ordering temperature. The dielectric measurement shows a contrasting nature of the dielectric data for temperatures below and above T
N
, thus hinting a plausible magnetodielectric (MD) coupling. A confirmation to this coupling is seen in the temperature and field dependent magnetodielectric (MD) results. Substantial MD effect of ~ − 2% is observed at 175 K, near to the vicinity of magnetic transition.
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EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OBVAL, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
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