Abstract Recent substantial evidence implicating commensal bacteria in human diseases has given rise to a new domain in biomedical research: microbiome medicine. This emerging field aims to ...understand and leverage the human microbiota and derivative molecules for disease prevention and treatment. Despite the complex and hierarchical organization of this ecosystem, most research over the years has relied on 16S amplicon sequencing, a legacy of bacterial phylogeny and taxonomy. Although advanced sequencing technologies have enabled cost-effective analysis of entire microbiota, translating the relatively short nucleotide information into the functional and taxonomic organization of the microbiome has posed challenges until recently. In the last decade, genome-resolved metagenomics, which aims to reconstruct microbial genomes directly from whole-metagenome sequencing data, has made significant strides and continues to unveil the mysteries of various human-associated microbial communities. There has been a rapid increase in the volume of whole metagenome sequencing data and in the compilation of novel metagenome-assembled genomes and protein sequences in public depositories. This review provides an overview of the capabilities and methods of genome-resolved metagenomics for studying the human microbiome, with a focus on investigating the prokaryotic microbiota of the human gut. Just as decoding the human genome and its variations marked the beginning of the genomic medicine era, unraveling the genomes of commensal microbes and their sequence variations is ushering us into the era of microbiome medicine. Genome-resolved metagenomics stands as a pivotal tool in this transition and can accelerate our journey toward achieving these scientific and medical milestones.
Abstract
This paper introduces a real-time Driver Monitoring System (DMS) designed to monitor driver behavior while driving, employing facial landmark estimation-based behavior recognition. The ...system utilizes an infrared (IR) camera to capture and analyze video data. Through facial landmark estimation, crucial information about the driver’s head posture and eye area is extracted from the detected facial region, obtained via face detection. The proposed method consists of two distinct modules, each focused on recognizing specific behaviors. The first module employs head pose analysis to detect instances of inattention. By monitoring the driver’s head movements along the horizontal and vertical axes, this module assesses the driver’s attention level. The second module implements an eye-closure recognition filter to identify instances of drowsiness. Depending on the continuity of eye closures, the system categorizes them as either occasional drowsiness or sustained drowsiness. The advantages of the proposed method lie in its efficiency and real-time capabilities, as it solely relies on IR camera video for computation and analysis. To assess its performance, the system underwent evaluation using IR-Datasets, demonstrating its effectiveness in monitoring and recognizing driver behavior accurately. The presented real-time Driver Monitoring System with facial landmark-based behavior recognition offers a practical and robust approach to enhance driver safety and alertness during their journeys.
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IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
Topological qubits based on Majorana Fermions have the potential to revolutionize the emerging field of quantum computing by making information processing significantly more robust to decoherence. ...Nanowires are a promising medium for hosting these kinds of qubits, though branched nanowires are needed to perform qubit manipulations. Here we report a gold-free templated growth of III–V nanowires by molecular beam epitaxy using an approach that enables patternable and highly regular branched nanowire arrays on a far greater scale than what has been reported thus far. Our approach relies on the lattice-mismatched growth of InAs on top of defect-free GaAs nanomembranes yielding laterally oriented, low-defect InAs and InGaAs nanowires whose shapes are determined by surface and strain energy minimization. By controlling nanomembrane width and growth time, we demonstrate the formation of compositionally graded nanowires with cross-sections less than 50 nm. Scaling the nanowires below 20 nm leads to the formation of homogeneous InGaAs nanowires, which exhibit phase-coherent, quasi-1D quantum transport as shown by magnetoconductance measurements. These results are an important advance toward scalable topological quantum computing.
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IJS, KILJ, NUK, PNG, UL, UM
We proposed a novel electromagnetic band-gap (EBG) cell-embedded antenna structure for reducing the interference that radiates at the antenna edge in wireless access in vehicular environment (WAVE) ...communication systems for vehicle-to-everything communications. To suppress the radiation of surface waves from the ground plane and vehicle, EBG cells were inserted between micropatch arrays. A simulation was also performed to determine the optimum EBG cell structure located above the ground plane in a conformal linear microstrip patch array antenna. The characteristics such as return loss, peak gain, and radiation patterns obtained using the fabricated EBG cell-embedded antenna were superior to those obtained without the EBG cells. A return loss of 35.14 dB, peak gain of 10.15 dBi at 80°, and improvement of 2.037 dB max at the field of view in the radiation beam patterns were obtained using the proposed WAVE antenna.
We proposed a novel electromagnetic band‐gap (EBG) cell‐embedded antenna structure for reducing the interference that radiates at the antenna edge in wireless access in vehicular environment (WAVE) ...communication systems for vehicle‐to‐everything communications. To suppress the radiation of surface waves from the ground plane and vehicle, EBG cells were inserted between micropatch arrays. A simulation was also performed to determine the optimum EBG cell structure located above the ground plane in a conformal linear microstrip patch array antenna. The characteristics such as return loss, peak gain, and radiation patterns obtained using the fabricated EBG cell‐embedded antenna were superior to those obtained without the EBG cells. A return loss of 35.14 dB, peak gain of 10.15 dBi at 80°, and improvement of 2.037 dB max at the field of view in the radiation beam patterns were obtained using the proposed WAVE antenna.
Purpose: This study aimed to identify the effects of myofascial pain syndrome on shoulder pain, range of motion, and body composition around the shoulder in middle-aged women. Methods: A total of 72 ...women participated in the randomized controlled trial. The subjects were grouped into an experimental group (n=39) and a control group (n=33). The experimental group received a resistance exercise program using an elastic band for 8 weeks, 3 days a week. The control group followed a normal daily for 8 weeks. Measurements were conducted three times; before the experimental treatment (pre-test), the 2nd and 8th weeks after treatment. Results: Regarding the general characteristics and homogeneity of the dependent variables, there were no significant differences between the two groups, except for the thickness of the left and right muscles and the left fat. After treatment, shoulder pain was significantly different between the two groups (F=18.54, p<.001) and the range of shoulder motion was significantly different (left, F=86.70, p<.001; right, F=98.66, p<.001). Furthermore, there were a significant differences in the thickness of muscles between the two groups (left, F=40.20, p<.001; right, F=29.57, p<.001); however, the thickness of fat was not significantly different. Conclusion: The resistance exercise program reduces shoulder pain and improves the range of motion of the shoulder joint and increases muscle mass on around the shoulder. It suggests to conduct a study to confirm the long-term exercise effect.
In this paper, a staggered cell-centered discontinuous Galerkin method is developed for the biharmonic problem with the Steklov boundary condition. Our approach utilizes a first-order system form of ...the biharmonic problem and can handle fairly general meshes possibly including hanging nodes, which favors adaptive mesh refinement. Optimal order error estimates in L2 norm can be proved for all the variables. Moreover, the approximation of the primal variable superconverges in L2 norm to a suitably chosen projection without requiring additional regularity. Residual type error estimators are proposed, which can guide adaptive mesh refinement to deliver optimal convergence rates even for solutions with singularity. Numerical experiments confirm that the optimal convergence rates in L2 norm can be achieved for all the variables. Moreover, all the provided residual type error estimators show the desired results. In particular, the numerical results demonstrate that the proposed scheme on a polygonal approximation of the disk works well for the classic Babuška example.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
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BFBNIB, NUK, PILJ, SAZU, UL, UM, UPUK
10.
아로마 에센셜 오일 흡입이 밤번 근무 간호사의 수면의 질에 미치는 효과 김원종(Kim, WonJong); 허명행(Hur, Myung-Haeng)
Journal of Korean Academy of Nursing,
2016, Volume:
46, Issue:
6
Journal Article
Peer reviewed
Open access
Purpose: This study was an experimental study to compare the inhalation effects of aroma essential oil on the quality of sleep (QOS) for shift nurses after working nights. Methods: The participants ...were 60 healthy adults who didn't have any disease. As an experimental treatment, the participants in the experimental group were asked to inhale essential oil for 3 minutes at a distance of approximately 10 cm from their nose and then they were asked to sleep with the aroma stone beside their head (within a 30 cm distance). QOS were measured four times on Pretest, Day 1, Day 2, and Day 3 after they slept. To measure QOS, Perceived QOS (Numeric Rating Scale), the Verran & Synder-Halpern (VSH) Sleep Scale were used, and number of awakenings (NoA) was measured by Actigraph. Results: There were no significant differences in the homogeneity tests for general characteristics and dependent variables prior to the experiments, except for VSH of subjective sleep quality. Also, there was no significant interaction between group and time. The VSH of the experimental group was higher than the control group (F=6.39, p=.002). The NoA between the experimental group and the control group was significantly different after experimental treatment 3rd day (F=13.35, p=.001). Conclusion: The findings show that the inhalation of aroma essential oil had effects to increase the quality of sleep. Therefore, the inhalation of aroma essential oil could be applied to general nursing interventions to improve the quality of sleep.