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  • Exome array analysis identi... Exome array analysis identifies CAV1/CAV2 as a susceptibility locus for intraocular pressure
    Chen, Fei; Klein, Alison P; Klein, Barbara E K ... Investigative ophthalmology & visual science, 01/2015, Volume: 56, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Intraocular pressure (IOP) is an important clinical parameter in the evaluation of ocular health. Elevated IOP is a major risk factor for primary open-angle glaucoma (POAG). The goal of this study ...
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  • Upregulation of CD38 expres... Upregulation of CD38 expression on multiple myeloma cells by all-trans retinoic acid improves the efficacy of daratumumab
    Nijhof, I S; Groen, R W J; Lokhorst, H M ... Leukemia, 10/2015, Volume: 29, Issue: 10
    Journal Article
    Peer reviewed
    Open access

    Daratumumab is an anti-CD38 monoclonal antibody with lytic activity against multiple myeloma (MM) cells, including ADCC (antibody-dependent cellular cytotoxicity) and CDC (complement-dependent ...
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  • Anti-PD-1 therapy in patien... Anti-PD-1 therapy in patients with advanced melanoma and preexisting autoimmune disorders or major toxicity with ipilimumab
    Menzies, A.M.; Johnson, D.B.; Ramanujam, S. ... Annals of oncology, February 2017, 2017-02-01, 2017-02-00, Volume: 28, Issue: 2
    Journal Article
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    Open access

    Anti-PD-1 antibodies (anti-PD-1) have clinical activity in a number of malignancies. All clinical trials have excluded patients with significant preexisting autoimmune disorders (ADs) and only one ...
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  • Redox proteomic identificat... Redox proteomic identification of HNE-bound mitochondrial proteins in cardiac tissues reveals a systemic effect on energy metabolism after doxorubicin treatment
    Zhao, Y.; Miriyala, S.; Miao, L. ... Free radical biology & medicine, 07/2014, Volume: 72
    Journal Article
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    Doxorubicin (DOX), one of the most effective anticancer drugs, is known to generate progressive cardiac damage, which is due, in part, to DOX-induced reactive oxygen species (ROS). The elevated ROS ...
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  • Role of Glucosyltransferase... Role of Glucosyltransferase B in Interactions of Candida albicans with Streptococcus mutans and with an Experimental Pellicle on Hydroxyapatite Surfaces
    GREGOIRE, S; XIAO, J; KOO, H ... Applied and Environmental Microbiology, 09/2011, Volume: 77, Issue: 18
    Journal Article
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    Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue ...
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  • Disk or Companion: Characte... Disk or Companion: Characterizing Excess Infrared Flux in Seven White Dwarf Systems with Near-infrared Spectroscopy
    Owens, Dylan; Xu, Siyi; Manjavacas, Elena ... The Astronomical journal, 07/2023, Volume: 166, Issue: 1
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    Abstract Excess infrared flux from white dwarf stars is likely to arise from a dusty debris disk or a cool companion. In this work, we present near-infrared spectroscopic observations with ...
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  • Genome-wide association ide... Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration
    Kopplin, L J; Igo, Jr, R P; Wang, Y ... Genes and immunity, 12/2010, Volume: 11, Issue: 8
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    Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly in the developed world. We conducted a genome-wide association study in a series of families enriched for AMD ...
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  • Towards a Formal Framework ... Towards a Formal Framework of Vulnerability to Climate Change
    Ionescu, Cezar; Klein, Richard J. T; Hinkel, Jochen ... Environmental modeling & assessment, 02/2009, Volume: 14, Issue: 1
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    There is confusion regarding the notion of “vulnerability” in the climate change scientific community. Recent research has identified a need for formalisation, which would support accurate ...
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  • Lymphatic anomalies during ... Lymphatic anomalies during lifetime in patients with Noonan syndrome: Retrospective cohort study
    Swarts, Jessie W.; Kleimeier, Lotte E. R.; Leenders, Erika K. S. M ... American journal of medical genetics. Part A, November 2022, Volume: 188, Issue: 11
    Journal Article
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    Noonan syndrome (NS) has been associated with an increased risk of lymphatic anomalies, with an estimated prevalence of 20%. The prevalence of lymphatic anomalies seems to differ between pathogenic ...
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  • Graphene Sensor Arrays for ... Graphene Sensor Arrays for Rapid and Accurate Detection of Pancreatic Cancer Exosomes in Patients’ Blood Plasma Samples
    Yin, Tianyi; Xu, Lizhou; Gil, Bruno ... ACS nano, 08/2023, Volume: 17, Issue: 15
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    Biosensors based on graphene field effect transistors (GFETs) have the potential to enable the development of point-of-care diagnostic tools for early stage disease detection. However, issues with ...
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