In voice research and clinical assessment, many objective parameters are in use. However, there is no commonly used set of parameters that reflect certain voice disorders, such as functional ...dysphonia (FD); i.e. disorders with no visible anatomical changes. Hence, 358 high-speed videoendoscopy (HSV) recordings (159 normal females (N
), 101 FD females (FD
), 66 normal males (N
), 32 FD males (FD
)) were analyzed. We investigated 91 quantitative HSV parameters towards their significance. First, 25 highly correlated parameters were discarded. Second, further 54 parameters were discarded by using a LogitBoost decision stumps approach. This yielded a subset of 12 parameters sufficient to reflect functional dysphonia. These parameters separated groups N
vs. FD
and N
vs. FD
with fair accuracy of 0.745 or 0.768, respectively. Parameters solely computed from the changing glottal area waveform (1D-function called GAW) between the vocal folds were less important than parameters describing the oscillation characteristics along the vocal folds (2D-function called Phonovibrogram). Regularity of GAW phases and peak shape, harmonic structure and Phonovibrogram-based vocal fold open and closing angles were mainly important. This study showed the high degree of redundancy of HSV-voice-parameters but also affirms the need of multidimensional based assessment of clinical data.
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IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
Echternach et al discuss their study on impulse dispersion of aerosols during singing and speaking as a potential COVID-19 transmission pathway. Group singing events have been associated with several ...outbreaks of infection during the coronavirus disease (COVID-19) pandemic. This link supports the possibility that aerosols are partly responsible for person-to-person infection. The study aims to analyze the impulse dispersion dynamics of aerosols in professional singers concerning the differences between singing a text, singing a vowel, or speaking at different levels of loudness.
Group musical activities using wind instruments have been restricted during the CoVID19 pandemic due to suspected higher risk of virus transmission. It was presumed that the aerosols exhaled through ...the tubes while playing would be ejected over larger distances and spread into the room due to jet stream effects. In particular, the soprano recorder is widely used as an instrument in school classes, for beginners of all age groups in their musical education, in the context of leisure activities and in professional concert performances. Understanding the aerosol impulse dispersion characteristics of playing the soprano recorder could assist with the establishment of concepts for safe music-making. Five adult professionally trained soprano recorder players (4 female, 1 male) played four bars of the main theme of L. van Beethoven's "Ode to Joy" in low and in high octaves, as well as with 3 different potential protection devices in the high octave. For comparison they spoke the corresponding text by F. Schiller. Before each task, they inhaled .5 L of vapor from an e-cigarette filled with base liquid. The vapor cloud escaping during speaking or playing was recorded by cameras and its spread was measured as a function of time in the three spatial dimensions. The potential safety devices were rated for practicability with a questionnaire, and their influence on the sound was compared, generating a long-term average spectrum from the audio data. When playing in the high octave, at the end of the task the clouds showed a median distance of 1.06 m to the front and .57 m diameter laterally (maxima: x: 1.35 m and y: .97 m). It was found that the clouds' expansion values in playing the recorder with and without safety measures are mostly lower when compared to the ordinary, raised speaking voice of the same subjects. The safety devices which covered the instrument did not show clear advantages and were rated as unpractical by the subjects. The most effective reduction of the cloud was reached when playing into a suction funnel. The aerosol dispersion characteristics of soprano recorders seem comparable to clarinets. The tested safety devices which covered holes of the instrument did not show clear benefits.
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DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
For the clinical analysis of underlying mechanisms of voice disorders, we developed a numerical aeroacoustic larynx model, called
, that mimics commonly observed functional laryngeal disorders as ...glottal insufficiency and vibrational left-right asymmetries. The model is a combination of the Finite Volume (FV) CFD solver Star-CCM+ and the Finite Element (FE) aeroacoustic solver CFS++.
models turbulence using Large Eddy Simulations (LES) and the acoustic wave propagation with the perturbed convective wave equation (PCWE). Its geometry corresponds to a simplified larynx and a vocal tract model representing the vowel /a/. The oscillations of the vocal folds are externally driven. In total, 10 configurations with different degrees of functional-based disorders were simulated and analyzed. The energy transfer between the glottal airflow and the vocal folds decreases with an increasing glottal insufficiency and potentially reflects the higher effort during speech for patients being concerned. This loss of energy transfer may also have an essential influence on the quality of the sound signal as expressed by decreasing sound pressure level (SPL), Cepstral Peak Prominence (CPP), and Vocal Efficiency (VE). Asymmetry in the vocal fold oscillations also reduces the quality of the sound signal. However,
confirmed previous clinical and experimental observations that a high level of glottal insufficiency worsens the acoustic signal quality more than oscillatory left-right asymmetry. Both symptoms in combination will further reduce the quality of the sound signal. In summary,
allows for detailed analysis of the origins of disordered voice production and hence fosters the further understanding of laryngeal physiology, including occurring dependencies. A current walltime of 10 h/cycle is, with a prospective increase in computing power, auspicious for a future clinical use of
.
Abstract Within the human larynx, the ventricular folds serve primarily as a protecting valve during swallowing. They are located directly above the sound-generating vocal folds. During normal ...phonation, the ventricular folds are passive structures that are not excited to periodical oscillations. However, the impact of the ventricular folds on the phonation process has not yet been finally clarified. An experimental synthetic human larynx model was used to investigate the effect of the ventricular folds on the phonation process. The model includes self-oscillating vocal fold models and allows the comparison of the pressure distribution at multiple locations in the larynx for configurations with and without ventricular folds. The results indicate that the ventricular folds increase the efficiency of the phonation process by reducing the phonation threshold level of the pressure below the vocal folds. Two effects caused by the ventricular folds could be identified as reasons: (1) a decrease in the mean pressure level in the region between vocal and ventricular folds (ventricles) and (2) an increase in the glottal flow resistance. The reason for the first effect is a reduction of the pressure level in the ventricles due to the jet entrainment and the low static pressure in the glottal jet. The second effect results from an increase in the glottal flow resistance that enhances the aerodynamic energy transfer into the vocal folds. This effect reduces the onset threshold of the pressure difference across the glottis.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK, ZRSKP
Musical activities, especially singing and playing wind instruments, have been singled out as potentially high-risk activities for the transmission of SARS CoV-2, due to a higher rate of aerosol ...production and emission. Playing wind instruments can produce condensation, droplets of saliva, and aerosol particles, which hover and spread in the environmental air's convectional flows and which can be potentially infectious. The aim of this study is to investigate the primary impulse dispersion of aerosols that takes place during the playing of different wind instruments as compared to breathing and to speaking. Nine professional musicians (3 trumpeters, 3 flautists and 3 clarinetists) from the Bavarian Symphony Orchestra performed the main theme from the 4th movement of Ludwig van Beethoven's 9th symphony in different pitches and loudness. The inhaled air volume was marked with small aerosol particles produced using a commercial e-cigarette. The expelled aerosol cloud was recorded by cameras from different perspectives. Afterwards, the dimensions and dynamics of the aerosol cloud were measured by segmenting the video footage at every time point. Overall, the flutes produced the largest dispersion at the end of the task, reaching maximum forward distances of 1.88 m. An expulsion of aerosol was observed in different directions: upwards and downwards at the mouthpiece, at the end of the instrument, and along the flute at the key plane. In comparison, the maximum impulse dispersions generated by the trumpets and clarinets were lower in frontal and lateral direction (1.2 m and 1.0 m towards the front, respectively). Also, the expulsion to the sides was lower.
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DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Laryngeal videoendoscopy is one of the main tools in clinical examinations for voice disorders and voice research. Using high-speed videoendoscopy, it is possible to fully capture the vocal fold ...oscillations, however, processing the recordings typically involves a time-consuming segmentation of the glottal area by trained experts. Even though automatic methods have been proposed and the task is particularly suited for deep learning methods, there are no public datasets and benchmarks available to compare methods and to allow training of generalizing deep learning models. In an international collaboration of researchers from seven institutions from the EU and USA, we have created BAGLS, a large, multihospital dataset of 59,250 high-speed videoendoscopy frames with individually annotated segmentation masks. The frames are based on 640 recordings of healthy and disordered subjects that were recorded with varying technical equipment by numerous clinicians. The BAGLS dataset will allow an objective comparison of glottis segmentation methods and will enable interested researchers to train their own models and compare their methods.
Numerical modeling of the human phonatory process has become more and more in focus during the last two decades. The increase in computational power and the use of high-performance computation (HPC) ...yielded more complex models being closer to the actual fluid-structure-acoustic interaction (FSAI) within the human phonatory process. However, several different simulation approaches with varying mathematical complexity and focus on certain parts of the phonatory process exist. Currently, models are suggested based on ordinary differential equations (reduced order models) but also on partial differential equations based on continuum mechanics as e.g. the Navier–Stokes equations for the flow discretized by Finite-Volume or Finite-Element-Methods. This review will illuminate current trends and recent progress within the area. In summary, the ultimate simulation model satisfying all physiological needs and scientific opinions still has to be developed.
In the human phonation process, acoustic standing waves in the vocal tract can influence the fluid flow through the glottis as well as vocal fold oscillation. To investigate the amount of acoustic ...back-coupling, the supraglottal flow field has been recorded via high-speed particle image velocimetry (PIV) in a synthetic larynx model for several configurations with different vocal tract lengths. Based on the obtained velocity fields, acoustic source terms were computed. Additionally, the sound radiation into the far field was recorded via microphone measurements and the vocal fold oscillation via high-speed camera recordings. The PIV measurements revealed that near a vocal tract resonance frequency
, the vocal fold oscillation frequency
(and therefore also the flow field's fundamental frequency) jumps onto
. This is accompanied by a substantial relative increase in aeroacoustic sound generation efficiency. Furthermore, the measurements show that
-
-coupling increases vocal efficiency, signal-to-noise ratio, harmonics-to-noise ratio and cepstral peak prominence. At the same time, the glottal volume flow needed for stable vocal fold oscillation decreases strongly. All of this results in an improved voice quality and phonation efficiency so that a person phonating with
-
-coupling can phonate longer and with better voice quality.
Modeling fluid-structure-acoustic interaction is a highly challenging task and currently there is a lack of available benchmark datasets. For instance, to understand the processes of human phonation, ...it is essential to fully understand the fluid-structure-acoustic interaction process. In this article, a synthetic human phonation model is presented for benchmarking numerical methods in the field of aerodynamics, aeroacoustics and the highly-complex fluid-structure-acoustic interaction process of the voice production. The objective is to present the wide range of experimental data available, including the model geometry, the material characteristics, quantitiesreferred to the vocal fold dynamics, fluid mechanical quantities and the acoustic field. Firstly, the experimental setup is specified. Secondly, the experimental data is described in detail, accompanied by illustrations. Having the dataset in hand, finally, it is shown how to use this data to validate a computational phonation model called simVoice successfully. In conclusion, this benchmarking dataset offers the opportunity to validate structural dynamics, aerodynamics and aeroacoustics of a highly-complex fluid-structure-acoustic interaction simulation, obtained from different mathematical formulations and numerical procedures.
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