•Geological data confirms that Buyuk Menderes graben is a geothermal basin.•Previously used methodology for hydrocarbon basin analysis is adapted for a geothermal basin.•Present and probable ...prospects in the Buyuk Menderes basin are studied and evaluated.•Geothermal power potential of the Buyuk Menderes graben is estimated stochastically.
Turkey’s installed geothermal capacity for power generation as of December 2019 is 1500 MWe. Most of this installed capacity is generated by the power plants located in the Buyuk Menderes graben. Geologically Buyuk Menderes graben is a huge structure having several discovered geothermal resources and can be considered as a geothermal basin.
The aim of this study is to estimate the geothermal power potential of Buyuk Menderes graben. To achieve this object, a stochastic methodology, which is used to evaluate hydrocarbon-bearing basins, is adapted from the oil and natural gas industry. This methodology provides a way to quantify the geothermal potential in a range of possible values by evaluating the individual fields in the basin using stored heat technique. A total of 34 (21 proven and 13 probable occurrences) geothermal fields having medium to high temperature (T ≥ 100 °C) values are evaluated using the Monte Carlo Simulation technique. In these simulations, available geological, geochemical, geophysical data are used along with the data obtained from the drilled wells in the region.
The power potential (MWe) values for 21 proven fields in terms of P10, P50 and P90 values are determined to be 888, 1077 and 1311 MWe, respectively. Considering the 13 probable occurrences along with the proven fields, the lower and upper limits of the total power potential (P10 and P90) are 1156 and 1580 MWe, respectively. Moreover, the power potentials are also evaluated under the presence of uncertainty. By assigning 5/13, 6/13, and 7/13 probability values for the 13 probable occurrences, overall geothermal power potential P10 values are estimated as 1041, 1075, and 1101 MWe, respectively.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
Large experimental programmes in the fields of nuclear and particle physics search for evidence of physics beyond that explained by current theories. The observation of the Higgs boson completed the ...set of particles predicted by the standard model, which currently provides the best description of fundamental particles and forces. However, this theory's limitations include a failure to predict fundamental parameters, such as the mass of the Higgs boson, and the inability to account for dark matter and energy, gravity, and the matter-antimatter asymmetry in the Universe, among other phenomena. These limitations have inspired searches for physics beyond the standard model in the post-Higgs era through the direct production of additional particles at high-energy accelerators, which have so far been unsuccessful. Examples include searches for supersymmetric particles, which connect bosons (integer-spin particles) with fermions (half-integer-spin particles), and for leptoquarks, which mix the fundamental quarks with leptons. Alternatively, indirect searches using precise measurements of well predicted standard-model observables allow highly targeted alternative tests for physics beyond the standard model because they can reach mass and energy scales beyond those directly accessible by today's high-energy accelerators. Such an indirect search aims to determine the weak charge of the proton, which defines the strength of the proton's interaction with other particles via the well known neutral electroweak force. Because parity symmetry (invariance under the spatial inversion (x, y, z) → (-x, -y, -z)) is violated only in the weak interaction, it provides a tool with which to isolate the weak interaction and thus to measure the proton's weak charge
. Here we report the value 0.0719 ± 0.0045, where the uncertainty is one standard deviation, derived from our measured parity-violating asymmetry in the scattering of polarized electrons on protons, which is -226.5 ± 9.3 parts per billion (the uncertainty is one standard deviation). Our value for the proton's weak charge is in excellent agreement with the standard model
and sets multi-teraelectronvolt-scale constraints on any semi-leptonic parity-violating physics not described within the standard model. Our results show that precision parity-violating measurements enable searches for physics beyond the standard model that can compete with direct searches at high-energy accelerators and, together with astronomical observations, can provide fertile approaches to probing higher mass scales.
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KISLJ, NUK, SBMB, UL, UM, UPUK
Abstract Uncovering the full list of human ciliary genes holds enormous promise for the diagnosis of cilia-related human diseases, collectively known as ciliopathies. Currently, genetic diagnoses of ...many ciliopathies remain incomplete (1–3). While various independent approaches theoretically have the potential to reveal the entire list of ciliary genes, approximately 30% of the genes on the ciliary gene list still stand as ciliary candidates (4,5). These methods, however, have mainly relied on a single strategy to uncover ciliary candidate genes, making the categorization challenging due to variations in quality and distinct capabilities demonstrated by different methodologies. Here, we develop a method called CilioGenics that combines several methodologies (single-cell RNA sequencing, protein-protein interactions (PPIs), comparative genomics, transcription factor (TF) network analysis, and text mining) to predict the ciliary capacity of each human gene. Our combined approach provides a CilioGenics score for every human gene that represents the probability that it will become a ciliary gene. Compared to methods that rely on a single method, CilioGenics performs better in its capacity to predict ciliary genes. Our top 500 gene list includes 258 new ciliary candidates, with 31 validated experimentally by us and others. Users may explore the whole list of human genes and CilioGenics scores on the CilioGenics database (https://ciliogenics.com/).
The Cimbicidae is a small family of the primitive and relatively less diverse suborder Symphyta (Hymenoptera). Here, nearly complete mitochondrial genome (mitogenome) of hairy sawfly,
Corynis ...lateralis
(Hymenoptera: Cimbicidae) was sequenced using next generation sequencing and comparatively analysed with the mitogenome of
Trichiosoma anthracinum
. The sequenced length of
C. lateralis
mitogenome was 14,899 bp with an A+T content of 80.60%. All protein coding genes (PCGs) are initiated by ATN codons and all are terminated with TAR or T− stop codon. All tRNA genes preferred usual anticodons. Compared with the inferred insect ancestral mitogenome, two tRNA rearrangements were observed in the IQM and ARNS1EF gene clusters, representing a new event not previously reported in Symphyta. An illicit priming of replication and/or intra/inter-mitochondrial recombination and TDRL seem to be responsible mechanisms for the rearrangement events in these gene clusters. Phylogenetic analyses confirmed the position of
Corynis
within Cimbicidae and recovered a relationship of Tenthredinoidea + (Cephoidea + Orussoidea) in Symphyta.
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EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OBVAL, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
Objective: This study aimed to compare the clinical efficacy and survival rates of the hall technique (HT), and conventional restoration (CR) for the management of occlusoproximal carious lesions in ...primary molars. Materials and Methods: This clinical study observed 35 children (aged 4-8 years). Exclusion criteria included symptoms of pulpal or periradicular pathology or systemic conditions requiring special dental considerations. For each child, at least one tooth was treated with HT and one with CR. The primary outcome measures were minor and major clinical failure rates. Plaque and gingival scores of the teeth were also evaluated. Friedman test and Wilcoxon signed ranks test were used to compare the plaque and gingival index scores for each arm. Chi-square tests were used for comparisons of clinical outcomes, plaque-gingival index, and distribution of ICDAS categories among treatment arms (P < 0.05). Results: Thirty-three of 35 (94.2%) participants returned for 1-year follow-up. HT showed statistically significantly higher treatment survival rate and fewer minor failures than CR (P = 0.040). The rate of major failures was minimal (2 of 84 teeth) and did not differ between treatments (P = 0.092). In both treatment groups, the gingival score and plaque score were significantly decreased at the 1-year follow-up (P < 0.05). Conclusion: HT was a more successful method for managing caries in primary molars than CR, both for symptoms of pulpal disease and longevity of the restorations. HT is a simplified method of managing carious primary molars using SSCs cemented with no local anesthesia, caries removal, or tooth preparation.
AIM: Chorthippus parallelus is one of the classic model systems for studying genetic structure and phylogeography in the Western Palaearctic. Here, we investigate the regional genetic differentiation ...of C. parallelus and evaluate the historical and evolutionary processes responsible for such genetic structuring, test the nature of the Turkish Straits system as a barrier to dispersal, and explore the contribution of Anatolian populations to the biodiversity of the Western Palaearctic. LOCATION: Western Palaearctic. METHODS: We incorporated sequence data from dense sampling of the phylogeographically important Anatolian region with both previous and newly obtained data of the nuclear fragment cpnl‐1 and the mitochondrial fragment COI–tRNALeu–COII. In total, 1049 sequences of cpnl‐1 from 33 regions were analysed to investigate the genetic diversity, genetic structuring and phylogeography of C. parallelus across its distributional range. The mtDNA region was additionally used to test whether the Turkish Straits system acts as a barrier. RESULTS: The analyses revealed that not all southern refugial populations of C. parallelus have contributed equally to the post‐glacial recolonization of Europe. Four genetic clusters across the species' range were recovered: cluster A (eastern part of the Anatolian Diagonal); cluster B (western part of the Anatolian Diagonal); cluster C (Spain, Italy, southern Balkans, west part of Anatolia and Russia); and cluster D (covering the entire distributional range of the species). The Turkish Straits system has been a weak barrier to dispersal by C. parallelus, allowing gene flow from Anatolia to the Balkans. MAIN CONCLUSIONS: The current patterns of genetic structuring of C. parallelus were best explained by multiple expansion and contraction events. Anatolia has been well connected to the Balkans, contributing genetically to the establishment of central and northern European populations prior to the Holocene. The Anatolian refugium is suggested to be the centre of origin for Western Palaearctic C. parallelus diversity rather than a Balkan refugium.
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BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NMLJ, NUK, OILJ, PNG, SAZU, SBCE, SBMB, UL, UM, UPUK
Increasing activities of geothermal development especially in the last three years result in a geothermal boom in Turkey. Not only the addition of new sites, but also updating the data of existing ...ones increased the currently identified capacity significantly. With the discoveries of 13 new geothermal fields, power potentials increased by 1.6 times.
This study deals with hydrothermal and EGS potentials of Turkey. The geothermal resource base between 0 and 3km depth in Turkey and the capacity of the currently identified 290 geothermal sites are determined to be 3.96×1023J and 10,576MWt, respectively.
As of today, a total of 135 hydrothermal fields were individually studied, of which 38 medium to high temperature (T≥100°C) fields were simulated to estimate the power generation. The remaining 97 fields were simulated to estimate the direct use potentials. The lower and upper limits of power generation potential corresponding to P10 and P90 values are 1673 and 3140MWe, respectively. Moreover, the lower and upper thermal potential limits of 135 hydrothermal fields corresponding to P10 and P90 values are 38.2 and 68.4GWt, respectively.
•Capacity of identified resources is calculated.•The geothermal resource base in Turkey is determined.•Turkey’s potential for geothermal electricity generation is estimated.•The thermal potential for identified fields is estimated.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
A new mathematical model described by a Volterra integrodifferential equation (VIDE) with constant delay is examined. New agreeable conditions on the uniformly asymptotic stability, boundedness, and ...square integrability of solutions of the VIDE are obtained by using the Lyapunov–Razumikhin technique. The established conditions improve some former results. They can be also regarded as nonlinear generalizations of these results. Moreover, they are weaker than some available results cited in the bibliography. Two examples are presented to demonstrate possible applications of these results and the introduced concepts. The application of the Lyapunov–Razumikhin technique leads to a significant difference and gives certain advantages over the related methods used in the books and papers cited in the bibliography.
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DOBA, EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, IZUM, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UILJ, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
Two complete mitogenomes of the stem borers, Calameuta filiformis and Calameuta idolon, and the complete A+T-rich region of Trachelus iudaicus (Hymenoptera: Cephidae), are reported. The mitogenomes ...of these species are the longest reported from hymenopterans to date. A remarkable increase in length of the A+T-rich region, the longest for Hymenoptera, was found and compared across the tribe Cephini. The presence of the tRNA- and rRNA-like sequences were reported in the A+T-rich region of sawflies and they were suggested to play a role in replication and/or transcription. The long and short tandem repeats were orderly located in both sides of the A+T-rich region producing stable secondary structures. We suggest that the short tandem repeats are likely to function as a replication fork barrier.
•The complete mitogenomes of stem borers, Calameuta filiformis and Cl. idolon, are sequenced and characterised.•A rearrangement in IQM gene cluster and a length expansion in rrnS gene are suggested as synapomorphies for Cephini.•A remarkable length increase is also observed in their A+T rich region.•Characterisation of the A+T-rich region reveals the presence of the tRNA- and rRNA-like sequences and tandem repeats.•Short tandem repeats are suggested replication fork barrier in insects for the first time.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK, ZRSKP
Purpose: In this study, it is aimed to determine theperceptions of the patients receiving hemodialysistreatment about the nursing care they receive and toinvestigate the factors affecting this ...perception.Materials and Methods: This research was plannedas a descriptive study by using quantitative researchmethods. The sample of the study consisted of 50patients who were diagnosed with chronic renalfailure and received hemodialysis treatment in ahospital operating in the province of Kayseri.Results: It was determined that the mean age of thehemodialysis patients included in the study was60.2313.60 years and the gender of 54 % was male(n=27). The total mean score of hemodialysispatients from the "Patient's Perception of NursingCare" scale is 68.317.38.Conclusions: As a result of our study, it wasdetermined that the patients' perception of care andthus their care satisfaction were at a high level.
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IZUM, KILJ, NUK, ODKLJ, PILJ, PNG, SAZU, UL, UM, UPUK
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