The Baksan Experiment on Sterile Transitions (BEST) was designed to investigate the deficit of electron neutrinos νe observed in previous gallium-based radiochemical measurements with high-intensity ...neutrino sources, commonly referred to as the "gallium anomaly," which could be interpreted as evidence for oscillations between νe and sterile neutrino (νs) states. A 3.414-MCi 51Cr νe source was placed at the center of two nested Ga volumes and measurements were made of the production of 71Ge through the charged current reaction, 71Ga(νe,e-)71Ge, at two average distances. The measured production rates for the inner and the outer targets, respectively, are 54.9$_{-2.4}^{+2.5}$(stat)±1.4(syst) and 55.6$_{-2.6}^{+2.7}$(stat)±1.4(syst) atoms of 71Ge/d. The ratio (R) of the measured rate of 71Ge production at each distance to the expected rate from the known cross section and experimental efficiencies are Rin=0.79±0.05 and Rout=0.77±0.05. The ratio of the outer to the inner result is 0.97±0.07, which is consistent with unity within uncertainty. The rates at each distance were found to be similar, but 20%-24% lower than expected, thus reaffirming the anomaly. Therefore these results are consistent with νe→νs oscillations with a relatively large Δm2 (> 0.5 eV2) and mixing sin22θ (≈0.4).
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Introduction
Alcohol withdrawal delirium is severe complication of alcohol withdrawal leading to high mortality. Early identification of severe course of psychosis and complications threatening the ...patient’s life is the most important problem in the treatment of these patients.
Objectives
Under supervision were 690 men, dependent on alcohol, in the state of withdrawal with acute psychotic disorder (primary hospitalization in the framework of this study); the average age - (39,9 ± 3,4 years), the average age of alcohol abuse - (9,7 ± 1, 1 years). The patients were examined in a dynamics after a re-hospitalization after 5-7 years. This allowed us to verify the differential diagnostic approach to acute psychotic disorders in a state of abandonment, to investigate the impact of chronic acute psychotic disorders on the course of alcohol dependence, including the formation of deficits.
Methods
clinical, clinical and psychopathological, methods of quantified scales and mathematical statistics.
Results
There were estimated factors influencing the severity of alcohol withdrawal with delirium: total amount of alcohol consumed per week, drunken alcoholics, persistent alcohol abuse, social disadaptation, cognitive impairment, psychological disorders, reducing the quality of alcohol consumed, food pattern characterized total calorie mostly due to alcohol, life trajectory, severe or chronic somatic diseases, rate of progression of alcohol dependence.
Conclusions
The severity of acute psychotic disorder in the state of alcohol withdrawal mostly depended situational factors such as the number of days of severe drinking before a psychotic disorder, the pattern of nutrition, the quality and quantity of alcohol consumed, the presence of acute somatic diseases.
Disclosure
No significant relationships.
Introduction
Withdrawal states with delirium, having convulsive syndrome in their structure, are one of the most severe emergency conditions in psychiatry.
Objectives
A total of 160 patients were ...examined with delirium alcohol withdrawal. Prognostic factors of occurrence of convulsive syndrome in the withdrawal syndrome of alcohol were studied.
Methods
Clinical, psychopathological, electrophysiological.
Results
It was found that the most significant prognostic factors seizures were: severe bloating condition, the duration of hard drinking, the total dose of drinking alcohol before the breakdown of consumption alcohol. Convulsive syndrome not always correlated with marked vegetative disorders in the state of withdrawal of alcohol. Convulsive syndrome that appeared after the development of delirious syndrome often indicated a more serious conditionIt is suggested that the convulsive pattern of response to the severe condition of alcohol withdrawal is formed in some young patients under the influence of endogenous factors, but is realized under certain situational conditions - long binge drinking, massive consumption o alcohol before the break of the reception of alcohol, the use of psychoactive drugs with stimulating effect. In the electrophysiological examination, there were significant differences in the group of patients with convulsive syndrome in the current admission from the group of patients with convulsive syndrome in the past and the group without convulsive syndrome in the state of abolition of alcohol.
Conclusions
It is emphasized that when indicating the seizures in the state of abolition of alcohol in the past, the beginning of treatment is necessary to begin even in a state of binge drinking.
Introduction
Severe acute psychosis significantly alters patient’s quality of life in patients with alcohol dependence. The aim of the investigation were examination value quality of the life ...patients with alcohol dependence who have recently suffered of acute psychotic disorder. The factor influencing the quality of life is the psychoorganic syndrome after acute psychosis.
Objectives
120 patients with alcohol dependence who had recent history of acute psychosis were examined.
Methods
Psychopathological.
Results
The psychorganic syndromes at these patients were investigated. The Index quality of the life in these patients was assessed due to type of the psychorganic syndromes. The dynamics of the Index quality of the life at patients with psychorganic syndrome during the treatment were described. The subjective assessment of their condition in patients with hard psychorganic syndrome was dissociated from the assessment of doctors and relatives. The explaining the characteristics of the consequences of the transferred psychotic disorder to the patients turned out to be important for overcoming anosognosia. The Index quality of the life in these patients was assessed repeatedly at the same time, there was a significant decrease in the difference in the assessment of the quality of life by patients with relatives.
Conclusions
The importance of value quality of the life from the point of the patient, relatives of the patient and physician was underlined. The assesment of Index quality of the life is important important to explain the peculiarities of the postpsychotic state to the patients and their relatives in order to develop rehabilitation programs and carrying out psychotherapeutic activities.
Introduction
As a result of Russia’s large-scale military aggression against Ukraine, many civilians were forced to leave their homes. Emotional disorders associated with fear for one’s life and ...relatives, loss of housing, work, and stable social ties are found in the majority of forcibly displaced persons.
Objectives
The purpose of our study was to study the characteristics and expressiveness of affective disorders in displaced persons as a result of Russian aggression against Ukraine. Studied affective disorders in 24 forcibly displaced females. Age of the surveyed 30-50 years. Contacted with psychiatrist because the insistence of relatives. Patients were not identified and applied earlier about mental disorders to psychiatrists. To quantify anxiety, we used a scale HAM-A.
Methods
Clinico-psychopathological.
Results
Affective disorders in the examined patients can be confidently attributed to adjustment disorders. According to the ICD-10, an adaptation disorder (F43.2) was diagnosed. Most of them were dominated by depressive and anxiety-depressive modalities of affective disorders. According to the HAM-A scale, the level of anxiety was 14
±
2.7. Most patients showed few irritability and anger, which is probably due to the inability to respond to the cause of their troubles and problems. However, some patients (6 people) expressed gloomy irritability, anger (clinical sighnificant) a feeling of hostility towards others. It is necessary to note the undulation of these manifestations, often aggravated under the influence of external factors.At the same time, the immediate environment often suffered, on which all the troubles fell. The behavior of such patients became maladaptive, significantly disrupting communication.
Conclusions
Therapeutic impact on internally displaced persons should be aimed not only at overcoming anxiety and depressive syndrome, but also irritability and anger. This should be taken into account when planning psychotherapeutic programs, it is possible to prescribe normotimics.
Disclosure of Interest
None Declared
The GERmanium Detector Array (GERDA) experiment searched for the lepton-number-violating neutrinoless double-β (0νββ) decay of ^{76}Ge, whose discovery would have far-reaching implications in ...cosmology and particle physics. By operating bare germanium diodes, enriched in ^{76}Ge, in an active liquid argon shield, GERDA achieved an unprecedently low background index of 5.2×10^{-4} counts/(keV kg yr) in the signal region and met the design goal to collect an exposure of 100 kg yr in a background-free regime. When combined with the result of Phase I, no signal is observed after 127.2 kg yr of total exposure. A limit on the half-life of 0νββ decay in ^{76}Ge is set at T_{1/2}>1.8×10^{26} yr at 90% C.L., which coincides with the sensitivity assuming no signal.
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Introduction
The psychoses in patients with dependence of alcohol are in many cases polyethiologic, this is especially common in the elderly due to accumulation of various somato-neurological ...pathologies.
Objectives
88 men, with alcohol withdrawal syndrome accompanied by delirium; the average age - 70,4 ± 3,9 years, duration of alcohol abuse - 27,4 ± 6,5 years.
Methods
clinical, psychopathological and statistical
Results
The psychoses in patients with dependence of alcohol are in many cases polyethiologic, this is especially common in elderly due to accumulation of various somato-neurological pathologies. One of such factors is alcohol dependence syndrome and alcohol withdrawal. ICD-10 allows sharing out delirium with mixed etiology F05.8; this category can include patients when there is a severe alcohol withdrawal condition and somato-neurological pathology that can be an independent factor in the delirious syndrome. 88 elderly patients with were examined in state of alcohol withdrawal. All patients had delirious syndrome. Patients were divided into 2 groups: 1st – patients with a condition of alcohol withdrawal with delirium; 2nd - patients with a delirium of mixed etiology (the factor of the presence of dyscirculatory encephalopathy, was considered a competing factor in the onset of delirium). Some differential-diagnostic signs of the studied disorders were established. In the case of prolongation of psychosis, the clinical picture was similar in both groups, which was explained by exacerbation of the existing somatic pathology.
Conclusions
Estimation of the leading factor in the emergency of acute psychosis in patients with alcohol withdrawal syndrome is of great practical importance for selection of therapeutic tactics.
Probing Majorana neutrinos with double-β decay Agostini, M; Bakalyarov, A M; Balata, M ...
Science (American Association for the Advancement of Science),
09/2019, Volume:
365, Issue:
6460
Journal Article
Peer reviewed
Open access
A discovery that neutrinos are Majorana fermions would have profound implications for particle physics and cosmology. The Majorana character of neutrinos would make possible the neutrinoless double-β ...(0νββ) decay, a matter-creating process without the balancing emission of antimatter. The GERDA Collaboration searches for the 0νββ decay of
Ge by operating bare germanium detectors in an active liquid argon shield. With a total exposure of 82.4 kg⋅year, we observe no signal and derive a lower half-life limit of
> 0.9 × 10
years (90% C.L.). Our
sensitivity, assuming no signal, is 1.1 × 10
years. Combining the latter with those from other 0νββ decay searches yields a sensitivity to the effective Majorana neutrino mass of 0.07 to 0.16 electron volts.
Introduction
The social consequences of alcohol affect not only drinkers, but also the people communicate with him. They are including: mental health, quality of life, health, living conditions and ...needs in using health system resources.
Objectives
1,531 people were examined, who belonged to three qualitatively different comparison groups: patients with alcohol addiction (329 people); healthy relatives of patients with alcohol addiction (238 persons) and representatives of the general population (964 persons).
Methods
clinical, clinical and psychopathological, methods of quantified scales and mathematical statistics.
Results
The data obtained indicate that the majority of respondents who caused some harm to the respondents were men. But the level of harm of alcohol abuse of women was significantly higher. Alcohol abuse problems of microsocial environment (substance abuse, employment, financial problems, and health effects) had a more significant effect on depressive disorders in the control group than in the alcohol addiction group and their relatives. Significant correlation of depressive disorders due to the drunkenness of others was associated with fear for children, the possibility of aggression. Depressive disorders in the group relatives of patients with alcohol addiction correlated with aggression towards them with patients with alcohol addiction or persons in a state of alcohol intoxication, discomfort due to being with their relatives in public, at parties, inability to control alcohol use. It was shown that the presence of drinkers in the company of women significantly increases the specific weight of people with depressive disorders among them, while such an effect was not found among male respondents. It has been established that in the case of the presence of drinkers in the environment, the expressiveness of such manifestations of depression as insomnia increases the most in women; weight loss, sexual disorders; suicidal tendencies and feelings of guilt. The influence of presence of drinkers in the environment of children on tfrequency of manifestations of their discomfort is described. It has been confirmed that the most frequent cause of children’s ill health is their drinking parents, as well as other (besides parents and siblings) drinking relatives. It was found that in healthy respondents, the unfavorable features of the behavior of relatives and close drinkers are always directly correlated with indicators of the ill health of children in their environment, while in respondents addicted to alcohol, these correlations have a complex, mosaic nature.
Conclusions
The study found the prevalence of depressive disorders in the microsocial environment of drinkers. A significant decrease in the quality of life was noted primarily in children and women who had drinking relatives with a large number of drunk days.
Disclosure of Interest
None Declared
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