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  • Resolvin D1 and E1 promote ... Resolvin D1 and E1 promote resolution of inflammation in microglial cells in vitro
    Rey, C; Nadjar, A; Buaud, B ... Brain, behavior, and immunity, 07/2016, Volume: 55
    Journal Article
    Peer reviewed

    Highlights • Our work is the first to show that RvD1 and RvE1 are potent inhibitors of LPS-induced TNF-α, IL-6 and IL-1β gene expression. • RvD1 and RvE1 are modulators of microglial phenotype in ...
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  • Essential omega-3 fatty aci... Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain
    Madore, C; Leyrolle, Q; Morel, L ... Nature communications, 11/2020, Volume: 11, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Omega-3 fatty acids (n-3 PUFAs) are essential for the functional maturation of the brain. Westernization of dietary habits in both developed and developing countries is accompanied by a progressive ...
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  • Dietary n-3 long chain PUFA... Dietary n-3 long chain PUFA supplementation promotes a pro-resolving oxylipin profile in the brain
    Rey, C.; Delpech, J.C.; Madore, C. ... Brain, behavior, and immunity, February 2019, 2019-02-00, 20190201, 2019-02, Volume: 76
    Journal Article
    Peer reviewed
    Open access

    •Dietary n-3 LC-PUFA supplementation modulates hippocampal oxylipins profile.•Dietary n-3 LC-PUFA supplementation decreases hippocampal pro-inflammatory cytokines induced by LPS.•Oxylipin profile ...
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  • How French subjects describ... How French subjects describe well-being from food and eating habits? Development, item reduction and scoring definition of the Well-Being related to Food Questionnaire (Well-BFQ©)
    Guillemin, I.; Marrel, A.; Arnould, B. ... Appetite, 01/2016, Volume: 96
    Journal Article
    Peer reviewed

    Providing well-being and maintaining good health are main objectives subjects seek from diet. This manuscript describes the development and preliminary validation of an instrument assessing ...
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  • Direct and indirect effects... Direct and indirect effects of lipids on microglia function
    Leyrolle, Q.; Layé, S.; Nadjar, A. Neuroscience letters, 08/2019, Volume: 708
    Journal Article
    Peer reviewed
    Open access

    •Fatty acids can modulate microglia function across lifetime.•Lipids influence microglia through direct and indirect mechanisms.•Dietary lipids could represent a novel modifiable factor in diseases ...
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  • 119. Immune-to-brain intera... 119. Immune-to-brain interactions in metabolic disorders
    Capuron, L; Layé, S Brain, behavior, and immunity, September 2013, Volume: 32
    Journal Article
    Peer reviewed

    Immune-to-brain interactions are known to play a role in the pathophysiology of behavioral symptoms. Pro-inflammatory cytokines released by activated immune cells are notorious for causing ...
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  • Abstract # 1806 Effect of a... Abstract # 1806 Effect of an omega-3 and antioxidants supplemented diet on emotional and cognitive alterations and neuroinflammatory processes associated with obesity
    Fourrier, C; Bosch-Bouju, C; Sauvant, J ... Brain, behavior, and immunity, 10/2016, Volume: 57
    Journal Article
    Peer reviewed

    Obesity is a metabolic and inflammatory disorder that represents a major risk factor for development of comorbidities such as cardiovascular diseases or diabetes. Obese patients also often experience ...
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  • Food for mood: Relevance of... Food for mood: Relevance of nutritional Omega-3 fatty acids for depression and anxiety
    Laye, S. European psychiatry, 04/2021, Volume: 64, Issue: S1
    Journal Article
    Peer reviewed
    Open access

    Polyunsaturated fatty acids (PUFAs) are essential fatty acids which are provided to the body through the diet. The brain is one of the richest organs in the body and has a high need in PUFAs. There ...
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  • Neuro-inflammation dans les... Neuro-inflammation dans les maladies neurologiques. Rôle des probiotiques
    Joffre, C.; Dinel, A.L.; Layé, S. Phytothérapie (Paris, France), 12/2018, Volume: 16, Issue: 6
    Journal Article
    Peer reviewed

    Le microbiote intestinal est un acteur clé de la communication entre les intestins et le cerveau et pourrait participer à la physiopathologie de plusieurs maladies du système nerveux, dont les ...
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