In our Letter (Phys. Rev. Lett. vol. 125, 013903 (2020)), we reported topological vortex lasers based on spin-momentum-locked edge modes. We observed that the near field spin and orbital angular ...momentum has a one-to-one far-field radiation correspondence of circular polarization and orbital angular momentum respectively. Sun et al. in their Comment (arXiv:2009.04700v1), however, argued that we did not perform numerical simulations on the near field information of our experimentally studied topological edge modes, and our mode assignment was mistaken and spoiled the one-to-one correspondence. However, we will show that their arguments are wrong. Furthermore, we will show that the Eqs. (1) and (2) and the phase windings in their Comment are wrong.
Spin-Momentum-Locked Edge Mode for Topological Vortex Lasing Yang, Zhen-Qian; Shao, Zeng-Kai; Chen, Hua-Zhou ...
2020 Asia Communications and Photonics Conference (ACP) and International Conference on Information Photonics and Optical Communications (IPOC),
2020-Oct.
Conference Proceeding
High performance topological bulk lasers Shao, Zeng-Kai; Chen, Hua-Zhou; Wang, Suo ...
2020 Asia Communications and Photonics Conference (ACP) and International Conference on Information Photonics and Optical Communications (IPOC),
2020-Oct.
Conference Proceeding
It is of keen interest to researchers understanding different approaches to confine massless Dirac fermions in graphene, which is also a central problem in making electronic devices based on ...graphene. Here, we studied spatial confinement, magnetic localization and their interactions on massless Dirac fermions in an angled graphene wedge formed by two linear graphene p-n boundaries with an angle 34. Using scanning tunneling microscopy, we visualized quasibound states temporarily confined in the studied graphene wedge. Large perpendicular magnetic fields condensed the massless Dirac fermions in the graphene wedge into Landau levels (LLs). The spatial confinement of the wedge affects the Landau quantization, which enables us to experimentally measure the spatial extent of the wave functions of the LLs. The magnetic fields induce a sudden and large increase in energy of the quasibound states because of a pi Berry phase jump of the massless Dirac fermions in graphene. Such a behavior is the hallmark of the Klein tunneling in graphene. Our experiment demonstrated that the angled wedge is a unique system with the critical magnetic fields for the pi Berry phase jump depending on distance from summit of the wedge.
Ordered atomic-scale superlattices on surface hold great interest both for basic science and for potential applications in advanced technology. However, controlled fabrication of superlattices down ...to atomic scale has proven exceptionally challenging. Here we demonstrate the segregation-growth and self-organization of ordered S atomic superlattices confined at the interface between graphene and S-rich Cu substrates. Scanning tunneling microscope (STM) studies show that, by finely controlling the growth temperature, we obtain well-ordered S (sub)nanometer-cluster superlattice and monoatomic superlattices with various periods at the interface. These atomic superlattices are stable in atmospheric environment and robust even after high-temperature annealing (~ 350 oC). Our experiments demonstrate that the S monoatomic superlattice can drive graphene into the electronic Kekulé distortion phase when the period of the ordered S adatoms is commensurate with graphene lattice. Our results not only open a road to realize atomic-scale superlattices at interfaces, but also provide a new route to realize exotic electronic states in graphene.
Three-dimensional（3D） printing（3DP） is a rapid prototyping technology that has gained increasing recognition in many different fields. Inherent accuracy and low-cost property enable applicability of ...3DP in many areas, such as manufacturing, aerospace,medical, and industrial design. Recently, 3DP has gained considerable attention in the medical field. The image data can be quickly turned into physical objects by using 3DP technology. These objects are being used across a variety of surgical specialties. The shortage of cadaver specimens is a major problem in medical education. However, this concern has been solved with the emergence of 3DP model. Custom-made items can be produced by using 3DP technology. This innovation allows 3DP use in preoperative planning and surgical training. Learning is difficult among medical students because of the complex anatomical structures of the liver. Thus, 3D visualization is a useful tool in anatomy teaching and hepatic surgical training. However,conventional models do not capture haptic qualities. 3DP can produce highly accurate and complex physical models. Many types of human or animal differentiated cells can be printed successfully with the development of 3D bio-printing technology. This progress represents a valuable breakthrough that exhibits many potential uses, such as research on drug metabolism or liver disease mechanism. This technology can also be used to solve shortage of organs for transplant in the future.
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FFLJ, IZUM, KILJ, NUK, ODKLJ, PILJ, PNG, SAZU, UL, UM, UPUK
Background： Spinocerebellar ataxia type 3 （SCA3） is the most common subtype of SCA worldwide, and runs a slowly progressive and unremitting disease course. There is currently no curable treatment ...available. Growing evidence has suggested that nerve growth factor （NGF） may have therapeutic effects in neurodegenerative diseases, and possibly also in SCA3. The objective of this study was to test the efficacy of NGF in SCA3 patients. Methods： We performed an open-label prospective study in genetically confirmed adult （〉18 years old） SCA3 patients. NGF was administered by intramuscular injection （18 μg once daily） fbr 28 days consecutively. All the patients were evaluated at baseline and 2 and 4 weeks after treatment using the Chinese version of the scale for assessment and rating of ataxia （SARA）. Results： Twenty-one SCA3 patients （ 10 men and 11 women, mean age 39.14 ± 7.81 years, mean disease duration 4.14 ± 1.90 years, mean CAG repeats number 77,57 ± 2.27） were enrolled. After 28 days of NGF treatment, the mean total SARA score decreased significantly from a baseline of 8.48± 2.40 to 6.30 ± 1.87 （P 〈 0.001 ）. Subsections SARA scores also showed significant improvements in stance （P = 0.003）, speech （P = 0.023）, finger chase （P = 0.015）, fast alternating hand movements （P = 0.009）, and heel-shin slide （P = 0.001）. Conclusions： Our preliminary data suggest that NGF may be effective in treating patients with SCA3.
Background Exhaled nitric oxide （NO） is a noninvasive biomarker of airway inflammation in pulmonary diseases. Hydrogen sulfide （H2S）, as the third member of the gasotransmitter family, is involved in ...the pathophysiological process in lung diseases. H2S also exists in exhaled breath and can be sampled non-invasively. The study investigated the level of exhaled H2S in patients with chronic obstructive pulmonary disease （COPD） and its correlation with exhaled NO. Methods Levels of exhaled NO and H2S, lung function, and cell differential counts in induced sputum were studied in 19 patients with acute exacerbation of COPD （AECOPD）, 19 patients with stable COPD and seven healthy smoke controls. Results Exhaled H2S levels were similar in patients with AECOPD （10.0 parts per billion （ppb）, 8.0-13.0 ppb）, stable COPD （10.0 ppb, 9.0-12.0 ppb）, and healthy controls （9.0 ppb, 8.0-16.0 ppb） （P 〉0,05）. Exhaled NO levels were similar in patients with AECOPD （155.0 ppb, 129.0-190.0 ppb）, stable COPD （154.0 ppb, 133.0-175.0 ppb） and healthy controls （165.0 ppb, 112.0-188.0 ppb） （P 〉0.05）. Exhaled H2S levels correlated positively with exhaled NO in all healthy controls and patients with COPD （r=0.467, P 〈0.01）. No significant correlation was found between the exhaled H2S level and percentage of predicted FEV1 （P 〉0.05） and proportion of different cell types in induced sputum （P 〉0.05）. Conclusions There is a correlation between exhaled H2S and exhaled NO. The role of exhaled H2S in airway inflammation in COPD still needs further investigation.
Background： The liver is the most common site for colorectal cancer （CRC） metastases. Their removal is a critical and challenging aspect of CRC treatment. We investigated the prognosis and risk ...factors of patients with CRC and liver metastases （CRCLM） who underwent simultaneous resections for both lesions. Methods： From January 2009 to August 2016, 102 patients with CRCLM received simultaneous resections of CRCLM at our hospital. We retrospectively analyzed their clinical data and analyzed their outcomes. Overall survival （OS） and disease-free survival （DFS） were examined by Kaplan-Meier and log-rank methods. Results： Median follow-up time was 22.7 months： no perioperative death or serious complications were observed. Median OS was 55.5 months： postoperative OS rates were l-year： 93.8%, 3-year： 60.7%, and 5-year： 46.4%. Median DFS was 9.0 months; postoperative DFS rates were l-year： 43.1%, 3-year： 23.0%, and 5-year 21.1%. Independent risk factors found in multivariate analysis included carcinoembryonic antigen 〉100 ng/ml, no adjuvant chemotherapy, tumor thrombus in liver metastases, and bilobar liver metastases for OS; age 〉60 years, no adjuvant chenlotherapy, multiple metastases, and largest diameter ≥3 cm for DFS. Conclusions： Simultaneous surgical resection is a safe and effective treatment for patients with synchronous CRC LM. The main prognostic factors are pathological characteristics of liver metastases and whether standard adjuvant chemotherapy is performed.
AIM: To determine the extent of colorectal cancer(CRC) mortality and the association between demographic characteristics and CRC mortality in Inner Mongolia.METHODS: Data were collected from the ...Death Registry System, maintained by the Inner Mongolia Centers for Disease Control and Prevention, from 2008 to 2012. Deaths were classified according to the International Classification of Disease, 10th Revision. Years of life lost, average years of life lost(AYLL), and mortality were calculated over the five years between 2008 and 2012. A conditional logistic regression model was used to analyze the association between marital status, occupational status, education level, area of residence, and the risk of CRC.RESULTS: The AYLL of CRC was 17.39 years. The average mortality of CRC was 5.6/100000. People living in urban areas and having a higher education level had a significantly higher risk of CRC(OR = 1.74 and 95%CI: 1.29-2.35, P < 0.001 and OR = 2.39, 95%CI: 1.76-3.25, P < 0.001, respectively). People who were employed had a lower risk of CRC(OR = 0.64, 95%CI: 0.48-0.86, P = 0.003). The mortality of CRC was positively correlated with the education level(P < 0.001). No statistically significant association was observed between marital status and CRC risk(P = 0.259).CONCLUSION: Living in urban areas, higher education level and unemployment are associated with CRC mortality in Inner Mongolia.
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