Abstract Background The body mass index (BMI) is based on the original concept that body weight increases as a function of height squared. As an indicator of obesity the modern BMI assumption ...postulates that adiposity also increases as a function of height in states of positive energy balance. Objective To evaluate the BMI concept across different adiposity magnitudes, in both children and adults. Methods We studied 975 individuals who underwent anthropometric evaluation: 474 children and 501 adults. Tetrapolar bioimpedance analysis was used to assess body fat and lean mass. Results BMI significantly correlated with percentage of body fat (%BF; children: r = 0.893; adults: r = 0.878) and with total fat mass (children: r = 0.967; adults: r = 0.953). In children, body weight, fat mass, %BF and waist circumference progressively increased as a function of height squared. In adults body weight increased as a function of height squared, but %BF actually decreased with increasing height both in men ( r = −0.406; p < 0.001) and women ( r = −0.413; p < 0.001). Most of the BMI variance in adults was explained by a positive correlation of total lean mass with height squared ( r2 = 0.709), and by a negative correlation of BMI with total fat mass ( r = −0.193). Conclusions Body weight increases as a function of height squared. However, adiposity progressively increases as a function of height only in children. BMI is not an ideal indicator of obesity in adults since it is significantly influenced by the lean mass, even in obese individuals.
Abstract Background The body mass index (BMI) is based on the original concept that body weight increases as a function of height squared. As an indicator of obesity the modern BMI assumption ...postulates that adiposity also increases as a function of height in states of positive energy balance. Objective To evaluate the BMI concept across different adiposity magnitudes, in both children and adults. Methods We studied 975 individuals who underwent anthropometric evaluation: 474 children and 501 adults. Tetrapolar bioimpedance analysis was used to assess body fat and lean mass. Results BMI significantly correlated with percentage of body fat (%BF; children: r = 0.893; adults: r = 0.878) and with total fat mass (children: r = 0.967; adults: r = 0.953). In children, body weight, fat mass, %BF and waist circumference progressively increased as a function of height squared. In adults body weight increased as a function of height squared, but %BF actually decreased with increasing height both in men ( r = −0.406; p < 0.001) and women ( r = −0.413; p < 0.001). Most of the BMI variance in adults was explained by a positive correlation of total lean mass with height squared ( r2 = 0.709), and by a negative correlation of BMI with total fat mass ( r = −0.193). Conclusions Body weight increases as a function of height squared. However, adiposity progressively increases as a function of height only in children. BMI is not an ideal indicator of obesity in adults since it is significantly influenced by the lean mass, even in obese individuals.
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En este trabajo se optimizó la extracción de una bebida de banano por métodos enzimáticos en tres cultivares. Se emplearon dos enzimas comerciales: una amilasa (Glucozyme-400) y una combinación de ...celulasa, hemicelulasa y pectinasa (Macerex PM). Se optimizó el estado de madurez de la fruta, la variedad, el tipo de enzima y la dilución, usando como variables de respuesta la concentración de sólidos solubles (gradosBrix) y el rendimiento de la extracción. La enzima amilasa no mostró un efecto positivo en la extracción en ninguna etapa de madurez. El complejo Macerex PM presentó un efecto positivo en el rendimiento; sin embargo, al aumentar el factor de dilución disminuye el rendimiento y la concentración de sólidos solubles (gradosBrix).
Primary immunodeficiencies have a low prevalence, but their severity and high risk of mortality require a clinical approach based in diagnostic instruments that allow their early detection.
To ...validate the PRIDE scale to determine a high level of suspicion for primary immunodeficiency diseases in Mexican population.
Seventy five patients with suspicion of primary immunodeficiencies (13.9 ±11.8 years-old) were evaluated with the PRIDE scale by specialists in Allergy and Immunology in this cross-sectional study, and their results were compared with the confirmed diagnosis of primary immunodeficiency.
Kappa concordance coefficient with clinical diagnosis was 0.872, with an standard error of 0.072; CI 95% 0.73-1.013. The scale showed sensitivity 98.3%, specificity 86.6%, positive predictive value 96.7%, negative predictive value 92.8%, positive odds ratio 7.3358 and negative odds ratio 0.0196.
PRIDE scale was concordant with the diagnosis of primary immunodeficiency in the majority of patients with a previous confirmed diagnosis. The characteristics of diagnostic accuracy provide reliability to this instrument in the scrutiny of patients with probable immunodeficiency.
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56.
Back Matter Gabriela Dutrénit; José Miguel Natera; Martín Puchet Anyul ...
Procesos de diálogo para la formulación de políticas de CTI en América Latina y España,
01/2017
Book Chapter
ACERCA DE ESTA PUBLICACIÓN Gabriela Dutrénit; José Miguel Natera; Martín Puchet Anyul ...
Consejo Latinoamericano de Ciencias Sociales. CLACSO eBooks,
01/2017
Book Chapter
Table of Contents Gabriela Dutrénit; José Miguel Natera; Martín Puchet Anyul ...
Procesos de diálogo para la formulación de políticas de CTI en América Latina y España,
01/2017
Book Chapter
Front Matter Gabriela Dutrénit; José Miguel Natera; Martín Puchet Anyul ...
Procesos de diálogo para la formulación de políticas de CTI en América Latina y España,
01/2017
Book Chapter