La ville et le territoire sont confrontés, en tant que construits sociaux, à des transformations rapides qui posent la question des mécanismes de résilience, des nouvelles formes d’action et du rôle ...des acteurs, publics ou privés, qui prennent en compte les bouleversements en cours. Ainsi, la créativité et l’innovation se trouvent au cœur de la réflexion urbaine et territoriale. L’ouvrage se structure autour de trois grands champs de réflexion : d’abord celui de l’innovation, de la culture, et de la formation en relation avec le développement territorial ; ensuite l’environnement, vu comme un bien public, notamment grâce à sa gestion, sa protection et la participation citoyenne ; et enfin la gouvernance, la planification et le projet urbain vus à travers le prisme des pratiques, expériences et mobilisations.
The action of a
barbatimão extract on hepatic energy metabolism was investigated using isolated mitochondria and the perfused rat liver. In mitochondria the
barbatimão extract inhibited respiration ...in the presence of ADP and succinate. Stimulation occurred, however, after ADP phosphorylation (state IV respiration). The ADP/O and respiratory control ratios were reduced. The activities of succinate-oxidase, NADH-oxidase and the oxidation of ascorbate were inhibited. The ATPase of intact mitochondria was stimulated, but the ATPases of uncoupled and disrupted mitochondria were inhibited. In perfused livers the extract caused stimulation of oxygen consumption, inhibition of gluconeogenesis and stimulation of glycolysis. Glucose release due to glycogenolysis was stimulated shortly after the introduction of the extract, but inhibition gradually developed as the infusion was continued. Apparently the
barbatimão extract impairs the hepatic energy metabolism by three mechanisms: (1) uncoupling of oxidative phosphorylation, (2) inhibition of mitochondrial electron transport, and (3) inhibition of ATP-synthase.
Full text
Available for:
GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK, ZRSKP
To determine the prevalence of liver changes in workers at an oil refinery located in the state of Bahia, Brazil, as compared to a reference population with no occupational exposure to chemical ...products, and to describe the factors associated with the observed differences in prevalence.
We studied workers at the refinery and at the company's central management office located in the city of Salvador, which is the state capital. Blood samples of 692 refinery workers and 377 workers from the reference population were analyzed. Cases were defined as individuals presenting high serum levels of both gammaglutamyltransferase (GGT) and alanine aminotransferase (ALT) (GGT > 50 U/L for males and > 32 U/L for females; ALT > 50 U/L). Data were collected on age, sex, weight, height, years working for the company, use of alcohol, smoking habits, physical exercise, occupational exposure to chemical products, use of personal safety equipment, and medical history of hepatitis, jaundice, and obesity.
The prevalence of liver changes among refinery workers was 15.3% (95% CI: 12.5 to 18.1), vs. 3.8% (95% CI: 1,8 to 5,8) in the reference population. According to multiple logistic regression analysis, the prevalence of liver changes among refinery workers was 3.56 times greater (95% CI: 1,99 to 6,38) than in the reference population, regardless of the presence of other relevant co-variables, such as obesity, exercise, smoking, and alcohol consumption.
These results suggest that occupational exposure may play a major role in the development of liver changes among workers at the oil refinery where the study was carried out.
State relations / industrial bourgeoisie Pimentel Filho, Geraldo S; Humberto Hauson B de C e Silva; João Miguel C S Castel-Branco ...
Revista de administração pública (Rio de Janeiro),
01/1986, Volume:
20, Issue:
1
Journal Article
Peer reviewed
Open access
The authors try to analyze the relationship between the State and the industrial bourgeoisie, starting from the origins of Brazilian industrialization and reaching up to the SO's. The work is ...presented in four stages and its core is the ineffectuality of the industrial-bourgeois project, especially during periods of crisis and transition. Thus, in the Republica Velha (Old Republic) the beginnings of industrialization are identified as deriving from the trading of coffee and catching up with the Revolutionary Movement of 1930, when it is possible to discern more clearly the bourgeoisie reaching its leading position in society. The concretization of the industrial process and the consolidation of bourgeoisie as a class are stressed in the following stage, from 1930 to 1955. The economic aspects of an internationalization of the economy supported by a State ideology of nationalistic and popular colouring, and also the ensuing political crisis are analysed in the next stage, which cavers the years from 1955 to 1964. The last historical phase intends to be more comprehensive in the analysis of the authoritarian and bureaucratic State emerged in 1964, and this section studies the system of connections created by the industrial bourgeoisie in its dealings with the State, its characteristic ideology, its 1inks with official bureaucracy (viewed here in as an actor in classes dynamics), its behavior during the transitional period of 1974-80 and so on, in terms of the exclusivist, autocratic and dependent developmental model which is a brand of almost this entire phase. The authors end by emphasizing the need of a more effective participation of the citizenry in the process of definition of governmental policies, since such a process, to a great extent, has been defined and implemented by more powerful though less representative sectors of the society, among them the industrial bourgeoisie itself.
Full text
Available for:
CEKLJ, NUK, ODKLJ, UL, UM, UPUK
95.
Brazil under Cardoso Hammond, John L.; Filho, João Roberto Martins
Latin American perspectives,
09/2007, Volume:
34, Issue:
5
Journal Article
Peer reviewed
Full text
Available for:
BFBNIB, INZLJ, NMLJ, NUK, OILJ, PNG, SAZU, UKNU, UL, UM, UPUK, ZRSKP
The harvesting of the sural nerve for autologous grafting usually produces symptoms of low intensity and short duration. In rare occasions that procedure may lead to the formation of a symptomatic ...neuroma in the proximal stump. The symptoms of this complication are usually controlled by clinical treatment and the surgical procedure is left for the therapeutic failures. In this paper we present the case of a patient with a sural nerve neuroma submitted to surgical treatment by a variant of the centro-central anastomosis technique, developed for the treatment of amputation neuromas, that resulted in remission of the painful symptomatology. The different options of surgical treatment for this rare entity are discussed.
OBJETIVO: Identificar aspectos clínico-laboratoriais da endocardite infecciosa valvar, tratada com cirurgia, no Hospital de Messejana, Fortaleza, CE, no período de 1988 a 2003. MÉTODO: Estudo ...observacional, retrospectivo, da fase hospitalar, de 64 pacientes portadores de endocardite infecciosa, submetidos à substituição valvar aórtica e/ou mitral, vegectomia e plastia da tricúspide e excisão da valva pulmonar, como parte do tratamento. Analisados o sexo, a idade, o tempo decorrido entre a internação e a cirurgia e entre a internação e a alta hospitalar, a valva acometida, o resultado da hemocultura, o procedimento cirúrgico efetuado e a mortalidade. RESULTADOS: A endocardite infecciosa valvar, tratada com cirurgia, preponderou na terceira década, 81,2% dos pacientes eram masculinos. O tempo decorrido entre a internamento e a cirurgia foi menor nos pacientes que faleceram. A valva aórtica, de modo isolado ou associado, foi acometida em 65% dos casos. Hemoculturas foram positivas em 42%; em 52,4% delas, isolou-se Estafilolococo aureus. Necessitaram de substituição valvar 93,7% dos pacientes. Houve mortalidade de 14,1%, não influenciada pela idade nem pelo resultado da hemocultura. CONCLUSÃO: Endocardite infecciosa valvar, submetida ao tratamento cirúrgico, foi mais freqüente em homens e na terceira década. Acometeu preferencialmente a valva aórtica. Estafilolococo aureus foi o patógeno mais comum. Na quase totalidade dos casos, procedeu-se substituição valvar e a mortalidade hospitalar foi de 14,1%.
PDF
