Multivariable regression analyses were performed adjusting for demographics, hospital-level characteristics, and relevant comorbidities. Multivariate analysis demonstrated that patients in category ...IV had a significantly higher odds of mortality compared to other BMI subgroups (OR = 1.16, 95% CI: 1.07-1.29, P-value < 0.00). The relationship between extremely low or high BMI values and CDI mortality that has been observed emphasizes the significance of taking BMI into account as a risk factor and potential prognostic indicator in CDI management.
Background Serrated colorectal lesions include hyperplastic polyps (HPs) and sessile serrated adenomas (SSAs). Optical biopsy could misclassify SSAs as unimportant if they resemble HPs. Objective To ...explore the narrow-band imaging (NBI) features of SSAs. We hypothesized that SSAs resemble HPs under NBI. Design Retrospective analysis of data from our prospective study of NBI in routine practice. Setting Single specialty group. Patients Patients undergoing colonoscopy. Intervention Colonoscopy. Main Outcome Measurements Polyp histology prediction by community gastroenterologists. Features of SSAs versus HPs and adenomas by using the Narrow-Band Imaging International Colorectal Endoscopic (NICE) Classification. Results Among 2388 lesions, 141 were diagnosed on pathology as SSAs, 465 as HPs, and 1546 as adenomas. Each individual NICE feature of HPs was found in 38% to 42% of SSAs, 66% to 67% of HPs, and 15% to 20% of adenomas ( P < .001 for each). Each individual NICE feature of adenomas was found in 57% to 62% of SSAs, 33% to 34% of HPs, and 80% to 84% of adenomas ( P < .001 for each). Compared with HPs, SSAs were less likely (odds ratio OR 0.74; 95% confidence interval CI, 0.69-0.79) and adenomas were even less likely (OR 0.62; 95% CI, 0.59-0.64) to have all 3 NICE features of HPs. SSAs >5 mm were more likely than smaller SSAs to have all 3 NICE features of adenomas. SSA location did not predict NBI features. Analyses restricted to high-confidence lesions showed similar results. Limitations The endoscopists were not NBI experts. Conclusion Community gastroenterologists observed a profile of NICE features among SSAs that was intermediate to the profiles observed for HPs and adenomas. These results require confirmation by NBI experts.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
Objective: To analyze the clinical agreement between the conventional intermittent bolus thermodilution (TD) technique and a new arterial pressure waveform analysis (APCO) technique (FloTrac; Edward ...Lifesciences, Irvine, CA) for cardiac output (CO) estimation. Design: Prospective observational clinical study. Setting: Cardiac surgery operating room of a tertiary care cardiac center. Participants: Twelve patients undergoing elective off-pump coronary artery bypass (OPCAB) surgery. Measurements and Main Results: CO was determined by 2 different methods: TD and APCO at 8 time points (preinduction, postinduction, poststernotomy, left internal mammary artery to left anterior descending artery anastomosis, left obtuse marginal/diagonal anastomosis, right right coronary/posterior descending coronary artery anastomosis, postprotamine administration, and poststernal closure) in 12 patients undergoing elective OPCAB surgery. The mean bias and limits of agreement (2 standard deviations) expressed in liters per minute at respective points of measurement were −0.54 ± 1.12, −0.37 ± 1.0, −0.42 ± 1.50, −0.25 ± 1.18, −0.31 + 1.28, ±0.41 ± 1.0, 0.06 ± 1.50, and 0.09 ± 1.40. Conclusion: Good agreement was found between the CO values obtained by the APCO and TD techniques throughout the intraoperative period including the period of coronary artery graft surgery.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
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