There is no consistent association between individual histological lesions and composite scores in donor kidney biopsy and transplant outcomes.
To evaluate which acute or chronic individual ...histological lesions and composite scores in donor kidney were associated with graft survival in the recipient.
We investigated the association of individual histological lesions and 8 composite scoring systems in implantation biopsies of cadaveric (n=101) and living (n=29) kidneys with 5-year death-censored graft survival.
We found a high frequency of chronic lesions in donor kidneys, mostly associated with arteriosclerosis, and less dependent from donor age. Acute, chronic, and total Banff scores for post-transplant biopsies, chronic and total Banff scores for pre-implant biopsies, donor damage score and chronic damage score predicted death-censored graft loss. However, only chronic and total Banff-scores had significant effects in multivariate model. Chronic pre-implant and total post-transplant Banff scores demonstrated the highest area under the curve (AUC) of 0.722 and 0.717, respectively. Among individual lesions, glomerulosclerosis ≥20%, interstitial inflammation >0, arteriosclerosis =3, arteriolar hyalinosis >0, and interstitial fibrosis >0, assessed with Banff-grading criteria, were associated with lower allograft survival. We created the Donor Kidney Damage Index (DKDI), by summing regression coefficients for these lesions, which yielded the AUC of 0.747. When combined with retransplantation, cold ischemia time and acute rejection, DKDI, chronic pre-implant and total post-transplant Banff scores further improved their predictive accuracy, yielding AUCs of 0.842, 0.807, and 0.802, respectively.
DKDI, chronic pre-implant and total post-transplant Banff scores alone and combined with clinical variables may facilitate decision making in post-transplant period.
We demonstrate an unusually strong magneto-optical response of elongated plate-shaped pigment particles in magnetic fields ranging from 0 to 25 T. In a weak field, the particles align perpendicular ...to the field and the dispersions exhibit the Cotton–Mouton effect. In a strong magnetic field, the magneto-optical behaviour is nonlinear and cannot be explained by a simple model of non-interacting diamagnetic rods in a thermal equilibrium. We also demonstrate that the addition of a small amount of magnetic particles results in a complex magneto-optical response, where the particles align parallel to a weak magnetic field and perpendicular to a strong one.
Full text
Available for:
IJS, KILJ, NUK, UL, UM, UPUK
We present results on the effect of extension and compression on liquid crystal filaments formed in the B
7
phase of bent-core mesogens. There are three distinct temperature regimes in which ...substantially different structures may form along the filament. The formation of these structures also depends on the velocity at which the filament is extended or compressed.
Full text
Available for:
BFBNIB, GIS, IJS, KISLJ, NUK, PNG, UL, UM, UPUK
Cross sections for semi-inclusive electroproduction of charged pions (π±) from both proton and deuteron targets were measured for 0.2<x<0.5, 2<Q2<4 GeV2, 0.3<z<1, and Pt2<0.2 GeV2. For Pt<0.1 GeV, we ...find the azimuthal dependence to be small, as expected theoretically. For both π+ and π−, the Pt dependence from the deuteron is found to be slightly weaker than from the proton. In the context of a simple model, this implies that the initial transverse momenta width of d quarks is larger than for u quarks and, contrary to expectations, the transverse momentum width of the favored fragmentation function is larger than the unfavored one.
Full text
Available for:
GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
The article substantiates the problem of forming baby economy as a factor of national economic development in the global environment. The main baby economy evolution directions as a component of the ...nanoeconomic system are formulated in the course of research. In addition, Ukraine’s baby economy subsystem, particularly the practice of growing up, socialization and relationship process, is analysed. It has been revealed how little people in this country can influence the course of economic development. The factor analysis is conducted on baby economy factors’ impact on GDP per capita which determines that our GDP manufacturing does not actively depend on the performance of baby economy. This dependence is 0.57. Therefore, it is necessary to introduce the levers of deploying baby economy processes in Ukraine’s economic environment. Furthermore, it has been estimated that the number of people with higher education is gradually increasing as well as the number of foreign students that results in attractiveness of Ukraine’s higher education. As a result of research, the conclusions are based on the necessity of updating baby economy and the beginning of the national economic system development, taking into account the formation of common approaches to education and upbringing. World experience shows that if the economic behaviour of a child is developed by the appropriate education, the level of national economy adaptation to the global environment becomes a decisive issue.
Quality-control dosimetry is important to the routine operation of a radiation processing facility. For many applications this dosimetry must be traceable to a national primary standard. After ...irradiation at an industrial facility, National Institute of Standards and Technology (NIST)-supplied transfer dosimeters are certified by measurement and dose interpolation from the NIST calibration curve. However, prior to computing the absorbed dose the dosimeter response must be adjusted for the temperature difference between irradiation temperature for the alanine system calibration and the irradiation temperature for the industrial process. For most industrial applications, the temperature is not controlled and varies during the irradiation process. The alanine dosimeter response has a dependence on irradiation temperature, which is compensated for by applying a correction factor to the dosimeter response to compute the absorbed dose. Moreover, there is no consensus protocol to estimate the irradiation temperature and apply this correction. This work approximates industrial temperature profiles using a
60Co source with a temperature-controlled irradiation chamber, and then compares the relative effectiveness of commonly used industrial methods to correct for irradiation temperature influence on the alanine dosimeter response.
Full text
Available for:
GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
Hydrothermal method of temperature difference was employed to determine relationship between growth and dissolution rates on the basal, minor rhombohedral and prism faces of quartz at the same ...absolute values of the temperature gradient, |Δ
T|, and correspondingly the same absolute values of super- and undersaturations, |Δ
C|. The experiments were carried out in 1
m NaOH solution pre-saturated with silica at 1
kbar and (a) 300, 320, 340, 350, 360
°C and |Δ
T|=10
°C; (b) 350
°C and |Δ
T|=10, 15, 20
°C. It was found, that the ratio between absolute values of dissolution and growth rates increased from ∼0.9 to 9.0 on the following quartz faces: basal kinked face of maximum growth rate; minor rhombohedral flat face, having small area and intermediate growth rate; and prism flat face of maximum area and minimum growth rate, thus reflecting enhancement of growth and dissolving asymmetry (the weakest on the kinked face and the highest on the flat one, of maximal area).
Full text
Available for:
GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
Characteristics of high and nano- technologies of global markets are discovered in the article. Exactly conditions of patenting of nano-technologies are defined in the world and in corresponding ...agencies of USA. Factors of publication of nano-articles in international editions and their quantity per million of inhabitants in different countries of the world are outlined. Chief states-producers of nano-knowledges are USA, Japan, Chine and Singapore. Latter is key if the field of expenditure per capita and in a sphere of implementation of data in production. Participation of R&D in increase of GDP is essential for this country. Peculiarity of scientific-technical policy and support of R&D organizations are the factors, which can be used in Ukrainian realities.
PDF
