Strah pred TJ je eden od najbolj vplivnih psiholoških dejavnikov pri učenju TJ in je glede na pomembnost precej slabo raziskan, četudi bi njegovo boljše razumevanje nedvomno pripomoglo k bolj ...prilagojenemu in učinkovitemu učenju TJ. Strah pred TJ se spreminja z govorčevo starostjo in nivojem znanja. Z zbiranjem in analizo 152 vprašalnikov ter s štirimi intervjuji profesoric francoščine kot TJ na dveh slovenskih gimnazijah in na Filozofski fakulteti UL so bili določeni najpogostejši vzroki za pojav strahu pred TJ ter skupino učencev glede na starost in znanje, ki ima z njim največ težav. Rezultati so zelo jasni: pojav je med učenci francoščine v slovenskem šolskem sistemu zelo pogost. Med dijaki prvih letnikov, maturanti, študenti dodiplomskega študija in študenti podiplomskega študija, so se maturanti in študenti dodiplomskega študija izkazali za najbolj problematične. Te ugotovitve spodbujajo razmislek o tem, kako olajšati oz. odpraviti preučevani pojav pri slovenskih učencih francoščine kot TJ.
Sarcopenia is a common skeletal muscle disorder in older people. Here we explore the prevalence of sarcopenia and its impact on men with prostate cancer.
We searched PubMed, Embase, and Web of ...Science databases for relevant studies with an explicit definition of sarcopenia in men with prostate cancer which were published between years 2000 and 2022. Prevalence of sarcopenia and its association with time to biochemical recurrence (BCR), progression-free survival (PFS), non-cancer mortality, overall survival (OS), and treatment-related complications in men with prostate cancer were explored. The summary prevalence, hazard ratios (HRs), and 95% confidence intervals (CIs) were calculated.
A total of 24 studies comprising 3,616 patients with early and advanced prostate cancer were included. The prevalence of sarcopenia and sarcopenic obesity was 43.8% (95% CI 19.2%–68.5%) and 24.0% (95% CI 5.0%–43.1%), respectively. Sarcopenia was not associated with a shorter time to BCR (HR 0.89, 95% CI 0.64–1.23, p = 0.48), a shorter PFS (HR 1.20, 95% CI 0.73–1.97, p = 0.48), or a shorter OS (HR 1.29, 95% CI 0.90–1.85, p = 0.16). In contrast, sarcopenia was significantly associated with a higher non-cancer mortality (HR 1.85, 95% CI 1.23–2.80, p = 0.003). In four out of five studies eligible for assessment, sarcopenia was not associated with an increased risk of treatment-related complications.
Sarcopenia increases the risk of death from other causes in men with prostate cancer. Patients with prostate cancer should be assessed and managed for sarcopenia in everyday clinical practice.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
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Automatic Cell Counter for cell viability estimation Lojk, Jasna; Sajn, Luka; Cibej, Uros ...
2014 37th International Convention on Information and Communication Technology, Electronics and Microelectronics (MIPRO),
05/2014
Conference Proceeding
Despite several methods that exist in different fields of life sciences, certain biotechnological applications still require microscopic analysis of the samples and in many instances, counting of ...cells. Some of those are drug delivery, transfection or analysis of mechanism fluorescent probes are used to detect cell viability, efficiency of a specific drug delivery or some other effect. For analysis and quantification of these results it is necessary to either manually or automatically count and analyze microscope images. However, in everyday use many researchers still count cells manually since existing solutions require either some specific knowledge of computer vision and/or manual fine tuning of various parameters. Here we present a new software solution (named CellCounter) for automatic and semi-automatic cell counting of fluorescent microscopic images. This application is specifically designed for counting fluorescently stained cells. The program enables counting of cell nuclei or cell cytoplasm stained with different fluorescent stained. This simplifies image analysis for several biotechnological applications where fluorescent microscopy is used. We present results and validate the presented automatic cell counting program for cell viability application. We give empirical results showing the efficiency of the proposed solution by comparing manual counts with the results returned by automated counting. We also show how the results can be further improved by combining manual and automated counts.
Automatic adaptation of filter sequences for cell counting Cibej, Uros; Lojk, Jasna; Pavlin, Mojca ...
2015 38th International Convention on Information and Communication Technology, Electronics and Microelectronics (MIPRO)
Conference Proceeding
Manual cell counting in microscopic images is usually tedious, time consuming and prone to human error. Several programs for automatic cell counting have been developed so far, but most of them ...demand some specific knowledge of image analysis and/or manual fine tuning of various parameters. Even if a set of filters is found and fine tuned to the specific application, small changes to the image attributes might make the automatic counter very unreliable. The goal of this article is to present a new application that overcomes this problem by learning the set of parameters for each application, thus making it more robust to changes in the input images. The users must provide only a small representative subset of images and their manual count, and the program offers a set of automatic counters learned from the given input. The user can check the counters and choose the most suitable one. The resulting application (which we call Learn123) is specifically tailored to the practitioners, i.e. even though the typical workflow is more complex, the application is easy to use for non-technical experts.
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