ABSTRACT We find that significant incompleteness in stellar number counts results in a significant overestimate of the microlensing optical depth τ and event rate per star per year Γ toward the ...Galactic bulge from the first two years of the MOA-II survey. We find that the completeness in red clump giant (RCG) counts decreases proportional to the galactic latitude b, as , ranging between 1 and 0.7 at . The previous measurements using all sources by difference image analysis (DIA) by MACHO and MOA-I suffer the same bias. On the other hand, the measurements using an RCG sample by OGLE-II, MACHO, and EROS were free from this bias because they selected only the events associated with the resolved stars. Thus, the incompleteness both in the number of events and stellar number count cancel out. We estimate τ and Γ by correcting this incompleteness. In the central fields with , we find star−1 yr−1 and for the 427 events with days using all sources brighter than mag. Our revised all-source τ measurements are about 2 smaller than the other all-source measurements and are consistent with the RCG measurements within 1 . We conclude that the long-standing problem on discrepancy between the high τ with all-source samples by DIA and low τ with RCG samples can probably be explained by the incompleteness of the stellar number count. A model fit to these measurements predicts star−1 yr−1 at and for sources with , where the future space mission, Wide Field Infrared Space Telescope, will observe.
The Euclid mission is the second M-class mission of the ESA Cosmic Vision programme, with the principal science goal of studying dark energy through observations of weak lensing and baryon acoustic ...oscillations. Euclid is also expected to undertake additional Legacy Science programmes. One such proposal is the Exoplanet Euclid Legacy Survey (ExELS) which will be the first survey able to measure the abundance of exoplanets down to Earth mass for host separations from ∼1 au out to the free-floating (unbound) regime. The cold and free-floating exoplanet regimes represent a crucial discovery space for testing planet formation theories. ExELS will use the gravitational microlensing technique and will detect 1000 microlensing events per month over 1.6 deg2 of the Galactic bulge. We assess how many of these events will have detectable planetary signatures using a detailed multiwavelength microlensing simulator - the Manchester-Besançon microLensing Simulator (MABμLS) - which incorporates the Besançon Galactic model with 3D extinction. MABμLS is the first theoretical simulation of microlensing to treat the effects of point spread function (PSF) blending self-consistently with the underlying Galactic model. We use MABμLS, together with current numerical models for the Euclid PSFs, to explore a number of designs and de-scope options for ExELS, including the exoplanet yield as a function of filter choice and slewing time, and the effect of systematic photometry errors. Using conservative extrapolations of current empirical exoplanet mass functions determined from ground-based microlensing and radial velocity surveys, ExELS can expect to detect a few hundred cold exoplanets around mainly G-, K- and M-type stellar hosts, including ∼45 Earth-mass planets and ∼6 Mars-mass planets for an observing programme totalling 10 months. ExELS will be capable of measuring the cold exoplanet mass function down to Earth mass or below, with orbital separations ranging from ∼1 au out to infinity (i.e. the free-floating regime). Recent ground-based microlensing measurements indicate a significant population of free-floating Jupiters, in which case ExELS will detect hundreds of free-floating planets. ExELS will also be sensitive to hot exoplanets and sub-stellar companions through their transit signatures and this is explored in a companion paper.
Social Symptoms of Parkinson’s Disease Prenger, Margaret T. M.; Madray, Racheal; Van Hedger, Kathryne ...
Parkinson's disease,
12/2020, Volume:
2020
Journal Article
Peer reviewed
Open access
Parkinson’s disease (PD) is typically well recognized by its characteristic motor symptoms (e.g., bradykinesia, rigidity, and tremor). The cognitive symptoms of PD are increasingly being acknowledged ...by clinicians and researchers alike. However, PD also involves a host of emotional and communicative changes which can cause major disruptions to social functioning. These incude problems producing emotional facial expressions (i.e., facial masking) and emotional speech (i.e., dysarthria), as well as difficulties recognizing the verbal and nonverbal emotional cues of others. These social symptoms of PD can result in severe negative social consequences, including stigma, dehumanization, and loneliness, which might affect quality of life to an even greater extent than more well-recognized motor or cognitive symptoms. It is, therefore, imperative that researchers and clinicans become aware of these potential social symptoms and their negative effects, in order to properly investigate and manage the socioemotional aspects of PD. This narrative review provides an examination of the current research surrounding some of the most common social symptoms of PD and their related social consequences and argues that proactively and adequately addressing these issues might improve disease outcomes.
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FZAB, GIS, IJS, IZUM, KILJ, NLZOH, NUK, OILJ, PILJ, PNG, SAZU, SBCE, SBMB, UL, UM, UPUK
Transits and starspots in the WASP-6 planetary system Tregloan-Reed, Jeremy; Southworth, John; Burgdorf, M ...
Monthly Notices of the Royal Astronomical Society,
06/2015, Volume:
450, Issue:
2
Journal Article, Web Resource
Peer reviewed
Open access
We present updates to prism, a photometric transit-starspot model, and gemc, a hybrid optimization code combining MCMC and a genetic algorithm. We then present high-precision photometry of four ...transits in the WASP-6 planetary system, two of which contain a starspot anomaly. All four transits were modelled using prism and gemc, and the physical properties of the system calculated. We find the mass and radius of the host star to be 0.836 ± 0.063 M⊙ and 0.864 ± 0.024 R⊙, respectively. For the planet, we find a mass of 0.485 ± 0.027 M
Jup, a radius of 1.230 ± 0.035 R
Jup and a density of 0.244 ± 0.014 ρJup. These values are consistent with those found in the literature. In the likely hypothesis that the two spot anomalies are caused by the same starspot or starspot complex, we measure the stars rotation period and velocity to be 23.80 ± 0.15 d and 1.78 ± 0.20 km s−1, respectively, at a colatitude of 75.8°. We find that the sky-projected angle between the stellar spin axis and the planetary orbital axis is λ = 7.2° ± 3.7°, indicating axial alignment. Our results are consistent with and more precise than published spectroscopic measurements of the Rossiter–McLaughlin effect. These results suggest that WASP-6 b formed at a much greater distance from its host star and suffered orbital decay through tidal interactions with the protoplanetary disc.
ABSTRACT
We present the first short-duration candidate microlensing events from the Kepler K2 mission. From late April to early July 2016, Campaign 9 of K2 obtained high temporal cadence observations ...over a 3.7 deg2 region of the Galactic bulge. Its primary objectives were to look for evidence of a free-floating planet (FFP) population using microlensing, and demonstrate the feasibility of space-based planetary microlensing surveys. Though Kepler K2 is far from optimal for microlensing, the recently developed mcpm photometric pipeline enables us to identify and model microlensing events. We describe our blind event-selection pipeline in detail and use it to recover 22 short-duration events with effective time-scales teff < 10 d previously announced by the OGLE and KMTNet ground-based surveys. We also announce five new candidate events. One of these is a caustic-crossing binary event, modelled in a companion study. The other four have very short durations (teff < 0.1 d) typical of an Earth-mass FFP population. Whilst Kepler was not designed for crowded-field photometry, the K2C9 data set clearly demonstrates the feasibility of conducting blind space-based microlensing surveys towards the Galactic bulge.
We report the discovery of a giant planet in event UKIRT-2017-BLG-001, detected by the United Kingdom Infrared Telescope (UKIRT) microlensing survey. The mass ratio between the planet and its host is ..., about 1.5 times the Jupiter/Sun mass ratio. The event lies 0 35 from the Galactic center and suffers from high extinction of AK = 1.68. Therefore, it could be detected only by a near-infrared (NIR) survey. The field also suffers from large spatial differential extinction, which makes it difficult to estimate the source properties required to derive the angular Einstein radius. Nevertheless, we find evidence suggesting that the source is located in the far disk. If correct, this would be the first source star of a microlensing event to be identified as belonging to the far disk. We estimate the lens mass and distance using a Bayesian analysis to find that the planet's mass is , and it orbits a star at an instantaneous projected separation of au. The system is at a distance of kpc, and so likely resides in the Galactic bulge. In addition, we find a non-standard extinction curve in this field, in agreement with previous results toward high-extinction fields near the Galactic center.
Depression is the leading cause of disability worldwide and its effects can be fatal, with over 800,000 people dying by suicide each year. Neuromodulatory treatments such as transcranial magnetic ...stimulation (TMS) are being used to treat depression. Despite its endorsement by two regulatory bodies: NICE (2016) and the FDA (2008), there are major questions about the treatment efficacy and biological mechanisms of TMS. Ahn et al.’s (2013) justified the use of TMS in a clinical context in an important study indicating that excitatory TMS increases reward responsiveness. A pseudo-replication of this study by Duprat et al., (2016) also found a similar effect of active TMS, but only with the addition of an exploratory covariate to the analyses–trait reward responsiveness. Here we replicate Ahn et al.’s (2013) key study, and to test the reliability of the effects, and their dependency on trait reward responsiveness as described by Duprat et al., (2016). Using excitatory and sham TMS, we tested volunteers using the probabilistic learning task to measure their reward responsiveness both before and after stimulation. We also examined affect (positive, negative) following stimulation. Irrespective of TMS, the task was shown to be sensitive to reward responsiveness. However, we did not show TMS to be effective in increasing reward responsiveness and we did not replicate Ahn et al., (2013) or Duprat et al., (2016)'s key findings for TMS efficacy, where we provide evidence favouring the null. Moreover, exploratory analyses suggested following active stimulation, positive affect was reduced. Given our findings, we question the basic effects, which support the use of TMS for depression, particularly considering potential deleterious effects of reduced positive affect in patients with depression.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
Extensive motor skill training induces reorganization of movement representations and synaptogenesis within adult motor cortex. Motor skill does not, however, develop uniformly across training ...sessions. It is characterized by an initial fast phase, followed by a later slow phase of learning. How cortical plasticity emerges during these phases is unknown. Here, we examine motor map topography and synapse number within rat motor cortex during the early and late phases of motor learning. Adult rats were placed in either a skilled or unskilled reaching condition (SRC and URC, respectively) for 3, 7, or 10 d. Intracortical microstimulation of layer V was used to determine the topography of forelimb movement representations within caudal forelimb area of motor cortex contralateral to the trained paw. Quantitative electron microscopy was used to measure the number of synapses per neuron within layer V. SRC animals showed significant increases in reaching accuracy after 3, 7, and 10 d of training. In comparison with URC animals, SRC animals had significantly larger distal forelimb representations after 10 d of training only. Furthermore, SRC animals had significantly more synapses per neuron than URC animals after 7 and 10 d of training. These results show that both motor map reorganization and synapse formation occur during the late phase of skill learning. Furthermore, synaptogenesis precedes map reorganization. We propose that motor map reorganization and synapse formation do not contribute to the initial acquisition of motor skills but represent the consolidation of motor skill that occurs during late stages of training.
We report the analysis of additional multiband photometry and spectroscopy and new adaptive optics (AO) imaging of the nearby planetary microlensing event TCP J05074264+2447555 (Kojima-1), which was ...discovered toward the Galactic anticenter in 2017 (Nucita et al.). We confirm the planetary nature of the light-curve anomaly around the peak while finding no additional planetary feature in this event. We also confirm the presence of apparent blending flux and the absence of significant parallax signal reported in the literature. The AO image reveals no contaminating sources, making it most likely that the blending flux comes from the lens star. The measured multiband lens flux, combined with a constraint from the microlensing model, allows us to narrow down the previously unresolved mass and distance of the lens system. We find that the primary lens is a dwarf on the K/M boundary (0.581 0.033 M ) located at 505 47 pc, and the companion (Kojima-1Lb) is a Neptune-mass planet (20.0 2.0 M⊕) with a semimajor axis of au. This orbit is a few times smaller than those of typical microlensing planets and is comparable to the snow-line location at young ages. We calculate that the a priori detection probability of Kojima-1Lb is only ∼35%, which may imply that Neptunes are common around the snow line, as recently suggested by the transit and radial velocity techniques. The host star is the brightest among the microlensing planetary systems (Ks = 13.7), offering a great opportunity to spectroscopically characterize this system, even with current facilities.
Difficulty with emotion recognition is increasingly being recognized as a symptom of Parkinson’s disease. Most research into this area contends that progressive cognitive decline accompanying the ...disease is to be blamed. However, facial mimicry (i.e., the involuntary congruent activation of facial expression muscles upon viewing a particular facial expression) might also play a role and has been relatively understudied in this clinical population. In healthy participants, facial mimicry has been shown to improve recognition of observed emotions, a phenomenon described by embodied simulation theory. Due to motor disturbances, Parkinson’s disease patients frequently show reduced emotional expressiveness, which translates into reduced mimicry. Therefore, it is likely that facial mimicry problems in Parkinson’s disease contribute at least partly to the emotional recognition deficits that these patients experience and might greatly influence their social cognition abilities and quality of life. The present review aims to highlight the need for further inquiry into the motor mechanisms behind emotional recognition in Parkinson’s disease by synthesizing behavioural, physiological, and neuroanatomical evidence.
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FZAB, GIS, IJS, IZUM, KILJ, NLZOH, NUK, OILJ, PILJ, PNG, SAZU, SBCE, SBMB, UL, UM, UPUK