Ulcerative colitis (UC) is an inflammatory disease that affects the colon and rectum. Recently, evidence has emerged about the influence of microbiota on the development of this disease. However, ...studies on the role of intestinal microbiota in the pathogenesis of UC have been incomplete. In addition, there are no comprehensive studies of the causes of ulcerative colitis and data on the microbiological composition of the intestines of patients with ulcerative colitis in Russia. We carried out a study of the microbiological composition of the intestines of patients with ulcerative colitis and healthy individuals. We found significant changes in the bacteria genera and species in patients with UC compared with the control group using sequencing on the IonTorrent PGM system and subsequent data analysis. In our study we observed a significant increase of the genus Haemophilus, Olsenella, Prevotella, Cedecea, Peptostreptococcus, Faecalibacterium, Lachnospira, Negativibacillus, Butyrivibrio, and the species Bacteroides coprocola, Phascolarctobacterium succinatutens, Dialister succinatiphilus, Sutterella wadsworthensis, Faecalibacterium prausnitzii in patients with ulcerative colitis. In addition, in patients with ulcerative colitis there was a significant decrease in the genus Fusicatenibacter, Butyricimonas, Lactococcus, Eisenbergiella, Coprobacter, Cutibacterium, Falsochrobactrum, Brevundimonas, Yersinia, Leuconostoc and in the species Fusicatenibacter saccharivorans. We found confirmation of our data with literary sources and studies of UC. In addition, we discovered a few taxa such as Negativibacillus spp. and Falsochrobactrum spp. that have not been previously found in human stool samples. Our data confirm that more research is needed to understand the role of microbiome changes in the development of UC in different people populations.
Intestinal microbiota, ulcerative colitis, inflammatory bowel disease, sequencing, Russian population.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
Abstract
In this article, we discuss a new software package of
kinematic and vertex fitting for the CMD-3 experiment at
the VEPP-2000 electron-positron collider. The authors describe in
detail the ...fitting algorithm, parametrization of four-momenta and
trajectories of various particles and present the results of testing
the fitting pakage using events of Monte Carlo simulation of various
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annihilation processes. The authors also provide several
examples of the fitting package validation using Gaussian
simulation. Although the package discussed in this article is
intended for the CMD-3 experiment, it can also be used in
other experiments. The authors consider the described package as
their first step towards a more universal and rigorous kinematic and
vertex fitting package that can be used in future
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experiments, such as the Super Charm-Tau factory.
A
bstract
In this paper, we propose a new method for obtaining a Born cross section using visible cross section data. It is assumed that the initial state radiation is taken into account in a visible ...cross section, while in a Born cross section this effect is ommited. Since the equation that connects Born and visible cross sections is an integral equation of the first kind, the problem of finding its numerical solution is ill-posed. Various regularization-based approaches are often used to solve ill-posed problems, since direct methods usually do not lead to an acceptable result. However, in this paper it is shown that a direct method can be successfully used to numerically solve the considered equation under the condition of a small beam energy spread and uncertainty. This naive method is based on finding a numerical solution to the integral equation by reducing it to a system of linear equations. The naive method works well because the kernel of the integral operator is a rapidly decreasing function of the variable
x
. This property of the kernel leads to the fact that the condition number of the matrix of the system of linear equations is of the order of unity, which makes it possible to neglect the ill-posedness of the problem when the above condition is satisfied. The advantages of the naive method are its model independence and the possibility of obtaining the covariance matrix of a Born cross section in a simple way.
It should be noted that there are already a number of methods for obtaining a Born cross section using visible cross section data, which are commonly used in
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experiments. However, at least some of these methods have various disadvantages, such as model dependence and relative complexity of obtaining a Born cross section covariance matrix. It should be noted that this paper focuses on the naive method, while conventional methods are hardly covered. The paper also discusses solving the problem using the Tikhonov regularization, so that the reader can better understand the difference between regularized and non-regularized solutions. However, it should be noted that, in contrast to the naive method, regularization methods can hardly be used for precise obtaining of a Born cross section. The reason is that the regularized solution is biased and the covariance matrix of this solution do not represent the correct covariance matrix of a Born cross section.
•We showed how the magnetic field of non-uniform waveguide influences for 3D crystals.•Explored conditions for forward and backward spin waves existence in meander profile.•Comparison dispersion ...patterns for surface and bulk modes in 3D magnonic crystal.
We present three-dimensional (3D) model of periodic meander-shaped ferromagnetic films. Spin wave propagation in such films and vertically coupled structures was studied using micromagnetic modeling and theoretical plane wave method. Spin waves in these structures essentially propagate in film’s segments located at right angles with respect to each other. This makes really possible for the wave to propagate in three dimensions. We calculated internal effective magnetic fields and obtained spin wave dispersion in single and vertically coupled structures. Additionally, comparison of surface and volume spin waves propagation in such meander films was provided. Our results can be useful for magnonic logic elements development.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
Streamer-to-filament transition is a general feature of nanosecond discharges at elevated pressure. The transition is observed in different discharges by different groups: in the nanosecond surface ...dielectric barrier discharges (nSDBDs) in a single shot regime at high pressure (2-15 bar), in the point-to-point or point-to-plane open electrodes discharges at high repetitive frequency (so-called nanosecond repetitive pulsed discharges, NRPDs) at atmospherics pressure. The present paper contains experimental analysis of plasma properties in the filamentary nSDBD: the electrical current, the specific deposited energy, the electron density and the electron temperature were measured for a wide range of pressures and voltages. A model explaining plasma properties in filamentary nanosecond discharges and the role of excited species in streamer-to-filament transition is suggested and discussed.
A process of searching on the sphere for the best (in a sense) cubature formulas that are invariant under the transformations of the icosahedral rotation group is described. The parameters of the ...best cubature formulas of this symmetry type up to the 30th order of accuracy are given to 16 significant digits. A table which contains the main characteristics of all the best to date cubature formulas of the icosahedral rotation group up to the 79th order of accuracy is given.
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EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
Graphene is a one-atom-thick planar sheet of a honeycomb carbon crystal. Its gapless and linear energy spectra of electrons and holes lead to nontrivial features such as giant carrier mobility and ...broadband flat optical response. In this paper, recent advances in graphene-based devices in terahertz science and technology are reviewed. First, the fundamental basis of the optoelectronic properties of graphene is introduced. Second, synthesis and crystallographic characterization of graphene material are described, particularly focused on the authors' original heteroepitaxial graphene-on-silicon technology. Third, nonequilibrium carrier relaxation and recombination dynamics in optically or electrically pumped graphene are described to introduce a possibility of negative-dynamic conductivity in a wide terahertz range. Fourth, recent theoretical advances towards the creation of current-injection graphene terahertz lasers are described. Fifth, the unique terahertz dynamics of the two-dimensional plasmons in graphene are described. Finally, the advantages of graphene devices for terahertz applications are summarized.
Herein we report the study of the influence of synthesis conditions during the microwave-hydrothermal crystallization of freshly precipitated gels on the phase composition and morphology of the ...rare-earth doped yttrium orthophosphates nanoparticles. We characterize the nanoparticles of YPO sub(4) and YPO sub(4) times 0.8H sub(2)O using X-ray diffraction analysis, TEM, and FT-IR spectroscopy. Furthermore, we argue that for the given phase the degree of crystallinity and thus the sample morphology depend strongly on the synthesis conditions. We establish that the hexagonal hydrate phase can be obtained by means of microwave-hydrothermal method if one uses phosphate anion excess or adjusts pH of the reaction mixture. Also we show that the metastable hydrate phase is most likely stabilized by hydroxyl groups at elevated temperatures.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
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