Abstract
The aim of the study was the detection of TRP, kynurenine (KYN), and kynurenic acid (KYNA) in human sweat, and determining whether physical activity affects their content in this secrete. ...Two different methods were used simultaneously—collection of sweat by means of an absorption pad from the inter scapular region, and collection of a drop of sweat from the region of the forehead. Quantitative determinations of TRP, KYN and KYNA were performed using high performance liquid chromatography with ultraviolet and fluorescence detection. Determinations of sodium was carried out by the method of inductively coupled plasma collision/reaction cell ionization mass spectrophotometry. It was found that physical exercises evoked a decrease in the amount of KYN, and an increase in the amount of KYNA in sweat recorded on day 14, but not on day 28 of training. It appears that physical exercises result in a long-term increase in the kynurenine transaminase activity responsible for the formation of KYNA from KYN. Based on this results, it can be suggested that measurement of TRP, KYN and KYNA in sweat may have diagnostic potential and may help to establish an exercise regime appropriate for the age, gender and health status of rehabilitation patients.
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IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
The answer to current social and health needs of people aged over 60 are the multidirectional and carefully planned, comprehensive activation and rehabilitation activities carried out as part of ...Daycare Centres (DCC). The aim of creating and the functioning of DCCs deployed all over Poland is to improve the health and psychophysical fitness of this group of people. Health factors and psychophysical fitness determine the ability to live independently, both today, and later in life.
The objective of the study was to assess the impact of comprehensive ambulatory rehabilitation, including tailored endurance training preceded by an ergospirometry test, on indicators demonstrating the ability to live independently and the risk ratio of future health problems in the elderly.
60 people participating in a rehabilitation cycle implemented as part of the services provided to patients aged over 60 in the DCC of the Witold Chodźko Institute of Rural Medicine (IMW) in Lublin comprised the sample. The tests were carried out in the test-retest model on the first and last day of the kinesiotherapy cycle. Patients were tested using standardized Barthel, I-ADL and VES-13 questionnaires. The rehabilitation programme applied included systemic kinesiotherapy (endurance training) with a load determined according to individual exercise capacity, determined on the basis of a ergospirometry test, and varied rehabilitation activities resulting from the condition of the locomotor system, as provided for under the project.
After completing the rehabilitation cycle, patients obtained higher results in comparison to the tests carried out before the beginning of the cycle in the Barthel index used to measure functional efficiency (Z = 5.41; p = 0.001), as well as lower in the I-ADL scale used to test the degree of dependence on the help of others when performing complex activities of everyday life (Z = 2.63; p = 0.009) and in VES-13 scale used to assess the risk of geriatric health problems (Z = 5.47; p = 0.001).
As the result of the use of comprehensive rehabilitation, including obligatory endurance training, desired changes were achieved in terms of fitness and independence in performing advanced daily activities and reducing the risk of geriatric health problems.
Systematic, dynamic physical effort brings about tremendous health benefits, not only in young individuals, but as a form of primary prevention, and primarily as secondary prevention of ...cardiovascular system diseases.
The research project was conducted in the Rehabilitation Centre at the Witold Chodźko Institute of Rural Health (IMW) in Lublin, Poland, and covered a group of 927 ambulatory patients. From among the study group, two subgroups were distinguished (Groups 1 and 2). Selection of patients was targeted, based on the criterion of the existing diagnosis of cardiovascular diseases (Group 1; N=53), and the lack of these diseases (Group 2; N=53). The daily level of physical activity was assessed using the monitoring application (Instrument for Activity Measurement IMW) - using a short version of the International Physical Activity Questionnaire (IPAQ), and alternatively analyzing the data from a smartphone accelerometer.
The total level of weekly physical activity in Group 1 was 4532.88±3611.6 MET-min/week, and was considerably higher, compared to the control group (3142.58±2536.9 MET-min/week). Also, the values of weekly caloric cost of physical activity (KAF kcalxweek
) showed higher values (6935.77±5957.4), compared to the control group (4274±3344.9). The group of cardiologic patients (Group 1) showed a higher level of activity, especially within the range of effort on an intensive level, and low level - going for walks, walking(MET1, MET3), which was also translated into the caloric cost of these levels of physical activity (KAF1, KAF3).
The results of the study indicated a significantly higher level of physical activity in the group of patients with concomitant cardiovascular diseases, compared to the control group. The overestimation of the level of physical activity perceived by patients seems to be an important problem, especially in the control group.
One possible way of iron loss is sweating. It is unclear how physical activity performed by untrained individuals affects the iron status in sweat.
The purpose of this study was to analyse iron ...concentration in sweat during 4-week exercise training to determine the changes in iron excretion during follow-up exercises.
43 untrained volunteers participated in the study, 29 of whom completed the full exercise programme. The training programme consisted of exercises on a cycle ergometer and cross-trainer. In the first week, participants exercised for 8 minutes on each device, in the second for 10 minutes, and in the third and fourth weeks they exercised for 15 min on each device. Intensity was submaximal and defined as 85% of maximal heart rate. A sterile sweat patch was placed on the skin between shoulder blades.
Concentration of iron on the first and the fifteenth day of exercises was comparable and statistically insignificant. Iron concentration was highly increased on the last day of training in comparison with first (p<0.001) and fourteenth day (p<0.006). The median of iron concentration in 29 samples on the first day of sampling was 21.2 ppb, in the fifteenth - 52.5 ppb, and on the twenty-eighth day - 286.2 ppb. In relation with the sodium concentration, the iron content was also increased on the twenty-eighth day of the training programme (p<0.005).
Iron sweat loss significantly increased during the 4-week exercise programme. A possible explanation may be improvement in the thermoregulation mechanism and secretory activity of sweat glands. Iron sweat loss may be an indicator of iron deficiency observed in active individuals.
Depressive disorders are one of the most common psychiatric disorders. Recognition of signs of mental health disorders is not always easy, hence the availability of simple and accurate tools for ...assessing them is very important in the practice of primary care.
The aim of the study is to assess the theoretical accuracy and reliability of the Patient Health Questionnaire-9 (PHQ-9) in Polish conditions, when applied to general population studies for adults aged between 35-64.
The study comprised a population of 4,040 people. Women constituted 59% of the research population and people living in the countryside 65%. The average age of participants was 53.45 ± 7.05 years. According to PHQ-9, 727 people (18.0%) had moderate, moderate to severe or severe depression. PHQ-9 showed a significant positive internal cohesion (Cronbach's alpha = 0.77), and factor charges oscillated between 0.43-0.63, and the R
coefficients of determination were in the range of 0.21-0.40.
The Polish version of PHQ-9 is a valid tool for diagnosing depression in the general population aged 35-64. Good psychometric properties and compactness make the PHQ-9 a useful clinical and research tool.
The Scale for Evaluating Attitudes towards Seniors (SEAS) was developed based on the concept of social attitudes towards the elderly by G. Miałkowska. The main objective of the study was validation ...of Scale.
The validation procedure was carried out on a sample of 304 adults. Content validity was estimated based on the CVR coefficient, the theoretical validity was verified by means of exploratory factor analysis with simple Oblimin rotation and Kaiser normalization, and criterion validity determined based on analysis of the correlation matrix of SEAS from IVE and SES. Reliability of the tool was estimated based on the values of alpha Cronbach and the discriminatory power of test items coefficients.
Content validity rates CVR range from 0.83-1.00. Three SEAS factors were distinguished on the basis of factor analysis - Respect and Support, Rejection and Misunderstanding, Social distance. Their alpha Cronbach's coefficient range is 0.93-0.86. Extracted SEAS scales correlate with IVE and SES dimensions.
The validation procedure confirms the high psychometric properties of the constructed research tool and allows its use in both individual diagnosis and scientific research, which in turn will contribute to broadening of knowledge about the psychological mechanisms associated with seniors' perception, and can be used to design responses to preventive actions supporting quality of intergenerational interpersonal interactions.
Introduction and objective: An important role in the pathogenesis of asthma in children is played by individual parameters and environmental factors, in particular, those related to the place of ...residence. The aim of this study was to assess the impact of the living environment on the basic demographic and clinical parameters of preschool children with IgE-dependent asthma. Material and methods: 176 children (126 from urban and 52 from rural areas) aged 5.22±0.34 years, with newly-diagnosed IgE-dependent asthma, hospitalised at the Clinic for Lung Diseases and Paediatric Rheumatology of the Prof. Antoni Gębala Children’s Hospital of Lublin, were qualified for the study. Medical documentation of the children was analysed, including the implementation of vaccinations. Due to the clinical form of the disease, patients were separated into groups with mild, moderate and severe asthma. Results: No statistically significant differentiation was observed between age and current body weight and height of the children. Similarly, gender and the clinical form of asthma were not significantly correlated with the place of residence. Children with asthma, at the time of exacerbation symptoms of the disease, living in a city, significantly more often (p <0.05) were treated with antibiotics in the hospital during hospitalization, while the value of OR (5.08) indicated that the rural environment enforces more frequent use of OGCs during asthma exacerbation therapy. In children from the urban environment, there was a significant correlation between the current body weight and serum calcium concentration, as well as a negative statistically significant correlation between the current body weight and serum selenium concentration. Conclusions: Residence does not determine the clinical course of IgE-dependent asthma in preschool children.
The way of functioning in everyday life and the style of coping with the challenges encountered, including the situations of financial difficulties, are shaped by various adaptation mechanisms ...conditioned by the state of psychophysical health, as well as social and cultural factors. They are related to the intrapsychic features, among which the personality plays a key role.
The research sample consisted of 2 groups - 50 patients with mobility impairment resulting from chronic pathologies of the locomotor system hospitalized in the Department of General and Neuro Rehabilitation, Institute of Rural Health in Lublin, and 50 healthy people. The research was carried out using the NEO-FFI Personality Inventory, Perceived Stress Scale, Self-Esteem Scale, General Self-Efficacy Scale, Impulsiveness Inventory and the APSZ Questionnaire.
In the group of patients with impaired mobility resulting from chronic pathologies of the locomotor system, the leading correlate of the tendency to seek help in the situation of indebtedness was extraversion. In the healthy group, the leading correlates of the tendency to undertake this type of activity were the intensity of perceived stress, neuroticism, self-esteem, self- efficacy and empathy.
In the group of patients with impaired mobility resulting from chronic diseases of the locomotor system, extroversion was the factor conducive to seeking help in the situation of indebtedness. In the group of healthy people, self-esteem, self- efficacy and empathy were the factors conducive to taking such actions, whereas intensity of perceived stress and neuroticism were the risk factors.
Cessation of tobacco use has the potential to provide the greatest immediate benefits for tobacco control. Understanding the social determinants of smoking cessation is an essential requirement for ...increasing smoking cessation at the population level. The purpose of this study was to analyze the socio-economic dimensions associated with cessation success among adults in Argentina and Uruguay.
Data from the Global Adult Tobacco Survey (GATS), a cross-sectional, population-based, nationally representative survey conducted in Argentina (n=5,383) and Uruguay (n=4,833) was utilized. Univariable and multivariable logistic regression analyses with results being presented as odds ratios (OR) with 95% confidence intervals were applied to study differences among those respondents who sustained smoking abstinence (≥1 year) and those who continued smoking.
The GATS study revealed that social gradients in tobacco quitting exist in Argentina and Uruguay. Being aged 25-34, particularly men in Uruguay, women in Argentina, low educated men in Argentina and having a lower asset index were associated with reduced odds for quitting.
Factors that are driving differences in smoking cessation between diverse social groups in Latin America countries need to be considered when implementing relevant interventions to ensure tobacco control strategies work effectively for all population segments.
Postmenopausal women working in agriculture suffer from spinal pain for two overlapping reasons, the first is related to the menopause and the second to the specificity of rural work, which includes ...lifting heavy objects and changing weather conditions. Spinal pain affects the daily life of women as well as their ability to work. The objective of the study was to analyse the impact of spinal pain on activities of daily life in Polish postmenopausal women performing agricultural work.
The study was conducted in 2016 in Poland and included 1,119 post-menopausal women living in rural areas and working in agriculture. The women assessed the severity of spinal pain in 3 sections: neck, thorax and lumbar. Neck Disability Index (NDI) and Oswestry Low Back Disability Index (ODI) questionnaires were used to assess the impact of spinal pain on daily life activities. Generalized linear models were estimated in statistical analyses.
Postmenopausal women working in agriculture suffered most often from pain in the lumbar spine, less frequently in the neck, and the least in the thoracic. The most common was an isolated pain in only one section of the spine. Spinal pain disturbed the most the women's rest, standing, lifting objects, while sleep, concentration, and walking the least. The impact of spinal pain on the activities of daily life, on average, was moderate, and increased with greater pain severity, the earlier the age the pain started, the higher the body weight, the lower education level and if there was a co-existing pain in any of the other spine sections. The impact of spinal pain on daily life activities did not depend on age between 45-65, WHR, age at last menstruation, parity, and number and types of births.
The impact of spinal pain on daily life activities in postmenopausal women working in agriculture was assessed as moderate, on average, and depended mainly on spinal pain-related characteristics, such as severity, age at onset and co-existence of pain in any other spinal sections.
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