The purpose of this study was to examine the effects of combining specific adhesive materials and various surface treatments on bonding durability and microleakage of vertically fractured roots. ...Adhesive models were prepared using bovine lower incisors. The experiment included the following five groups: SB-G group (control) (10% citric acid with 3% ferric chloride solution (10-3 solution) + an adhesive resin cement (4-META/MMA-TBB; Super-Bond
)), EC group (self-cure bonding agent (UB) + core composite resin (EC)), EC-G group (10-3 solution + UB + EC), EC-P group (40% phosphate solution + UB + EC), and EC-E group (18% ethylenediaminetetraacetic acid (EDTA) solution + UB + EC). After applying a load of 50,000 cycles, microleakage, microtensile bond strength (μTBS), and failure modes were examined. Microleakage of the EC, EC-G, and EC-E groups was significantly lower than that of the EC-P group. The μTBS of the EC-G group was significantly higher than that of the other groups. All EC groups showed that mixed (cohesive and adhesive) and adhesive failures were the most prevalent types of failure modes. The EC-G group showed the highest bonding durability and the lowest microleakage results, which indicates a possible alternative to current adhesive and tooth surface treatments.
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IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
Objective We aimed to examine the effects of isometric handgrip (IHG) training on home blood pressure (BP) levels in hypertensive Japanese patients undergoing treatment. Methods Fifty-three ...hypertensive patients (mean age, 61.7 years; 56.6% men) with a home systolic BP ≥135 mmHg and/or a home diastolic BP ≥85 mmHg were randomly assigned to either group A or B. As per the crossover design, group A performed 8 weeks of IHG training, followed by an equivalent training-free, control period, while the reverse protocol was performed by group B. The baseline characteristics were similar between both groups. The individualized daily IHG training comprised four sets of 2-min isometric contractions at 30% of the individual's maximum voluntary contraction capacity, including 1 min of rest between sets, for ≥3 days/week. The outcome measure was morning and evening home BP readings taken over the last 2 weeks of the training and control periods. Results A combined data analysis for both groups showed that IHG training was significantly associated with the lowering of both systolic and diastolic BP in the morning (137.9±9.3 vs. 135.3±9.5 mmHg, p=0.007 and 83.0±9.5 vs. 81.2±9.3 mmHg, p<0.001, respectively) and evening (130.0±10.7 vs. 127.6±10.1 mmHg, p=0.003 and 75.8±10.4 vs. 73.8±9.2 mmHg, p<0.001, respectively), while no significant change was observed after the control period. A larger increase in the maximum grip strength due to IHG training was associated with greater BP reductions. Conclusion An 8-week period of IHG training significantly lowered both the morning and evening home BP in hypertensive Japanese patients undergoing treatment.
Introduction: Predictive biomarkers for the therapeutic outcome of induction therapy with systemic corticosteroid for active ulcerative colitis (UC) have not been established. This study aimed to ...investigate whether neutrophil-to-lymphocyte ratio (NLR) and/or platelet-to-lymphocyte ratio (PLR) can be predictive biomarkers for the therapeutic outcomes of systemic corticosteroid therapy in UC. Methods: This was a single-center retrospective cohort study. In total, 48 patients with UC who received induction therapy with systemic corticosteroid were enrolled. Based on the achievement of clinical remission after 8 weeks of treatment, the patients were divided into the remission group (n = 28) and the nonremission group (n = 20). Clinical characteristics, NLR, and PLR at baseline between the remission and nonremission groups were compared via a univariate analysis. The independent risk factors of nonremission were identified via a multivariate analysis. Results: The baseline Mayo score, platelet count, lymphocyte count, C-reactive protein (CRP) levels, NLR, and PLR between the 2 groups significantly differed. The nonremission group had higher NLR and PLR than the remission group (4.70 3.04–11.3 vs. 3.10 1.36–16.42; p < 0.05, and 353.6 220.3–499.8 vs. 207.2 174.4–243.6; p < 0.001, respectively). A multivariate analysis revealed that a Mayo score of ≥9, CRP level of ≥1.26 mg/dL, and PLR of ≥262 (hazard ratio: 23.1, 95% confidence interval: 1.29–413.7, p = 0.033) were considered independent risk factors for nonremission. Conclusion: This report first identified the efficacy of NLR and PLR as candidate biomarkers for predicting the therapeutic outcomes of systemic corticosteroid therapy in UC.
Solitary Peutz–Jeghers polyp is a rare hamartomatous polyp that has similar histologic characteristics with those of polyps in Peutz–Jeghers syndrome, without associated mucocutaneous ...hyperpigmentation and a family history. Previous reports indicated that solitary Peutz–Jeghers polyp is rarely found in the small intestine. We experienced a rare case of jejunal solitary Peutz–Jeghers polyp. A 29-year-old man was admitted to our hospital with a 6-month history of upper abdominal pain. He had no hyperpigmentation or a family history of Peutz–Jeghers syndrome. Abdominal computed tomography showed a 3-cm tumor-like structure at the tip of a mildly intussuscepted jejunum. Per oral double-balloon enteroscopy revealed a 3-cm pedunculated polyp in the jejunum. The patient underwent partial jejunal resection under laparotomy. Macroscopically, the surgical specimen showed a pedunculated polyp, measuring 30 × 15 × 10 mm in size, with lobulated head. Histopathologic examination revealed irregular aggregation of hyperplastic crypts with branching muscular bundles originating from the muscularis mucosae. Based on these histologic findings, we finally diagnosed the patient as a solitary Peutz–Jeghers polyp in the jejunum. The present case indicated that solitary Peutz–Jeghers polyp should be considered in a patient with solitary hamartomatous polyp in the gastrointestinal tract.
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EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OBVAL, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
Radiolysis calculations of simulated seawater were conducted using reported data on chemical yields and chemical reaction sets to predict the effects of seawater constituents on water radiolysis. ...Hydrogen, oxygen, and hydrogen peroxide were continuously produced from simulated seawater during γ-ray irradiation. The concentration of H
2
exceeded its saturation concentration before it reached the steady-state concentration. The production behavior of these molecules was significantly promoted by the addition of bromide ions (Br
−
) because of the high reactivity of Br
−
with the hydroxyl radical, an effective hydrogen scavenger. It is also shown that the concentrations of these molecules were effectively suppressed by diluting seawater constituents by less than 1%.
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BFBNIB, GIS, IJS, KISLJ, NUK, PNG, UL, UM, UPUK
Multiple myeloma is a type of plasma cell neoplasm that produces monoclonal immunoglobulin. Multiple myeloma is known to cause immunoglobulin light-chain (AL) amyloidosis, which frequently involves ...the kidney and heart. Bone pain or fractures caused by osteolytic lesions and physical disorders related to renal or cardiac AL amyloidosis are major initial symptoms in multiple myeloma. Multiple myeloma diagnosed from the gastrointestinal symptoms is rare. We report a case of an 80-year-old man with multiple myeloma accompanied by gastrointestinal AL amyloidosis and secondary protein-losing enteropathy. The diagnostic process was suggestive, in that diarrhea and refractory leg edema related to protein-losing enteropathy were the primary symptoms and the trigger for making a sequential diagnosis of gastrointestinal AL amyloidosis and underlying multiple myeloma. This case is highly suggestive, in that multiple myeloma with gastrointestinal AL amyloidosis should be considered one of the background diseases of protein-losing enteropathy.
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FZAB, GIS, IJS, IZUM, KILJ, NLZOH, NUK, OILJ, PILJ, PNG, SAZU, SBCE, SBMB, UL, UM, UPUK
For the safe storage of zeolite wastes generated by the treatment of radioactive saline water at the Fukushima Daiichi Nuclear Power Station, this study investigated the fundamental properties of ...herschelite adsorbent and evaluated its adsorption vessel for hydrogen production and corrosion. The hydrogen produced by the herschelite sample is oxidized by radicals as it diffuses to the water surface and thus depends on the sample's water level and dissolved species. The hydrogen production rate of herschelite submerged in seawater or pure water may be evaluated by accounting for the water depth. From the obtained fundamental properties, the hydrogen concentration of a reference vessel (decay heat = 504 W) with or without residual pure water was evaluated by thermal-hydraulic analysis. The maximum hydrogen concentration was below the lower explosive limit (4%). The steady-state corrosion potential of a stainless steel 316L increased with the absorbed dose rate, but the increase was repressed in the presence of herschelite. The temperature and absorbed dose at the bottom of the 504 W vessel were determined as 60 °C and 750 Gy/h, respectively. Under these conditions, localized corrosion of a herschelite-contacted 316L vessel would not immediately occur at Cl
−
concentrations of 20,000 ppm.
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BFBNIB, GIS, IJS, KISLJ, NUK, PNG, UL, UM, UPUK
In this study, observation of the reaction of H2O2 at the surface of stainless steel utilizing electrochemical impedance spectroscopy (EIS) directly in the high purity water at 288oC was performed to ...determine the corrosive condition and the corrosion behavior of the stainless steel in high temperature and high purity water containing H2O2. Obtained results were summarized as follows; 1) The EIS data were measured directly in high temperature water without electrolyte injection. 2) The conductivity of the high temperature water at 288oC calculated by Rsol was 8.3x10-6S/cm. 3) The Rp was 9.0x103ohm*cm2 for 100ppb of H2O2, and the estimated corrosion rate was about 30μm/year. 4) The reciprocal of the polarization resistance had a linear relationship to the H2O2 concentration. It indicated that the corrosion current would be determined by the cathodic reaction of H2O2. 5) The estimated DH2O2 was 1.5x10-4cm2/s.
Objective We aimed to examine the effects of isometric handgrip (IHG) training on home blood pressure (BP) levels in hypertensive Japanese patients undergoing treatment. Methods Fifty-three ...hypertensive patients (mean age, 61.7 years; 56.6% men) with a home systolic BP ≥135 mmHg and/or a home diastolic BP ≥85 mmHg were randomly assigned to either group A or B. As per the crossover design, group A performed 8 weeks of IHG training, followed by an equivalent training-free, control period, while the reverse protocol was performed by group B. The baseline characteristics were similar between both groups. The individualized daily IHG training comprised four sets of 2-min isometric contractions at 30% of the individual's maximum voluntary contraction capacity, including 1 min of rest between sets, for ≥3 days/week. The outcome measure was morning and evening home BP readings taken over the last 2 weeks of the training and control periods. Results A combined data analysis for both groups showed that IHG training was significantly associated with the lowering of both systolic and diastolic BP in the morning (137.9±9.3 vs. 135.3±9.5 mmHg, p=0.007 and 83.0±9.5 vs. 81.2±9.3 mmHg, p<0.001, respectively) and evening (130.0±10.7 vs. 127.6±10.1 mmHg, p=0.003 and 75.8±10.4 vs. 73.8±9.2 mmHg, p<0.001, respectively), while no significant change was observed after the control period. A larger increase in the maximum grip strength due to IHG training was associated with greater BP reductions. Conclusion An 8-week period of IHG training significantly lowered both the morning and evening home BP in hypertensive Japanese patients undergoing treatment.
Purpose: The purpose of this study was to evaluate the total preparation time, the pushing and pulling forces, and the amount of canal transportation after preparing curved root canal resin models ...using the full length technique (single length technique: NF) or crown down technique (NC) with nickel titanium (Ni-Ti) rotary instrumentation (NEX NiTi FILE Ms: NEX). Methods: Transparent resin models which had curved root canals of 30 degrees were used for root canal preparation with NF, NC and stainless-steel K-files (SSK) (n=9 per group). The total preparation time and the pushing and pulling forces during preparation were measured. Photographs taken before and after preparation of the root canal were superimposed. The amount of root canal transportation was measured at 1-mm intervals from the apical foramen to the 8-mm level. The data were subjected to one-way analysis of variance followed by Bonferroni or Games-Howell multiple comparison tests (p<0.05). Results: The average total preparation time was significantly shorter in NF and NC than in SSK, but there was no significant difference between NF and NC. The average pushing and pulling forces were significantly lower in both NF and NC than in SSK, but there was no significant difference between NF and NC. There were significant differences in the amount of canal transportation between NF and SSK at positions 0, 1, 2, 4, 5, 7 and 8 mm; between NC and SSK at 0, 1, 2, 7 and 8 mm; but no significant differences between NF and NC at any position. Conclusion: Both the single length technique using NEX and the crown down technique of root canal preparation were able to properly enlarge and form the curved root canal better than SSK. The results also showed that the single length technique using NEX was effective in introducing a new root canal formation method using Ni-Ti files from the existing method using SSK.
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