Objective To assess the efficacy and safety of dietary supplements in patients with early stage prostate cancers who are managed expectantly. Methods Seventy-four patients with early prostate cancer, ...who were treated with expectant management, enrolled in the study. A mushroom mycelium extract was given at a dose of 4.5 g/day for 6 months. The primary endpoint was the proportion of patients in which the prostate specific antigen level decreased by 50% or more following treatment. The adverse events, change of prostate specific antigen value and quality of life were also evaluated. Results In only one of 74 patients (1.4%), the prostate specific antigen value decreased more than 50%. Grade 2 diarrhea and grade 1 itching were observed in one patient, and patient ingestion compliance was maintained near 100%. The alternation of prostate specific antigen values was stable before and after treatment. In subjects with strong anxiety prior to supplement ingestion, these feelings were significantly alleviated (state anxiety, P = 0.0018; trait anxiety, P = 0.0099). Conclusions In this phase II study of early prostate cancer patients who were managed expectantly, a mushroom mycelium extract was an ineffective treatment for reducing 50% or more the patient prostate specific antigen values.
The cross section, the deuteron vector A(d)(y) and tensor analyzing powers A(ij), the polarization transfer coefficients K(y('))(ij), and the induced polarization P(y(')) were measured for the dp ...elastic scattering at 270 MeV. The cross section and A(d)(y) are well reproduced by Faddeev calculations with modern data-equivalent nucleon-nucleon forces plus the Tucson-Melbourne three-nucleon force. In contrast, A(ij), K(y('))(ij), or P(y(')) are not described by such calculations. These facts indicate the deficiencies in the spin dependence of the Tucson-Melbourne force and call for extended three-nucleon force models.
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CMK, CTK, FMFMET, IJS, NUK, PNG, UM
Key aspects of the safety study of a water-cooled fusion DEMO reactor is reported. Safety requirements, dose target, DEMO plant model and confinement strategy of the safety study are briefly ...introduced. The internal hazard of a water-cooled DEMO, i.e. identification of hazardous inventories, identification of stored energies that can mobilize these hazardous inventories and identification of accident initiators and scenarios, are evaluated. It is pointed out that the enthalpy in the first wall/blanket cooling loops, the decay heat and the energy potentially released by the Be-steam chemical reaction are of special concern for the water-cooled DEMO. An ex-vessel loss-of-coolant accident (ex-VV LOCA) of the first wall/blanket cooling loop is also quantitatively analyzed. The integrity of the building against the ex-VV LOCA is discussed.
One-neutron knockout from 24O leading to the first excited state in 23O has been measured for a proton target at a beam energy of 62 MeV/nucleon. The decay energy spectrum of the neutron unbound ...state of 23O was reconstructed from the measured four momenta of the 22O fragment and emitted neutron. A sharp peak was found at Edecay=50±3 keV, corresponding to an excited state in 23O at 2.78±0.11 MeV, as observed in previous measurements. The longitudinal momentum distribution for this state was consistent with d-wave neutron knockout, providing support for a Jπ assignment of 5/2+. The associated spectroscopic factor was deduced to be C2S(0d5/2)=4.1±0.4 by comparing the measured cross section (σ−1nexp=61±6 mb) with a distorted wave impulse approximation calculation. Such a large occupancy for the neutron 0d5/2 orbital is in line with the N=16 shell closure in 24O.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
Recoiled proton tagged knockout reaction experiments were carried-out for
8He at 82.5 MeV/u in RIKEN and for
6He at 65 MeV/u in Lanzhou. The very preliminary results for the distinguish of the ...reaction mechanism are presented and compared to the kinematics calculation.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
We report for the first time the discrimination of the core fragment knockout and valence nucleon knockout reaction mechanisms at medium energy range, by the use of the recoil proton tagging ...technique. Intense 8He beams at 82.3 MeV/u were supplied by the RIPS beam line at RIKEN, and impinged on both hydrogen and carbon targets. Recoil protons were detected in coincidence with the forward moving core fragments and neutrons. The core fragment knockout mechanism is identified through the polar angle correlation and checked by various kinematics relations. This mechanism may be used to extract the cluster structure information of unstable nuclei. On the other hand, with the selection of the tagged valence nucleon knockout mechanism, a narrower peak of 7He ground state is obtained. The extracted neutron spectroscopic factor Sn=0.512(18) is relatively smaller than the no-tagged one, and is in good agreement with the prediction of ab initio Greenʼs function Monte Carlo calculations.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
A Gamow–Teller (GT) transition from the drip-line nucleus 14Be to 14B was studied via the (p,n) reaction in inverse kinematics using a secondary 14Be beam at 69 MeV/nucleon. The invariant mass method ...is employed to reconstruct the energy spectrum. A peak is observed at an excitation energy of 1.27(2) MeV in 14B, together with bumps at 2.08 and 4.06(5) MeV. The observed forward peaking of the state at 1.27 MeV and a good description for the differential cross section, obtained with a DWBA calculation provide support for the 1+ assignment to this state. By extrapolating the cross section to zero momentum transfer the GT-transition strength is deduced. The value is found to compare well with that reported in a β-delayed neutron emission study.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
The vector analyzing power has been measured for the elastic scattering of neutron-rich
6
He from polarized protons at 71 MeV/nucleon. Two approaches based on local one-body potentials were applied ...to investigate the spin-orbit interaction between a proton and a
6
He nucleus. An optical model analysis revealed that the spin-orbit potential for
6
He is characterized by a shallow and long-ranged shape compared with the global systematics of stable nuclei. A semi-microscopic analysis with a α +
n
+
n
cluster folding model suggests that the inclusion of realistic interaction between a proton and the α core is important in describing the
p
-
6
He elastic scattering.
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DOBA, EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, IZUM, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UILJ, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
An experimental study for the unbound nucleus 13Be has been performed by means of the invariant mass method via the one-neutron removal reaction H1(Be14,Be12+n). A resonance has been observed at ...0.51(1) MeV in the relative energy (Erel) spectrum of the Be12+n system. The transverse momentum distribution of the Be12+n system as well as the resonance width of 0.45(3) MeV gives evidence for the p-wave nature of the resonance. A d-wave resonance has also been observed at 2.39(5) MeV in the Erel spectrum. The observation of the low-lying p-wave resonance indicates the disappearance of the N=8 magicity in the vicinity of the neutron drip line region.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
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