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  • The Insula: An Underestimat... The Insula: An Underestimated Brain Area in Clinical Neuroscience, Psychiatry, and Neurology
    Namkung, Ho; Kim, Sun-Hong; Sawa, Akira Trends in neurosciences, 04/2017, Volume: 40, Issue: 4
    Journal Article
    Peer reviewed
    Open access

    Supported by recent human neuroimaging studies, the insula is re-emerging as an important brain area not only in the physiological understanding of the brain, but also in pathological contexts in ...
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  • Treatment resistant schizop... Treatment resistant schizophrenia: Clinical, biological, and therapeutic perspectives
    Nucifora, Frederick C.; Woznica, Edgar; Lee, Brian J. ... Neurobiology of disease, 11/2019, Volume: 131
    Journal Article
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    Open access

    Treatment resistant schizophrenia (TRS) refers to the significant proportion of schizophrenia patients who continue to have symptoms and poor outcomes despite treatment. While many definitions of TRS ...
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  • Implications for reactive o... Implications for reactive oxygen species in schizophrenia pathogenesis
    Koga, Minori; Serritella, Anthony V; Sawa, Akira ... Schizophrenia research, 09/2016, Volume: 176, Issue: 1
    Journal Article
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    Abstract Oxidative stress is a well-recognized participant in the pathophysiology of multiple brain disorders, particularly neurodegenerative conditions such as Alzheimer's and Parkinson's diseases. ...
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  • The diverse functions of GA... The diverse functions of GAPDH: Views from different subcellular compartments
    Tristan, Carlos; Shahani, Neelam; Sedlak, Thomas W. ... Cellular signalling, 02/2011, Volume: 23, Issue: 2
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    Multiple roles for glyceraldehyde-3-phosphate dehydrogenase (GAPDH) have been recently appreciated. In addition to the cytoplasm where the majority of GAPDH is located under the basal condition, ...
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  • Olfactory Functioning in Fi... Olfactory Functioning in First-Episode Psychosis
    Kamath, Vidyulata; Lasutschinkow, Patricia; Ishizuka, Koko ... Schizophrenia Bulletin, 04/2018, Volume: 44, Issue: 3
    Journal Article
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    Abstract Background Though olfactory deficits are well-documented in schizophrenia, fewer studies have examined olfactory performance profiles across the psychosis spectrum. The current study ...
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  • Minireview: Novel Micropept... Minireview: Novel Micropeptide Discovery by Proteomics and Deep Sequencing Methods
    Tharakan, Ravi; Sawa, Akira Frontiers in genetics, 05/2021, Volume: 12
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    A novel class of small proteins, called micropeptides, has recently been discovered in the genome. These proteins, which have been found to play important roles in many physiological and cellular ...
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  • Altering the course of schi... Altering the course of schizophrenia: progress and perspectives
    Millan, Mark J; Andrieux, Annie; Bartzokis, George ... Nature reviews. Drug discover/Nature reviews. Drug discovery, 07/2016, Volume: 15, Issue: 7
    Journal Article
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    Despite a lack of recent progress in the treatment of schizophrenia, our understanding of its genetic and environmental causes has considerably improved, and their relationship to aberrant patterns ...
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  • Increased power by harmoniz... Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA
    Radua, Joaquim; Vieta, Eduard; Shinohara, Russell ... NeuroImage, 09/2020, Volume: 218
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    A common limitation of neuroimaging studies is their small sample sizes. To overcome this hurdle, the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium combines neuroimaging ...
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