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  • Association of Pretreatment Circulating Tumor Tissue-Modified Viral HPV DNA With Clinicopathologic Factors in HPV-Positive Oropharyngeal Cancer
    Rettig, Eleni M; Wang, Annette A; Tran, Ngoc-Anh ... JAMA otolaryngology-- head & neck surgery, 12/2022, Volume: 148, Issue: 12
    Journal Article
    Peer reviewed
    Open access

    Circulating tumor tissue-modified viral (TTMV) human papillomavirus (HPV) DNA is a dynamic, clinically relevant biomarker for HPV-positive oropharyngeal squamous cell carcinoma. Reasons for its wide ...
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  • Additional Oncogenic Altera... Additional Oncogenic Alterations in RAS-Driven Differentiated Thyroid Cancers Associate with Worse Clinicopathologic Outcomes
    Bikas, Athanasios; Ahmadi, Sara; Pappa, Theodora ... Clinical cancer research, 07/2023, Volume: 29, Issue: 14
    Journal Article
    Peer reviewed

    RAS mutations occur across the spectrum of thyroid neoplasms, and more tools are needed for better prognostication. The objective of this study was to evaluate how additional genetic events affecting ...
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  • PD-1 antibody pembrolizumab... PD-1 antibody pembrolizumab administered at non-standard frequency in non-small cell lung cancer (NSCLC)
    Sehgal, Kartik; Shea, Meghan; McDonald, Danielle M. ... Journal of clinical oncology, 05/2019, Volume: 37, Issue: 15_suppl
    Journal Article
    Peer reviewed

    Abstract only e20617 Background: Pembrolizumab (P) administered every 3 weeks ± chemotherapy is a standard treatment option for advanced NSCLC. However, there have been no post-approval studies to ...
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  • Multifocal, Asymmetric Bila... Multifocal, Asymmetric Bilateral Primary Aldosteronism Cannot be Excluded by Strong Adrenal Vein Sampling Lateralization: An International Retrospective Cohort Study
    Turcu, Adina F; Tezuka, Yuta; Lim, Jung Soo ... Hypertension (Dallas, Tex. 1979) 81, Issue: 3
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    Primary aldosteronism (PA) has been broadly dichotomized into unilateral and bilateral forms. Adrenal vein sampling (AVS) lateralization indices (LI) ≥2 to 4 are the standard-of-care to recommend ...
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  • A novel accelerated impleme... A novel accelerated implementation of RSA using parallel processing
    Rawat, Abhishek; Sehgal, Kartik; Tiwari, Amartya ... Journal of discrete mathematical sciences & cryptography, 02/2019, Volume: 22, Issue: 2
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    Peer reviewed

    Past research has evidently proved that public key cryptosystems are usually slower than symmetric key cryptosystems due to the reason that they use one additional cryptographic key and different ...
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  • Nanoparticle-mediated combi... Nanoparticle-mediated combinatorial targeting of multiple human dendritic cell (DC) subsets leads to enhanced T cell activation via IL-15-dependent DC crosstalk
    Sehgal, Kartik; Ragheb, Ragy; Fahmy, Tarek M ... The Journal of immunology (1950), 09/2014, Volume: 193, Issue: 5
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    Most vaccines depend on coadministration of Ags and adjuvants that activate APCs. Nanoparticles (NPs) have emerged as an attractive vehicle for synchronized delivery of Ags and adjuvants to APCs and ...
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  • Derivation and external val... Derivation and external validation of a simple risk score for predicting severe acute kidney injury after intravenous cisplatin: cohort study
    Gupta, Shruti; Glezerman, Ilya G; Hirsch, Jamie S ... BMJ (Online), 03/2024, Volume: 384
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    AbstractObjectiveTo develop and externally validate a prediction model for severe cisplatin associated acute kidney injury (CP-AKI).DesignMulticenter cohort study.SettingSix geographically diverse ...
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  • Plasmacytoid dendritic cells, interferon signaling, and FcγR contribute to pathogenesis and therapeutic response in childhood immune thrombocytopenia
    Sehgal, Kartik; Guo, Xiuyang; Koduru, Srinivas ... Science translational medicine, 2013-Jul-10, Volume: 5, Issue: 193
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    Immune thrombocytopenia (ITP) is an autoimmune disorder of childhood characterized by immune-mediated destruction of platelets. The mechanisms underlying the pathogenesis of ITP and the therapeutic ...
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