For realizing flexible perovskite solar cells (PSCs), it is important to develop low‐temperature processable interlayer materials with excellent charge transporting properties. Herein, a novel ...polymeric hole‐transport material based on 1,4‐bis(4‐sulfonatobutoxy)benzene and thiophene moieties (PhNa‐1T) and its application as a hole‐transport layer (HTL) material of high‐performance inverted‐type flexible PSCs are introduced. Compared with the conventionally used poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), the incorporation of PhNa‐1T into HTL of the PSC device is demonstrated to be more effective for improving charge extraction from the perovskite absorber to the HTL and suppressing charge recombination in the bulk perovskite and HTL/perovskite interface. As a result, the flexible PSC using PhNa‐1T achieves high photovoltaic performances with an impressive power conversion efficiency of 14.7%. This is, to the best of our knowledge, among the highest performances reported to date for inverted‐type flexible PSCs. Moreover, the PhNa‐1T‐based flexible PSC shows much improved stability under an ambient condition than PEDOT:PSS‐based PSC. It is believed that PhNa‐1T is a promising candidate as an HTL material for high‐performance flexible PSCs.
By incorporating low‐temperature solution‐processable 1,4‐bis(4‐sulfonatobutoxy)benzene and thiophene moieties polymer as a hole‐transport layer, highly efficient, environmental stable, and mechanically flexible planar‐heterojunction perovskite solar cell has been successfully achieved with an excellent power conversion efficiency of 14.7%.
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BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SAZU, SBCE, SBMB, UL, UM, UPUK
Macrophages play an important role in the innate and adaptive immune responses of organ systems, including the lungs, to particles and pathogens. Cumulative results show that macrophages contribute ...to the development and progression of acute or chronic inflammatory responses through the secretion of inflammatory cytokines/chemokines and the activation of transcription factors in the pathogenesis of inflammatory lung diseases, such as acute lung injury (ALI), acute respiratory distress syndrome (ARDS), ARDS related to COVID-19 (coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)), allergic asthma, chronic obstructive pulmonary disease (COPD), and idiopathic pulmonary fibrosis (IPF). This review summarizes the functions of macrophages and their associated underlying mechanisms in the development of ALI, ARDS, COVID-19-related ARDS, allergic asthma, COPD, and IPF and briefly introduces the acute and chronic experimental animal models. Thus, this review suggests an effective therapeutic approach that focuses on the regulation of macrophage function in the context of inflammatory lung diseases.
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IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
With the development of wearable electronics, the use of engineered functional inks with printing technologies has attracted attention owing to its potential for applications in low‐cost, ...high‐throughput, and high‐performance devices. However, the improvement in conductivity and stretchability in the mass production of inks is still a challenge for practical use in wearable applications. Herein, a scalable and efficient fluid dynamics process that produces highly stretchable, conductive, and printable inks containing a high concentration of graphene is reported. The resulting inks, in which the uniform incorporation of exfoliated graphene flakes into a viscoelastic thermoplastic polyurethane is employed, facilitated the screen‐printing process, resulting in high conductivity and excellent electromechanical stability. The electrochemical analysis of a stretchable sodium ion sensor based on a serpentine‐structured pattern results in excellent electrochemical sensing performance even under strong fatigue tests performed by repeated stretching (300% strain) and release cycles. To demonstrate the practical use of the proposed stretchable conductor, on‐body tests are carried out in real‐time to monitor the sweat produced by a volunteer during simultaneous physical stretching and stationary cycling. These functional graphene inks have attractive performance and offer exciting potential for a wide range of flexible and wearable electronic applications.
Highly stretchable, conductive, and printable graphene inks are fabricated using a fluid dynamics process, resulting in excellent electrochemical sensing performance of a potentiometric ion sensor even under a high level of a strain of 300%. Using a stretchable sensor on‐body tests are demonstrated in real‐time to monitor the sweat produced by a volunteer during simultaneous physical stretching and stationary cycling.
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BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SAZU, SBCE, SBMB, UL, UM, UPUK
A 7-bit 3 GS/s two-channel time-interleaved two-step flash analog-to-digital converter (ADC) with 7-GHz effective resolution bandwidth (ERBW) is presented. A reference-embedding flash ADC for a fine ...stage having only a single capacitive digital-to-analog converter improves the power efficiency and area efficiency as well as the input bandwidth. The proposed sample-and-hold sharing structure not only improves the input bandwidth by removing the effect of the input capacitance of the fine ADC (FADC) but also eliminates the gain error between the coarse ADC and the FADC. The advanced sequential slope-matching offset calibration technique in the eight-time interpolated FADC improves the gain of the voltage-to-time converter and the interpolation linearity. A prototype ADC implemented in a 40-nm CMOS process occupies 0.03 mm 2 , including offset calibration circuitry. The measured peak differential non-linearity (DNL) and integral non-linearity (INL) after calibration are 0.53 and 0.47 LSB, respectively. With a 1.49-GHz input, the measured signal-to-noise and distortion ratio (SNDR) and spurious-free dynamic range (SFDR) are 39.94 and 55.78 dB, respectively. The ERBW without and with time skew calibration is 4.8 and 7 GHz, respectively. The power consumption is 6.8 mW under a supply voltage of 0.9 V, leading to a figure of merit (FoM) of 28 fJ/conversion-step at 3 GS/s.
Due to the increasing interest in wearable devices, flexible and stretchable film heaters have been widely studied, as alternatives to heaters with conventional rigid shapes. Herein, a highly ...stretchable film heater (SFH) based on the silver nanowire (Ag NW)–single‐walled carbon nanotube composite with a thermochromic display on a polydimethylsiloxane (PDMS) substrate is successfully fabricated. The SFH shows excellent electrical conductivity, high mechanical stretchability, and outstanding reliability, with no significant degradation after 10 000 stretching cycles under tensile strain. The SFH can be heated to the target temperature (≈60 °C) within 30 s at a low applied voltage. In addition, a thermochromic display is fabricated to help prevent the risk of low‐temperature burns. Red (R), green (G), and blue (B) thermochromic microparticles (TMPs) are synthesized using drop‐based microfluidic technology. The TMPs show RGB colors at room temperature but change to a white color above a certain temperature. The TMPs are arrayed into a PDMS stencil on the basis of their particle sizes using the rubbing technique. The micropatterned thermochromic display, which functions as a visual alarm, combined with the SFH can pave the way for the development of thermotherapy pads for next‐generation wearable devices in the medical field.
A highly stretchable and wearable thermotherapy pad with a micropatterned thermochromic display based on a Ag nanowire–single‐walled carbon nanotube composite is demonstrated. It has a low resistance, high stretchability, and excellent reliability. Moreover, the thermochromic display has a built‐in visual alarm mechanism to prevent low‐temperature burns. This promising articular thermotherapy pad has potential applications in the medical field.
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BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SAZU, SBCE, SBMB, UL, UM, UPUK
This paper proposes a novel approach for automatic 3D surface reconstruction from uncalibrated and multi-view Google Earth images by using a multi-view stereo method and 3D projective to metric ...transformation. Without the Rational Polynomial Coefficients, it is impossible to obtain the metric reconstruction of the 3D surface from multi-view satellite images. We solve the uncalibrated multi-view satellite image problem by employing a multi-view stereo vision technique followed by a projective to metric transformation. The virtual pose parameters of the satellite images are obtained by using COLMAP, and the virtual 3D projective reconstruction is done by using EnSoft3D. For projective to metric transformation, we propose to employ 3D homography transformation. Eight 3D correspondence pairs on the viewing frustums between the virtual reference camera and the ideal nadir camera are used to derive a 3D homography matrix. Using the 3D homography matrix, we finally obtain the metric reconstruction of 3D surface up to an unknown height scale in a reference coordinate system of the Google Earth desktop software. Experiments are done in several world locations on Google Earth including building and vegetation areas. Reconstruction error analysis with the Data Fusion Contest 19 dataset is also presented. The average of MAE and RMSE of five tile regions in the dataset are 1.596 m and 2.083 m, respectively.
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BFBNIB, GIS, IJS, KISLJ, NUK, PNG, UL, UM, UPUK
Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD). The gut microbiota regulates intestinal immune homeostasis, but the role of ...Axl in the pathogenesis of IBD through the regulation of gut microbiota composition remains unresolved. In this study, mice with DSS-induced colitis showed increased Axl expression, which was almost entirely suppressed by depleting the gut microbiota with antibiotics. Axl
mice without DSS administration exhibited increased bacterial loads, especially the Proteobacteria abundant in patients with IBD, significantly consistent with DSS-induced colitis mice. Axl
mice also had an inflammatory intestinal microenvironment with reduced antimicrobial peptides and overexpression of inflammatory cytokines. The onset of DSS-induced colitis occurred faster with an abnormal expansion of Proteobacteria in Axl
mice than in WT mice. These findings suggest that a lack of Axl signaling exacerbates colitis by inducing aberrant compositions of the gut microbiota in conjunction with an inflammatory gut microenvironment. In conclusion, the data demonstrated that Axl signaling could ameliorate the pathogenesis of colitis by preventing dysbiosis of gut microbiota. Therefore, Axl may act as a potential novel biomarker for IBD and can be a potential candidate for the prophylactic or therapeutic target of diverse microbiota dysbiosis-related diseases.
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IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
Repetitive exposure to ultraviolet B (UVB) is one of the main causes of skin photoaging. We previously reported that dieckol isolated from
extract has potential anti-photoaging effects in ...UVB-irradiated Hs68 cells. Here, we aimed to evaluate the anti-photoaging activity of dieckol in a UVB-irradiated hairless mouse model. In this study, hairless mice were exposed to UVB for eight weeks. At the same time, dieckol at two doses (5 or 10 mg/kg) was administered orally three times a week. We found that dieckol suppressed UVB-induced collagen degradation and matrix metalloproteinases (MMPs)-1, -3, and -9 expression by regulating transforming growth factor beta (TGF-β)/Smad2/3 and mitogen-activated protein kinases (MAPKs)/activator protein-1 (AP-1) signaling. In addition, dieckol rescued the production of hyaluronic acid (HA) and effectively restored the mRNA expression of hyaluronan synthase (HAS)-1/-2 and hyaluronidase (HYAL)-1/-2 in UVB-irradiated hairless mice. We observed a significant reduction in transepidermal water loss (TEWL), epidermal/dermal thickness, and wrinkle formation in hairless mice administered dieckol. Based on these results, we suggest that dieckol, due to its anti-photoaging role, may be used as a nutricosmetic ingredient for improving skin health.
This article presents an energy-efficient high-resolution dual-residue (D-R) pipelined-successive approximation register (SAR) analog-to-digital converter (ADC), with a backend capacitive ...interpolating SAR ADC incorporated with noise-shaping (NS) capability. The residue amplifier design could be simplified as the residue is pre-amplified by the amplifier for the kT/<inline-formula> <tex-math notation="LaTeX">C </tex-math></inline-formula>-noise cancellation. Moreover, the proposed segmented digital-to-analog converter (DAC) structure overcomes parasitic capacitance limitations in the capacitive interpolation, improving resolution along with the gain-error-free advantage of the D-R structure. Fabricated in a 180-nm CMOS technology, the prototype ADC achieves an 81.2-dB signal-to-noise and distortion ratio (SNDR) and an 89.9-dB spurious-free dynamic range (SFDR) in a 1.5-MHz bandwidth (BW) at an over-sampling ratio (OSR) of 8 with a 170.4-dB SNDR Schreier figure-of-merit (FoM) without any calibration.
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