Using 2.93 fb–1 of e+e– collision data collected at a center-of-mass energy of 3.773 GeV with the BESIII detector, the first observation of the doubly Cabibbo-suppressed decay D+ → K+π+π–π0 is ...reported. After removing decays that contain narrow intermediate resonances, including D+ → K+η , D+ → K+ω, and D+ → K+Φ, the branching fraction of the decay D+ → K+π+π–π0 is measured to be (1.13 ± 0.08stat ± 0.03syst) × 10–3. The ratio of branching fractions of D+ → K+π+π–π0 over D+ → K–π+π+π0 is found to be (1.81 ± 0.15)%, which corresponds to (6.28 ± 0.52) tan4 θC, where θC is the Cabibbo mixing angle. This ratio is significantly larger than the corresponding ratios for other doubly Cabibbo-suppressed decays. The asymmetry of the branching fractions of charge-conjugated decays D± → K±π±π∓π0 is also determined, and no evidence for CP violation is found. In addition, the first evidence for the D+ → K+ω decay, with a statistical significance of 3.3σ, is presented and the branching fraction is measured to be B(D+ → K+ω) = (5.7 $^{+2.5}_{–2.1 stat}$ ± 0. 2syst) × 10–5.
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CMK, CTK, FMFMET, IJS, NUK, PNG, UL, UM
Based on e+e- collision data sample corresponding to an integrated luminosity of 2.93 fb-1 taken at a center-of-mass energy of 3.773 GeV by the BESIII detector, we report the measurements of the ...absolute branching fractions of D0 → K+K-π0π0 , D0 → KS0KS0π+π- , D0 → KS0K-π+π0 , D0 → KS0K+π-π0 , D+ → K+K-π+π0 , D+ → KS0K+π0π0 , D+ → KS0K-π+π+ , D+ → KS0K+π+π- , and D+ → KS0KS0π+π0 . The decays D0 → K+K-π0π0 , D0 → KS0K-π+π0 , D0 → KS0K+π-π0 , D+ → KS0KS0π+π0 , and D+ → KS0K+π0π0 are observed for the first time. The branching fractions of the decays D0 → KS0KS0π+π- , D+ → K+K-π+π0 , D+ → KS0K-π+π+ , and D+ → KS0K+π+π- are measured with improved precision compared to the world-average values.
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CMK, CTK, FMFMET, IJS, NUK, PNG, UM
Background Few prospective data from the Asia-Pacific region are available relating body mass index (BMI) to the risks of stroke and ischaemic heart disease (IHD). Our objective was to assess the ...age-, sex-, and region-specific associations of BMI with cardiovascular disease using individual participant data from prospective studies in the Asia-Pacific region. Methods Studies were identified from literature searches, proceedings of meetings, and personal communication. All studies had at least 5000 person-years of follow-up. Hazard ratios were calculated from Cox models, stratified by sex and cohort, and adjusted for age at risk and smoking. The first 3 years of follow-up were excluded in order to reduce confounding due to disease at baseline. Results A total of 33 cohort studies, including 310 283 participants, contributed 2 148 354 person-years of follow-up, during which 3332 stroke and 2073 IHD events were observed. There were continuous positive associations between baseline BMI and the risks of ischaemic stroke, haemorrhagic stroke, and IHD, with each 2 kg/m2 lower BMI associated a 12% (95% CI: 9, 15%) lower risk of ischaemic stroke, 8% (95% CI: 4, 12%) lower risk in haemorrhagic stroke, and 11% (95% CI: 9, 13%) lower risk of IHD. The strengths of all associations were strongly age dependent, and there was no significant difference between Asian and Australasian cohorts. Conclusions This overview provides the most reliable estimates to date of the associations between BMI and cardiovascular disease in the Asia-Pacific region, and the first direct comparisons within the region. Continuous relationships of approximately equal strength are evident in both Asian and Australasian populations. These results indicate considerable potential for cardiovascular disease reduction with population-wide lowering of BMI.
We collected observational data on 781 Wolf-Rayet (WR) galaxies from the literature to photometrically study their infrared properties measured by the 2MASS, WISE, IRAS, AKARI, and Herschel missions. ...It is found that in the 1-5 m range the radiations of WR galaxies are dominated by the free-free emissions from the stellar winds and the circumstellar dust from the late-type stars in the host galaxy. In the 5-22 m range, the radiation of WR galaxies is dominated by the free-free emissions and the synchrotron radiation from the central active galactic nucleus (AGN; but not always present). In the 22-140 m range, the radiations of WR galaxies are dominated by the free-free emissions and the star formation/starburst activities. In the 250-500 m range, the radiation of WR galaxies is dominated by the free-free emissions. In addition, the comparison with the non-WR galaxies is made. It is shown that some star formation WR galaxies have redder near-infrared colors than non-WR star-forming galaxies probably due to the gas emission in the near-infrared. In the 2-5 m region WR galaxies have redder colors due to the thermal emission from circumstellar dust of late-type stars and the enhanced gas emission. In the 5-22 m region, both WR galaxies and non-WR galaxies have similar behavior, indicative of having similar free-free emission as the dominant radiation. In the 25-140 m region, both types of galaxies also have similar behavior, indicative of having free-free emission from the stellar winds or the thermal radiation from the starburst/star formation as the dominant radiation.
ABSTRACT
Background Maternal thyroid hormone deficiency is the most common disorder of thyroid function during pregnancy and can influence the outcome for mother and foetus. The purpose of this ...study was to investigate the prevalence of thyroid hormone deficiency during the first half of pregnancy in iodine sufficient areas of China.
Materials and methods Four thousand eight hundred pregnant women from 10 hospitals during the first 20 weeks of gestation were enrolled in this study. All sera obtained from pregnant women were measured for thyrotropin, free thyroxine and thyroid peroxidase antibody. Screening for thyroid hormone deficiency was performed on pregnant women using gestational age‐specific reference intervals or non‐pregnant population reference intervals.
Results With gestational age‐specific reference intervals as the criterion, the prevalence of subclinical hypothyroidism at 4, 8, 12,16 and 20 weeks of gestation was 4·59%, 6·15%, 4·68%, 4·53% and 5·96%, respectively, and the prevalence of hypothyroxinaemia was 3·69%, 1·11%, 2·92%, 1·29% and 2·29%, respectively. Different prevalence was obtained when non‐pregnant population reference intervals was used as the criterion.
If non‐pregnant population reference intervals were used, the percentage of potentially misclassified cases of subclinical hypothyroidism were 0·18%, 2·85%, 4·1%, 3·24%, and 3·21%, respectively, and 3·45%, 0·66%, 2·34%, 1·29%, and 1·83%, respectively, in potentially misclassified cases of hypothyroxinaemia.
Conclusions The percentage of potentially misclassified cases of subclinical hypothyroidism and hypothyroxinaemia in pregnant women decreased by using the gestational age‐specific reference intervals as a diagnostic criteria during the first half of pregnancy.
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BFBNIB, DOBA, FZAB, GIS, IJS, IZUM, KILJ, NLZOH, NUK, OILJ, PILJ, PNG, SAZU, SBCE, SBMB, SIK, UILJ, UKNU, UL, UM, UPUK
In plant cells, anion channels and transporters are essential for key functions. Members of the chloride channel (CLC) family located in intracellular organelles are required for anion accumulation, ...pH adjustment, and salt tolerance. Here, we cloned a maize (Zea mays L.) CLC gene, named ZmCLC-d, and found that its transcription was up-regulated under cold, drought, salt, and heat stresses, and after hydrogen peroxide (H₂O₂) and abscisic acid (ABA) treatments. The overexpression of ZmCLC-d in Arabidopsis conferred tolerance to cold, drought, and salt stresses; this tolerance was primarily displayed by an increased germination rate, root length, plant survival rate, antioxidant enzyme (catalase, peroxidase, and superoxide dismutase) activities, and a reduced accumulation of Cl⁻in transgenic plants as compared with wild type (WT) plants. The accumulation of H₂O₂and superoxide anion in leaves of the ZmCLC-d-overexpressing plants is much less than that of the WT plants. The expressions of some stress related genes, such as CBF1, CBF2, CBF3, DREB2A, and RCI2A, increased to a greater extent in the ZmCLC-d-overexpressing plants than in the WT. Our results strongly suggest that ZmCLC-d played an important role in stress tolerance.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NUK, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UL, UM, UPUK, VKSCE, ZAGLJ
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