The purpose of this column is to describe the implementation of an international multisite Roy adaptation model-based study of women’s perceptions of and responses to cesarean birth. The need for the ...study arose from the concern that women’s childbearing needs may not be met to their full satisfaction, especially if the infant is born by cesarean. Serendipity and networking played a part in the selection of four study sites in the United States (Boston, Milwaukee, Norfolk, Oklahoma City) and two in other countries (Finland, Australia). Data were collected by nursing students and staff nurses. Post-hoc consideration of the diversity of study sites revealed opportunities for examination of the influence of the contextual stimuli of culture and geographic region on the women’s adaptation to cesarean birth. Strategies used to foster integration of teaching, practice, and research are discussed.
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NUK, OILJ, SAZU, UKNU, UL, UM, UPUK
Dans cet article, nous présentons une étude sur l'expérience des conducteurs d'applis, menée au premier semestre 2020, pendant les mois de verrouillage dus à la pandémie de Covid19. Dans un premier ...temps, nous développons une brève revue de la littérature sur les transformations du monde du travail, puis une étude préliminaire sur la structure professionnelle brésilienne basée sur les statistiques disponibles de l'Institut brésilien de géographie et de statistique (IBGE). Au Brésil, le taux de chômage a augmenté ces dernières années, et avec lui, l'informalité a également augmenté, c'est-à-dire que le nombre de travailleurs sans contrat de travail signé a augmenté, et donc, sans la garantie des droits du travail. Nous pouvons observer au cours des trois dernières années une augmentation significative du nombre de conducteurs et de coursiers d'apps. Cette catégorie, pour ne pas avoir de droits du travail, est confrontée à la précarité, car elle travaille pour des entreprises multinationales qui profitent beaucoup, sans aucun lien d'emploi. Cette réalité est devenue encore plus évidente en période de crise, comme dans le cas de la pandémie de coronavirus, lorsque ces travailleurs ne pouvaient pas respecter les règles d'isolement, car s'ils ne travaillent pas, ils ne peuvent pas subvenir aux besoins de leur famille. La recherche vise à contribuer à la compréhension des changements dans les relations de travail causés par l'avancement des outils numériques qui facilitent l'échange de services. Pour ce faire, trois objectifs spécifiques ont été fixés : i) cartographier le débat dans la littérature spécialisée sur les relations de travail médiées par la popularisation des applications de prestation de services ; ii) explorer les statistiques disponibles auprès de l'Institut brésilien de géographie et de statistique (IBGE) sur le sujet et présenter une étude exploratoire sur le profil des moteurs d'application. Les statistiques publiques sur la population économiquement active seront examinées et des informations sur les trajectoires professionnelles des prestataires de services seront collectées. Une discussion plus approfondie est attendue sur la façon dont ces outils de prestation de services sont liés au travail et comment ils modifient ces relations à partir du moment historique, économique et politique. Ils permettront également de contribuer à la production d'informations socio-démographiques sur ces travailleurs, sur lesquels nous ne disposons pratiquement d'aucune statistique.
To determine the nephron segment distribution of tubular epithelial damage and regeneration and the proliferative activity of various nephron segments in human acute tubular necrosis (ATN) with an ...antibody to proliferating cell nuclear antigen (PCNA) and to compare the findings in native kidneys with ATN with those in transplant kidneys with ATN, archival tissues from 12 native and 21 transplant kidney biopsy specimens and nine transplant nephrectomy specimens were collected that all showed obvious morphological signs of ATN. Nineteen patients with transplant kidneys with ATN were immunosuppressed with cyclosporine and 11 were immunosuppressed with prednisone and azathioprine. There was a predominance of “regenerating” tubules (tubules with thin epithelium) in the distal nephron in native kidneys with ATN; in the transplant kidneys this was less conspicuous. The number of Tamm-Horsfall protein (THP)-positive tubules was decreased in all kidneys with ATN compared with normal human kidneys. In contrast, the number of THP-positive casts was much higher in all kidneys with ATN than in the normal kidneys. In transplant kidneys with ATN the number of THP-positive casts was substantially lower than in native kidneys with ATN. The macula densa appears to maintain its morphological integrity in kidneys with ATN. Both regenerating and normal appearing tubules expressed vimentin and HLA-DR. The proliferation index (PI; ie, percentage of PCNApositive nuclei) of the renal tubular epithelium in normal control kidneys varied between 0.22 and 0.33, depending on the tubule segment. The highest PI was noted in the transplant kidneys with ATN not treated with cyclosporine (8.0), followed by the native kidneys with ATN (4.4) and the transplant kidneys with ATN treated with cyclosporine (4.3). We did not find any significant difference in the PI between the regenerating (5.0) and normal appearing (5.6) tubules. Proximal tubules (8.7) showed significantly higher PI values than distal tubules (3.5) in transplant kidneys with ATN. Our results show substantial differences between native kidneys and transplant kidneys with ATN. Tubular epithelial cell proliferation in human ATN is prominent and appears to correlate with the severity of ATN. Light microscopically normal appearing tubules and regenerating tubules participate equally in the regeneration of injured tubules. Cyclosporine may have an inhibitory effect on cell regeneration (proliferation) in human transplant kidneys with ATN.
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IJS, IMTLJ, KILJ, KISLJ, NUK, SBCE, SBJE, UL, UM, UPCLJ, UPUK
We have carried out a retrospective, multicentre, chart-review trial, in which all the patients meeting pre-established inclusion criteria and treated in the three participating centres with either ...splenectomy or low-dose splenic irradiation were enrolled. Inclusion criteria were: long-lasting, symptomatic, severe thrombocytopenia (<25 x 10 super(9)/l), refractory to previous treatments (zidovudine; corticosteroids; vincristine; danazol; high-dose intravenous IgG; high-dose dexamethasone or IFN- alpha ) and a CD4 cell count higher than 50 x 10 super(6)/l. Exclusion criteria were: reduced bone marrow megakaryocytes; liver cirrhosis; granulocytes lower than 3 x 10 super(9)/l or haemoglobin lower than 110 g/l; allergy to pneumococcal vaccine or to cephalosporins. Patient records were analysed for a follow-up of 6 months by independent reviewers.
Gingivitis and periodontitis are immunoinflammatory periodontal diseases characterized by chronic localized infections usually associated with insidious inflammation This narrative review discusses ...periodontal diseases and mechanisms influencing the immune response and autoimmunity in pediatric rheumatic diseases (PRD), particularly juvenile idiopathic arthritis (JIA), childhood-onset systemic lupus erythematosus (C-SLE) and juvenile dermatomyositis (JDM). Gingivitis was more frequently observed in these diseases compared to health controls, whereas periodontitis was a rare finding. In JIA patients, gingivitis and periodontitis were related to mechanical factors, chronic arthritis with functional disability, dysregulation of the immunoinflammatory response, diet and drugs, mainly corticosteroids and cyclosporine. In C-SLE, gingivitis was associated with longer disease period, high doses of corticosteroids, B-cell hyperactivation and immunoglobulin G elevation. There are scarce data on periodontal diseases in JDM population, and a unique gingival pattern, characterized by gingival erythema, capillary dilation and bush-loop formation, was observed in active patients. In conclusion, gingivitis was the most common periodontal disease in PRD. The observed association with disease activity reinforces the need for future studies to determine if resolution of this complication will influence disease course or severity.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
The Brazilian Amazon is an area of both serious environmental degradation and social instability. Despite billions of dollars spent on economic development and the rapid pace of urbanization, ...deforestation is extreme and violent land conflict is intense. Although episodes of conflict over land are common in Brazilian history, this paper focuses on agrarian issues that arose with the opening of the Amazon frontier in the 1970s. The paper argues that the nature of land conflict in the eastern Brazilian Amazon is dynamic, and proposes a two-stage model to illustrate how the struggle has evolved from an agrarian phenomenon to an organized resistance that is urban-based. Recognizing the interaction between cities and rural areas in the frontier reaches of the Brazilian Amazon is key to understanding the land struggle in the face of urbanization. The analytical framework deployed considers the transformation of the region from an agrarian frontier to an urbanized frontier, assessing the dynamic nature of the land struggle and examining the implications for land cover change.
High-luminosity fixed-target experiments at the LHC
Proceedings of International Conference on Hard and Electromagnetic Probes of High-Energy Nuclear Collisions — PoS(HardProbes2018)
Conference Proceeding
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