Temporomandibular joint ankylosis which is most frequently caused by trauma, presents with restriction in mouth opening in early stages and if children are the victim and not treated early, it ...presents with growth retardation of the involved mandibular side. Various methods are available for surgical correction. We have reviewed our experience with the efficacy of different interpositional materials in post-traumatic cases in our set up with special reference to temporal fascia over last three years. Twenty seven patients with history of trauma, mostly fall from height, have been studied. They were evaluated clinically and by computed tomography (CT) scan, orthopantogram and x- ray lateral oblique view. The most common age group was 10-15 years with mean 12.5 years and male to female ratio 1:2. Preoperative mouth opening (inter incisor distance) was 1-2 mm in 17 cases and 2-4 mm in 10 cases. We have used temporalis fascia in nine, costochondral graft in seven, silastic sheets in five and T-plates in six cases. Post-operatively, adequate mouth opening of 30-50 mm was observed in six months follow-up and more than 50 mm at one year follow up in 21 cases out of which nine cases have interpositional material as temporalis fascia alone. The postoperative period was uneventful in all cases and none required re-operation for recurrences. We conclude that interpositional arthroplasty, especially with pedicled temporal fascia, is the best method to prevent recurrences and establish good mouth opening and full range of jaw movements.
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DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
Temporomandibular joint ankylosis which is most frequently caused by
trauma, presents with restriction in mouth opening in early stages and
if children are the victim and not treated early, it ...presents with
growth retardation of the involved mandibular side. Various methods are
available for surgical correction. We have reviewed our experience with
the efficacy of different interpositional materials in post-traumatic
cases in our set up with special reference to temporal fascia over last
three years. Twenty seven patients with history of trauma, mostly fall
from height, have been studied. They were evaluated clinically and by
computed tomography (CT) scan, orthopantogram and x- ray lateral
oblique view. The most common age group was 10-15 years with mean 12.5
years and male to female ratio 1:2. Preoperative mouth opening (inter
incisor distance) was 1-2 mm in 17 cases and 2-4 mm in 10 cases. We
have used temporalis fascia in nine, costochondral graft in seven,
silastic sheets in five and T-plates in six cases. Post-operatively,
adequate mouth opening of 30-50 mm was observed in six months follow-up
and more than 50 mm at one year follow up in 21 cases out of which nine
cases have interpositional material as temporalis fascia alone. The
postoperative period was uneventful in all cases and none required
re-operation for recurrences. We conclude that interpositional
arthroplasty, especially with pedicled temporal fascia, is the best
method to prevent recurrences and establish good mouth opening and full
range of jaw movements.
Full text
Available for:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
Temporomandibular joint ankylosis which is most frequently caused by trauma, presents with restriction in mouth opening in early stages and if children are the victim and not treated early, it ...presents with growth retardation of the involved mandibular side. Various methods are available for surgical correction. We have reviewed our experience with the efficacy of different interpositional materials in post-traumatic cases in our set up with special reference to temporal fascia over last three years. Twenty seven patients with history of trauma, mostly fall from height, have been studied. They were evaluated clinically and by computed tomography (CT) scan, orthopantogram and x- ray lateral oblique view. The most common age group was 10-15 years with mean 12.5 years and male to female ratio 1:2. Preoperative mouth opening (inter incisor distance) was 1-2 mm in 17 cases and 2-4 mm in 10 cases. We have used temporalis fascia in nine, costochondral graft in seven, silastic sheets in five and T-plates in six cases. Post-operatively, adequate mouth opening of 30-50 mm was observed in six months follow-up and more than 50 mm at one year follow up in 21 cases out of which nine cases have interpositional material as temporalis fascia alone. The postoperative period was uneventful in all cases and none required re-operation for recurrences. We conclude that interpositional arthroplasty, especially with pedicled temporal fascia, is the best method to prevent recurrences and establish good mouth opening and full range of jaw movements.
Full text
Available for:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
AbstractObjectiveTo investigate the effectiveness of using convalescent plasma to treat moderate coronavirus disease 2019 (covid-19) in adults in India.DesignOpen label, parallel arm, phase II, ...multicentre, randomised controlled trial.Setting39 public and private hospitals across India.Participants464 adults (≥18 years) admitted to hospital (screened 22 April to 14 July 2020) with confirmed moderate covid-19 (partial pressure of oxygen in arterial blood/fraction of inspired oxygen (PaO2/FiO2) ratio between 200 mm Hg and 300 mm Hg or a respiratory rate of more than 24/min with oxygen saturation 93% or less on room air): 235 were assigned to convalescent plasma with best standard of care (intervention arm) and 229 to best standard of care only (control arm).InterventionsParticipants in the intervention arm received two doses of 200 mL convalescent plasma, transfused 24 hours apart. The presence and levels of neutralising antibodies were not measured a priori; stored samples were assayed at the end of the study.Main outcome measureComposite of progression to severe disease (PaO2/FiO2 <100 mm Hg) or all cause mortality at 28 days post-enrolment.ResultsProgression to severe disease or all cause mortality at 28 days after enrolment occurred in 44 (19%) participants in the intervention arm and 41 (18%) in the control arm (risk difference 0.008 (95% confidence interval −0.062 to 0.078); risk ratio 1.04, 95% confidence interval 0.71 to 1.54).ConclusionConvalescent plasma was not associated with a reduction in progression to severe covid-19 or all cause mortality. This trial has high generalisability and approximates convalescent plasma use in real life settings with limited laboratory capacity. A priori measurement of neutralising antibody titres in donors and participants might further clarify the role of convalescent plasma in the management of covid-19.Trial registrationClinical Trial Registry of India CTRI/2020/04/024775.
Machine learning (ML) methods are becoming popular tools for predicting and designing novel materials. In particular, neural network (NN) is a promising ML method, which can be used to identify ...hidden trends in the data. However, these methods rely on a large dataset and often exhibit overfitting when used with a sparse dataset. Further, assessing the uncertainty in predictions for a new dataset or an extrapolation of the present dataset is challenging. Herein, using Gaussian process regression (GPR), we predict Young's modulus for silicate glasses having a sparse dataset. We show that GPR significantly outperforms NN for the sparse dataset while ensuring no overfitting. Further, thanks to the nonparametric nature, GPR provides quantitative bounds for the reliability of predictions while extrapolating. Overall, GPR presents an advanced ML methodology for accelerating the development of novel functional materials such as glasses.
•Machine learning is used to predict Young's modulus of glasses with sparse data.•Neural network and polynomial regression may exhibit overfitting for sparse data.•Gaussian process (GP) regression exhibits superiority while training on sparse data.•Ability to provide the uncertainty in predictions makes GP regression reliable.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
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