A Nationwide Nitrogen Deposition Monitoring Network (NNDMN) containing 43 monitoring sites was established in China to measure gaseous NH3, NO2, and HNO3 and particulate NH4+ and NO3− in air and/or ...precipitation from 2010 to 2014. Wet/bulk deposition fluxes of Nr species were collected by precipitation gauge method and measured by continuous-flow analyzer; dry deposition fluxes were estimated using airborne concentration measurements and inferential models. Our observations reveal large spatial variations of atmospheric Nr concentrations and dry and wet/bulk Nr deposition. On a national basis, the annual average concentrations (1.3–47.0 μg N m−3) and dry plus wet/bulk deposition fluxes (2.9–83.3 kg N ha−1 yr−1) of inorganic Nr species are ranked by land use as urban > rural > background sites and by regions as north China > southeast China > southwest China > northeast China > northwest China > Tibetan Plateau, reflecting the impact of anthropogenic Nr emission. Average dry and wet/bulk N deposition fluxes were 20.6 ± 11.2 (mean ± standard deviation) and 19.3 ± 9.2 kg N ha−1 yr−1 across China, with reduced N deposition dominating both dry and wet/bulk deposition. Our results suggest atmospheric dry N deposition is equally important to wet/bulk N deposition at the national scale. Therefore, both deposition forms should be included when considering the impacts of N deposition on environment and ecosystem health.
The registration data of local cancer registries in 2014 were collected by National Central Cancer Registry (NCCR)in 2017 to estimate the cancer incidence and mortality in China.
The data submitted ...from 449 registries were checked and evaluated, and the data of 339 registries out of them were qualified and selected for the final analysis. Cancer incidence and mortality were stratified by area, gender, age group and cancer type, and combined with the population data of 2014 to estimate cancer incidence and mortality in China. The age composition of standard population of Chinese census in 2000 and Segi's population were used for age-standardized incidence and mortality in China and worldwide, respectively.
Total covered population of 339 cancer registries (129 in urban and 210 in rural) in 2014 were 288 243 347 (144 061 915 in urban and 144 181 432 in rural areas). The mortality verified cases (MV%) were 68.01%. Among them, 2.19% cases were identified through death certifications only (DCO%), and the mortality
Tibetan Plateau uplift has been suggested as the main driving force for mid-latitude Asian inland aridity (AIA) and for deposition of thick aeolian sequences in northern China since the Miocene. ...However, the relationship between earlier AIA and Tibetan Plateau mountain building is uncertain because of a lack of corresponding thick aeolian sequences with accurate age constraints. We here present results for a continuous aeolian sequence that spans the interval from >51 to 39 Ma from the eastern Xorkol Basin, Altun Shan, northeastern Tibetan Plateau. The basal age of the studied sequence postdates initial uplift of the Tibetan Plateau by several million years. Our results indicate that the local palaeoclimate was teleconnected strongly to the overall global cooling pattern, so that local enhanced aridification recorded by the studied aeolian sequence is dominantly a response to global climatic forcing rather than plateau uplift.
Chemoradiotherapy is regarded as a standard scheme for inoperable and unresectable esophageal cancers. Our aims were to explore the prognostic factors relevant to esophageal squamous cell carcinoma ...(ESCC) following intensity-modulated radiation therapy (IMRT) plus chemotherapy.
Totally 495 ESCC patients undergoing IMRT combined with chemotherapy in our hospital between 2011 and 2020 were retrospectively analyzed. Potential clinical prognosis-related factors were assessed by uni- and multivariate analyses.
The median overall survival (OS) and progression-free survival (PFS) of the ESCC patients were 2.25 and 1.24years, respectively. Uni- and multivariate analyses demonstrated the relevant independent prognostic factors of OS and PFS were gender, T stage, N stage, clinical stage, and tumor location (P<0.05), but not chemotherapy or radiotherapy dose. We further compared the 5-year OS rates among different T stages, N stages, clinical stages, genders, and tumor locations. The survival rate at the higher clinical stage was significantly lower (P<0.001). The 5-year OS in the upper thorax of the tumor was 46.0% and exceeded other tumor locations (P<0.05). The 5-year OS was 56.1% among females and 33.3% among males (P=0.001).
For ESCC patients receiving IMRT combined with chemotherapy, their long-term curative effects are influenced by T stages, N stages, clinical stages, genders, and tumor locations. ESCC patients who are females, or have upper thoracic tumor, or are at early clinical stage own better prognosis.
La chimioradiothérapie est utilisée comme traitement standard pour des cancers de l’œsophage inopérables et non résécables. L’objectif de l’étude était l’analyse les facteurs pronostiques significatifs de carcinomes épidermoïdes de l’œsophage après une radiothérapie avec modulation d’intensité (RCMI) et une chimiothérapie.
L’analyse rétrospective a inclus 495 patients atteints de cancer de carcinome épidermoïde de l’œsophage pris en charge par RCMI et chimiothérapie dans notre hôpital entre 2011 et 2020. Des analyses uni- et multifactorielles ont ensuite été effectuées pour évaluer les facteurs potentiels liés au pronostic clinique.
Les médianes de survie globale et de survie sans progression étaient respectivement de 2,25 et 1,24 ans. Des analyses uni- et multifactorielles ont révélé que les facteurs pronostiques indépendants pertinents pour la survie globale et de la survie sans progression étaient liés au sexe, au stade T, N, au stade clinique et à la localisation tumorale (p<0,05), et non à la dose de chimiothérapie ou de radiothérapie. Nous avons ensuite comparé les taux de survie à 5 ans entre les différents stades T, N, cliniques, sexes et localisations tumorales. Le taux de survie pour le stade clinique supérieur était significativement plus faible (p<0,001). Le taux de survie globale à 5 ans dans le cas des tumeurs du thorax supérieur était de 46,0 %, supérieur à celui pour les autres localisations tumorales (p<0,05). Le taux de survie globale à 5 ans était de 56,1 % chez les femmes et de 33,3 % chez les hommes (p=0,001).
Les effets curatifs à long terme chez les patients atteints de carcinome épidermoïde de l’œsophage pris en charge par RCMI et chimiothérapie ont été influencés par le stade T, N, le stade clinique, le sexe et la localisation tumorale. En effet, les tumeurs du thorax supérieur ou de stade clinique précoce chez patients de sexe féminin avent un pronostic plus favorable.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
Abstract Hefei Light Source II (HLS-II) is a vacuum ultraviolet synchrotron light source. The HLS-II alarm system is responsible for monitoring the alarms of the process variables and distributing ...the alarm events in time. Nuisance alarms reduce the functionality, credibility and trustworthiness of the alarm system. This paper proposes a method for design alarm deadband and delay timers to remove the nuisance alarm events to the expected ratio. An optimal deadband width is calculated to reduce the alarm events while balancing the effects of reducing the occurrence number of alarm events and increasing the duration of alarm events. If the expected ratio is not met after using the optimal deadband width, the delay timers are set additionally. The Bayesian estimation approach is used to estimate the probability that the delay timers eliminate the alarm events. This method is based on statistical properties of the process variables and can effectively remove nuisance alarm events. Two examples of the HLS-II alarm system are provided to illustrate the proposed method. In the two examples, the optimal deadband removed 99.27% and 88.92% of nuisance alarms respectively.
A
bstract
Using 24.1 fb
−
1
of
e
+
e
−
collision data collected with the BESIII detector at the BEPCII collider, the Born cross sections and effective form factors of the
e
+
e
−
→
Σ
+
Σ
¯
−
reaction ...are measured. The measurements are performed at center-of-mass energies ranging from 3.510 to 4.951 GeV. No significant evidence for the decay of the charmonium(-like) states,
ψ
(3770),
ψ
(4040),
ψ
(4160),
Y
(4230),
Y
(4360),
ψ
(4415), and
Y
(4660), into a
Σ
+
Σ
¯
−
final state is observed. Consequently, upper limits for the products of the branching fractions and the electronic partial widths at the 90% confidence level are reported for these decays.
Slip/twinning activity and theoretical critical shear strengths (τmax) during room-temperature tensile deformation of as-extruded pure Mg and Mg-1wt.%Y sheets were investigated quantitatively via ...electron back-scattered diffraction (EBSD), scanning electron microscope (SEM) and first-principles calculation. Slip trace analysis results indicated the relative frequency of the active slip modes transformed from basal slip (100%) for pure Mg, to basal slip (84.8%), prismatic slip (9.7%) and pyramidal slip (5.5%) for the alloy. The proportion of grains containing twins reduced significantly from 20.5% to 5.92% with Y addition. To explain the mechanism for the enhancement of the non-basal slip activity in Mg–Y alloy, the critical resolved shear stress of basal slip and pyramidal II slip were assessed by calculating τmax. The calculated results showed that the τmax ratio of the pyramidal II slip to basal slip decreased from 13.7 to 7.5, which may be responsible for the observed enhanced activity of non-basal slip.
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Available for:
GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
10.
Cancer statistics in China, 2016 Zheng, R S; Zhang, S W; Sun, K X ...
Zhōnghuá zhŏngliú zázhì,
2023-Mar-23, Volume:
45, Issue:
3
Journal Article
Data for 2016 from cancer registries were used to estimate cancer incidence and mortality in China in 2016.
According to the quality control process of the National Central Cancer Registry, the data ...from 683 cancer registries submitted by each province were evaluated, and the data of 487 cancer registries were qualified and included in the final analysis. Age-specific incidence and mortality rates were calculated by area (urban/rural), sex, age and cancer site, combined with national population data to estimate cancer incidence and mortality in China in 2016. Chinese population census in 2000 and Segi's population were used for age-standardized incidence and mortality rates.
Total population covered by 487 cancer registries was 381 565 422 (192 628 370 in urban and 188 937 052 in rural areas). The percentages of morphologically verified (MV%) and death certificate-only cases (DCO%) accounted for 68.31% and 1.40%, respectively, and the mortality to incidence ratio was 0.61. It was estimated about 4 064 000 new cases occurred in China in 2016, with the crude incidence rate being 293.91/100 000 (the rates of males and females were 315.52/100 000 and 271.23/100 000), age-standardized incidence rates by Chinese standard population (ASIRC) and by world standard population (ASIRW) were 190.76/100 000 and 186.46/100 000, with the cumulative incidence rate (0-74 years old) being 21.42%. The crude incidence and ASIRC were 314.74/100 000 and 196.38/100 000 in urban areas, whereas in rural areas, they were 265.90/100 000 and 182.21/100 000, respectively. It was estimated about 2 413 500 cancer deaths occurred in China in 2016, the crude mortality rate was 174.55/100 000 (216.16/100 000 in males and 130.88/100 000 in females), the age-standardized mortality rates by Chinese standard population (ASMRC) and by world standard population (ASMRW) were 106.00/100 000 and 105.19/100 000, and the cumulative mortality rate (0-74 years old) was 11.85%. The crude mortality and ASMRC were 180.31/100 000 and 104.44/100 000 in urban areas, whereas in rural areas, they were 166.81/100 000 and 108.01/100 000, respectively. The most common cancer cases include lung, colorectal, stomach, liver and female breast cancers. The top five cancers accounted for about 57.27% of all cancer cases. The most common cancer deaths included lung, liver, stomach, colorectal and esophageal cancers. The top five cancers accounted for about 69.25% of all cancer deaths.
The burden of cancer shows a continuous increasing trend in China. Regional and gender differences in cancer burden are obvious. The cancer patterns still show the coexistence of cancer patterns in developed countries and developing countries. The situation of cancer prevention and control is still serious in China.
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