Objective - To investigate diagnostic methods, surgical methods and indications, early complications and short term outcome of cervical spine surgery for rheumatoid arthritis (RA). Methods - A ...nation-wide registration of rheumatoid cervical spine surgery carried out in Sweden during 1993. Results - Eighty-six (74 primary) procedures in 83 patients were reported from 11 hospitals. Pain was a more common indication for surgery than was neurologic impairment. C1-C2 instability or subluxation was present in 66/82, subaxial subluxations in 27/82 and atlantoaxial impaction in 10/82 procedures (data partly missing in one case). Indications for surgery and preoperative investigations were found to be reasonably uniform, but surgical methods and post-operative care varied between hospitals. Posterior fusion was performed in 76 patients. C1-C2 wiring with bone grafting was the most common procedure followed by occipito-cervical fusion with wires and bone cement. Subaxial cervical decompression without fusion, posterior fusion with onlay graft only, and carbon fiber grafts were used in a small number of patients. Total mortality was 5/83. The early complication rate was low, but 17 patients showed recurrent subluxation at follow-up at median 7(1-17) months. Seven of them required reoperation in the same segment. Conclusion - The variation in treatment policy and number of operated patients in the different hospitals speak in favor for centralization of cervical spine surgery in RA. New methods for C1-C2-fusion need to be evaluated.
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"A job is like a marriage in many ways, and when you lose your job you truly grieve," he said. "It can be like losing a loved one. For better or worse, your job is your identity, and when it's gone, ...how do you reinvent yourself?" "Many families can't handle it," she said. "Some lose their homes, others split up. It's a true hardship." "It's hard to know what any company will be doing in 12 months," he said. "Even for a CEO, it's hard to predict."
Twice, those on hand at the services gave Wertz a thunderous standing ovation at Friend Jim Welde's request. Welde remembered Wertz as a fun-loving guy who favored chicken wings and fast cars like ...the red Z28 Camaro he cruised around in as a young man. Hundreds of police and mourners joined family, including Wertz's widow, Tricia L., and their sons, Jared S. and Joshua A., at the graveside for a 21-gun salute, the playing of taps by a lone bugler and a rendition of "Amazing Grace" by the bagpipe and drum corps.
Removal of environmental estrogens by bacterial cell immobilization technique Ma, Cong; Dan QinauthorKey Laboratory of Urban Pollutant Conversion, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, ChinaNingbo Urban Environment Observation and Research Station-NUEORS, Chinese Academy of Sciences, Ningbo 351800, China; Qian SunauthorKey Laboratory of Urban Pollutant Conversion, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, ChinaNingbo Urban Environment Observation and Research Station-NUEORS, Chinese Academy of Sciences, Ningbo 351800, China ...
2015
Journal Article
About 25 more people signed up for the service online during the recent lockdown, apparently seeing how well it worked from other subscribers nearby, he said. ... while the contracted public safety ...officers who patrol the campus around the clock don't carry weapons or have arrest powers, they provide security and can call city police to respond quickly when needed, Smith said. Reading Area Community College Part of the debate about how to keep a campus secure but also welcoming includes whether college security officers should be armed, said Theodore Bassano, senior vice president for business services, treasurer and administrator of security at Reading Area Community College.
Bark beetles are major pests of conifer forests, and their behavior is primarily mediated via olfaction. Targeting the odorant receptors (ORs) may thus provide avenues towards improved pest control. ...Such an approach requires information on the function of ORs and their interactions with ligands, which is also essential for understanding the functional evolution of these receptors. Hence, we aimed to identify a high-quality complement of ORs from the destructive spruce bark beetle Ips typographus (Coleoptera, Curculionidae, Scolytinae) and analyze their antennal expression and phylogenetic relationships with ORs from other beetles. Using 68 biologically relevant test compounds, we next aimed to functionally characterize ecologically important ORs, using two systems for heterologous expression. Our final aim was to gain insight into the ligand-OR interaction of the functionally characterized ORs, using a combination of computational and experimental methods.
We annotated 73 ORs from an antennal transcriptome of I. typographus and report the functional characterization of two ORs (ItypOR46 and ItypOR49), which are responsive to single enantiomers of the common bark beetle pheromone compounds ipsenol and ipsdienol, respectively. Their responses and antennal expression correlate with the specificities, localizations, and/or abundances of olfactory sensory neurons detecting these enantiomers. We use homology modeling and molecular docking to predict their binding sites. Our models reveal a likely binding cleft lined with residues that previously have been shown to affect the responses of insect ORs. Within this cleft, the active ligands are predicted to specifically interact with residues Tyr84 and Thr205 in ItypOR46. The suggested importance of these residues in the activation by ipsenol is experimentally supported through site-directed mutagenesis and functional testing, and hydrogen bonding appears key in pheromone binding.
The emerging insight into ligand binding in the two characterized ItypORs has a general importance for our understanding of the molecular and functional evolution of the insect OR gene family. Due to the ecological importance of the characterized receptors and widespread use of ipsenol and ipsdienol in bark beetle chemical communication, these ORs should be evaluated for their potential use in pest control and biosensors to detect bark beetle infestations.
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"It's not the workers' fault, they keep moving the plants," he said. "It started years ago when they started moving plants down south because that was cheaper. They got away with that and now they're ...moving them out of the country." "It's just the way the economy works today, that companies can find cheaper labor in other countries," he said. "Like the famous line from 'The Godfather,' 'it's never personal, it's just business.' " "They must remain competitive," she said. "They must make a profit."
Aug. 24--The Schuylkill Valley Metro -- a $2 billion plan to link Reading and Philadelphia by light-rail passenger line -- is dead in its tracks, state officials said Wednesday. Gov. Ed Rendell ...apparently put the kibosh on the proposed line during a campaign stop Tuesday in Norristown, Montgomery County. "Schuylkill Valley Metro -- gone. That isn't going to happen," Rendell told The Associated Press. "We'll never get the funding." The proposed metro line would allow customers to ride from the outlets in Wyomissing to Center City Philadelphia. U.S. Rep. James W. Gerlach, a Chester County Republican who represents part of Berks, also disagrees with Rendell and thinks the project will still happen. Berks transportation planner Alan D. Piper said those involved with the project already knew that a $2 billion price tag was too high. Nevertheless, he also thinks the idea has enough merit for officials to try to trim those costs and find private funding. Rendell was unavailable for further comment.
Members of both Spring Township teams that Scott A. Wertz coached attended Wednesday's viewing and service at the Sovereign Center, vowing to always remember the slain officer. Welde's father, Jim ...Welde of Spring, eulogized Wertz during the service at the Sovereign Center, remembering how happy he was when the Mets team he coached won a championship this summer. Joseph McAnally of Reading stood near the railroad tracks at Seventh and Penn streets Wednesday, peering down between rows of about 1,000 police officers.McAnally's hands were on the shoulders of his son, Thomas J. MacDonald of Douglassville.McAnally said Wednesday that he took his son to the funeral to teach him about respect.Apparently, it worked."I respect cops," the 13-yearold said. "If something like that happened to me, I'd want people to come out for me, too."
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