The spectral and luminescence decay kinetics of magnesium aluminate spinel ceramics prepared by spark plasma sintering (SPS) and the starting nanopowders were studied. It was demonstrated that two ...types of luminescence in spinel ceramics can be observed after pulse e-beam excitation. The first type is due to intrinsic defects, and the second type due to Cr
3+
and Mn
2+
ions. It was shown that the luminescence decay kinetics for Cr
3+
and Mn
2+
impurity ions can be approximated by the sum of two exponents. The decay times for the Cr
3+
ion are 35 and 409 ns, for the Mn
2+
ion are 29 and 340 ns. High-temperature exposure during SPS synthesis does not lead to a change in the nearest surroundings of impurity ions. In the luminescence spectra of ceramic and powder samples the intensity ratio changes of intrinsic and impurity centers is associated with strong diffuse scattering of light for spinel nanopowders.
This paper presents measurements of production cross sections and inelastic cross sections for the following reactions: 60 GeV/c protons with C, Be, Al targets and 120 GeV/c protons with C and Be ...targets. The analysis is performed using the NA61/SHINE spectrometer at the CERN Super Proton Synchrotron. First measurements are obtained using protons at 120 GeV/c, while the results for protons at 60 GeV/c are compared with previously published measurements. These interaction cross section measurements are critical inputs for neutrino flux prediction in current and future accelerator-based long-baseline neutrino experiments.
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CMK, CTK, FMFMET, IJS, NUK, PNG, UM
Cryomilled nanocrystalline Al–7.5Mg (in wt.%) powders were consolidated by high pressure torsion (HPT). Consolidation resulted in elongated nanocrystalline grains of ∼30 nm width along the torsion ...direction and high microhardness values over 3.5 GPa at five rotations in torsion under applied pressures of 6 GPa.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
Abstract
The article presents the results of laboratory-field tests of a working body that creates an artificial pipe for irrigation of cotton with a row spacing of 60 cm from under the soil. As ...evaluation criteria, water flow distance and moisture dispersion were taken from inside the formed pipe without spilling onto the field surface. When using this working body, it was found that a pipe with dense walls was formed under the soil with low energy consumption, and water flow was observed for a long distance. Generated to the proximity of the constructed artificial pipes to the cotton roots, the water demand is met quickly and the irrigation time and water consumption are reduced.
Background.
Despite the modern therapy programs including hematopoietic stem cell transplantation, the treatment outcomes for children with acute myeloid leukemia (AML) remain unsatisfactory. The ...5‑year overall survival rate is about 70 %. The 5‑year overall survival rate for patients with relapsed and refractory AML is 2 times lower (about 35 %). The treatment failure rate in primary AML and unsatisfactory results in relapsed and refractory AML make it necessary to optimize therapy protocols.
Aim
was a long-term retro- and prospective analysis of clinical and laboratory characteristics and treatment outcomes in patients with relapsed and refractory forms of AML.
Materials and methods.
This article presents the treatment results of 54 patients from 1 to 18 years of age, with relapsed and refractory AML treated at the N. N . Blokhin National Medical Research Center of Oncology from 1997 to 2022.
Results.
A comparison of 5 different programs revealed that patients who received second remission induction with the FLA + FLA scheme had 81.8 % of response (complete or partial) achievement. Analysis of the results in achievement the second remission in patients received epigenetic agents (azacytidine, decitabine, valproic and all-trans retinoid acids) with second-line chemotherapy found that treatment response rate was 100 % (
n
= 27), in contrast to patients received only second-line chemotherapy (
n
= 27) – 81.5 % (
p
= 0.003). The best treatment results were in group of patients whose treatment included epigenetic agents and allogenic hematopoietic stem cell transplantation after second remission induction – 5‑year overall survival was 51.3 ± 9.7 %.
Conclusion.
Intensive polychemotherapy with fludarabine- and cytarabine-containing regiments with following allogeneic hematopoietic stem cell transplantation and epigenetic agents are current trend and pathogenetically based approach for relapsed and refractory pediatric AML. Probable, the definition of the role and place of targeted drugs (gemtuzumab ozogamicin) could continue the advances in treatment of such unfavorable patient group.
This work is a continuation of a cycle of studies on the generalization of geochemical information on the content of elements in the composition of rocks and oils in the area of the Ukhta anticline ...of Southern Timan region. Based on the values of yttrium (Y/Ho) and cerium anomalies (Ce sample/Ce*PAAS) established in modern sedimentary basins, the studied rocks of the Upper Devonian are divided according to the conditions of formation and transformation into predominantly hydrothermal and hydrogenous. It is shown that, depending on these conditions; zones of hydrothermal and hydrogenous mineralization with an increased content of Zn, Cu, Co, V, Mn, and Mo are formed. As a result of a comparative analysis of the content of elements in oils and the values of geochemical ratios U/Th, V/Ba, Th/Ba, As/Ba, three types of oils were identified: Yaregsky, Nizhnechutinsky high-temperature, and Nizhnechutinsky low-temperature. The values of these indicators are considered as search criteria for a certain type of oil.
EK-181 is a low-activation ferritic/martensitic steel that is an attractive candidate for in-core component materials for both fast reactors and fusion reactors. To assess the effect of ...microstructural engineering on radiation response, two variants of EK-181 were studied: one in an annealed condition and the other subject to severe plastic deformation. These specimens were irradiated with 3.5 MeV Fe self-ions up to 400 peak displacements per atom (dpa) at temperatures ranging from 400 °C to 500 °C. The deformation did not suppress swelling over the whole irradiated region. Instead, deformed samples showed higher swelling in the near-surface region. Void swelling was found to be correlated with grain boundary instability. Significant grain growth occurred when steady-state void growth started.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK, ZRSKP
A porous surface layer (a) was produced on ultrafine-grained Ni
50.8Ti
49.2 alloy (UFG NiTi) surface by sandblasting with HF/HNO
3 acid etching (AE-NiTi). This surface is bioactive and could yield ...apatite formation when soaked in simulated body fluid for 14 days (b). Osteoblast-like cells attached well after 4
h incubation (c1) and proliferated significantly after 3 days culture (c2). Such porous surface also presented lower corrosion rate and high pitting corrosion resistance in simulated body fluid compared with untreated coarse-grained NiTi (CG Ti) and UFG NiTi, as well as UFG NiTi with sandblasting (SB-NiTi) and UFG NiTi with combined sandblasting, acid etching and alkali treatment (AEAT-NiTi).
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► Irregularly rough, microporous and hierarchical porous surfaces were produced by sandblasting, acid etching and alkali treatment. ► Sandblasting with acid etching followed by alkaline treatment severely impaired the corrosion resistance. ► Sandblasting plus HF/HNO
3 solution etching increased the apatite forming ability. ► Sandblasting enhanced cell attachment and acid etching increased cell proliferation.
Bulk ultrafine-grained Ni
50.8Ti
49.2 alloy (UFG-NiTi) was successfully fabricated by equal-channel angular pressing (ECAP) technique in the present study, and to further improve its surface biocompatibility, surface modification techniques including sandblasting, acid etching and alkali treatment were employed to produce either irregularly roughened surface or microporous surface or hierarchical porous surface with bioactivity. The effect of the above surface treatments on the surface roughness, wettability, corrosion behavior, ion release, apatite forming ability and cytocompatibility of UFG-NiTi alloy were systematically investigated with the coarse-grained NiTi alloy as control. The pitting corrosion potential (
E
pit) was increased from 393
mV (SCE) to 704
mV (SCE) with sandblasting and further increased to 1539
mV (SCE) with following acid etching in HF/HNO
3 solution. All the above surface treatment increased the apatite forming ability of UFG-NiTi in varying degrees when soaked them in simulated body fluid (SBF). Meanwhile, both sandblasting and acid etching could promote the cytocompatibility for osteoblasts: sandblasting enhanced cell attachment and acid etching increased cell proliferation. The different corrosion behavior, apatite forming ability and cellular response of UFG-NiTi after different surface modifications are attributed to the topography and wettability of the resulting surface oxide layer.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
Measurements of gamma spectra allow the ratios of A (U)/A (Th) activity, the masses of U and Th, and mass ratio of U : Th to be determined for studying rocks and oils. Results demonstrate the effect ...hydrotherms have on rocks of basic and acidic composition. The values of indicators are determined to detect the presence of tuffs in rocks and pathways of oil migration.
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EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
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