Abstract
The computational cost of fast non-LTE synthesis is one of the challenges that limits the development of 2D and 3D inversion codes. It also makes the interpretation of observations of lines ...formed in the chromosphere and transition region a slow and computationally costly process, which limits the inference of the physical properties on rather small fields of view. Having access to a fast way of computing the deviation from the LTE regime through the departure coefficients could largely alleviate this problem. We propose to build and train a graph network that quickly predicts the atomic level populations without solving the non-LTE problem. We find an optimal architecture for the graph network for predicting the departure coefficients of the levels of an atom from the physical conditions of a model atmosphere. A suitable data set with a representative sample of potential model atmospheres is used for training. This data set has been computed using existing non-LTE synthesis codes. The graph network has been integrated into existing synthesis and inversion codes for the particular case of Ca
ii
. We demonstrate orders-of-magnitude gain in computing speed. We analyze the generalization capabilities of the graph network and demonstrate that it produces good predicted departure coefficients for unseen models. We implement this approach in
Hazel2
and show how the inversions nicely compare with those obtained with standard non-LTE inversion codes. Our approximate method opens up the possibility of extracting physical information from the chromosphere on large fields of view with time evolution.
Oxidative stress can play a key role in Cd-induced dysfunctions. Quercetin is a potent oxygen free radicals scavenger and a metal chelator. Our aim was to study the effect of quercetin on Cd-induced ...kidney damage and oxidative stress as well as its mechanism of action. Wistar rats were distributed in four experimental groups: control rats; Cd; quercetin and Cd
+
quercetin. Renal toxicity was evaluated by measuring urinary excretion of proteins, albumin, glucose and enzymes markers of tubular necrosis, as well as plasma concentration of creatinine. Plasma TBARS concentration and activity of antioxidant enzymes in kidney were also measured. Renal cell damage was assessed by electron microscopy. Animals that received both Cd and quercetin showed a better renal function than those receiving Cd alone. Cd-induced tubular lesions were markedly reduced in rats that also received quercetin. Cd-induced increase in plasma TBARS was prevented by the administration of quercetin. Total plasma antioxidants and renal superoxide dismutase and glutathione-reductase activities were higher in the group that received Cd and quercetin than in rats that received Cd alone. Quercetin administration does not modify the renal content or the urinary excretion of Cd. In conclusion, quercetin treatment prevents renal tubular damage and increased oxidative stress induced by chronic Cd administration, most probably throughout its antioxidant properties.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
The computational cost of fast non-LTE synthesis is one of the challenges that limits the development of 2D and 3D inversion codes. It also makes the interpretation of observations of lines formed in ...the chromosphere and transition region a slow and computationally costly process, which limits the inference of the physical properties on rather small fields of view. Having access to a fast way of computing the deviation from the LTE regime through the departure coefficients could largely alleviate this problem. We propose to build and train a graph network that quickly predicts the atomic level populations without solving the non-LTE problem. We find an optimal architecture for the graph network for predicting the departure coefficients of the levels of an atom from the physical conditions of a model atmosphere. A suitable dataset with a representative sample of potential model atmospheres is used for training. This dataset has been computed using existing non-LTE synthesis codes. The graph network has been integrated into existing synthesis and inversion codes for the particular case of \caii. We demonstrate orders of magnitude gain in computing speed. We analyze the generalization capabilities of the graph network and demonstrate that it produces good predicted departure coefficients for unseen models. We implement this approach in \hazel\ and show how the inversions nicely compare with those obtained with standard non-LTE inversion codes. Our approximate method opens up the possibility of extracting physical information from the chromosphere on large fields-of-view with time evolution.
To gather specific details about the information, communication, and treatment as regards users of hospital emergency services using a telephone survey, in order to implement improvement measures, if ...necessary.
A prospective study was conducted in two emergency departments in Salamanca. A total of 400 patients were included in the study (mean age 56.4±20.5years, 58.4% women). A telephone survey was performed with 19 items, of which 12 required responses on a Likert-type scale, with scores of 1 (very bad) to 5 (very good). The remainder of the questions allowed to answer "yes" or "no".
The treatment received by the professionals in general was evaluated positively by 86% of the patients; with 92% reporting they were respectful, 87% were treated by doctors and 71% received treatment from nurses. More than one-quarter (27.5%) did not recall receiving information from blue point staff (personnel specially trained to provide information. Statistical significance (P=.045) was found in relation to the kindness and respect shown by nurses. Most patients that were admitted to the observation area of the emergency department were not informed about the visiting hours (P=.003).
Perception of care received by patients is good, while in relation to information and communication it is evidently improvable, and could be assessed using the survey that is proposed in order to detect and use the weaknesses in these aspects of health care as implementation initiatives.
Background and ImportanceHypophosphatemia after intravenous ferric carboxymatose (FCM) is a well-documented adverse reaction. However, there is scant evidence about its prevalence among elderly ...patients with hip fracture, a complex polymedicated pluripathologic population exposed to these formulations in perioperative care.Aim and ObjectivesThe aim of this study was to identify the incidence of hypophosphatemia in patients over 65 years old treated with FCM in the context of hip surgery.Material and MethodsObservational retrospective study including all patients admitted to the Orthogeriatric Unit of a tertiary hospital from June 2023 to August 2023 for hip fracture and treated with FCM. Analytical treatment-related data were collected from electronic medical records. For descriptive analysis, categorical variables are presented as counts and percentages. Continuous variables as medians and interquartile range.Results65 patients were included (51/6578.5% women, 88±7 years old), with a median hospital stay of 13 days. The total doses used were 500 mg (69.2% of patients), 1 g (24.6%) or higher. On the gathered data are shown elevated parathormone and low cholecalciferol levels, and an altered glomerular filtration rate. Of the patients included, 28 had both pre- and post-iron administration phosphate levels measured. Among them, 21 (75%) experienced a phosphate level reduction with a mean change of -36.419.1–51.4% from their initial levels to the second measurement, mirroring the overall trend shown in the table 1. Within this group, 5 out of 28 patients (17.9%) had initial phosphate levels below 2.5 mg/dL. After iron administration, this increased up to 12 (42.9%). None of them showed any relevant clinical signs associated.Abstract 5PSQ-078 Table 1 Variable N MedianP25-P75 Before iron administration: Phosphate (mg/dL) 45 3.52.8–4.1 Hemoglobin (g/dL) 46 10.39.1–11.4 Parathormone (pg/mL) 35 86.459.2–103.5 Cholecalciferol (ng/mL) 37 23.213.6–33.9 Glomerular filtration rate (ml/min/1.73 m2) 46 5632–77.8 After iron administration: Days between iron administration and phosphate determination 42 6.53.0–9.8 Phosphate (mg/dL) 42 2.61.9–2.9 Conclusion and RelevanceBlood phosphate levels tend to decrease notably after FCM administration, suggesting a potential correlation. However, hyperparathyroidism and vitamin D deficiency are common in this population and may also influence this outcome. Phosphatemia monitoring and phosphate supplementation are measures that need to be considered to reduce possible clinical consequences, especially in elderly patients with additional risk factors.References and/or AcknowledgementsConflict of InterestNo conflict of interest.
In this work, we study the evolution of an evaporating black hole, described by the Kerr--Taub--NUT metric, which emits scalar particles. We found that allowing the black hole to radiate massless ...scalar particles increases the angular momentum loss rate while decreasing the loss rate of the NUT parameter and black hole mass. In fact, it means that angular momentum will disappear faster than the other black hole parameters (mass and NUT parameter) during the evaporation process. We also calculate the time evolution of the mass, angular momentum, and NUT parameter in order to get the evolution of the Von Neumann entropy of the black hole. We found that the entropy follows approximately the so-called Page curve, where the \(\beta\) parameter, which quantifies the amount of radiation, affects the evaporation process. Implying that high \(\beta\) values accelerate the evaporation process of a Kerr--Taub--NUT black hole.
In this article, we solve the Duffin--Kemmer--Petiau (DKP) equation in the presence of the cusp potential for spin--one particles. We derived the scattering solutions and calculated the bound states ...in terms of the Whittaker functions. We show that transmission resonances are present, as well as the particle--anti-particle bound states.
