α-Methylation of ketones is catalyzed by rhodium chloride with aqueous formaldehyde under pressures of carbon monoxide at 180 °C. Cyclohexanone and acetophenone gave mono- and dimethylated ketones in ...good yields.
α-Methylation of ketones is catalyzed by rhodium chloride with aqueous formaldehyde under pressures of carbon monoxide at 180 °C. Cyclohexanone and acetophenone gave mono- and dimethylated ketones in ...good yields.
Safe ranges for intake of food additives are expressed as ADIs (acceptable daily intake, in units of mg of additive/day/kg of body weight). An actual study of personal daily intakes of various types ...of food additives by Japanese people makes comparisons with the ADI possible, thus confirming whether intakes are within safe levels. The authors have surveyed the daily intakes of 47 types of Group A food additives (additives not normally present as constituents in foodstuffs), by age group, food group and area. The total daily intake of additives was found to be highest in adults, followed by school age children and the elderly (table 4). Intake of Group A food additives per 100g of foodstuffs was found to be highest in school age children. In all age groups, the additive ingested in greatest quantity was propylene glycol (a quality preserver), followed by sorbic acid (a preservative) (table 4, fig. 1). Intake among adults and school age children was high in group 4 (seafood and meat) and group 2 (cereals). A different intake pattern was found among the elderly, however. In all age groups, intake in group 4 was high due to the sorbic acid, while intake by adults and school age children was high in group 2 due to proplylene glycol (tables 5-, figs 2-4). In all age groups, food additive intake was higher in Western Japan than in Eastern and Central regions, due to a higher intake of propylene glycol in the West (table, 8, fig 5). The highest level of consumption relative to of the ADI was found in school age children's intake of polypropylene glycol, at 5.9%, followed by polypropylene glycol in adults (4.0%), and sorbic acid in schoolchildren (3.4%). However all of these levels were low relative to the ADI (table 9).
B-5-4 Structure of Lampterol(Terpenoids) FUKUOKA, YOHEI; Ichihara, Akitami; Matsumoto, Takeshi ...
International Symposium on the Chemistry of Natural Products,
1964
Journal Article
PDF
