Support vector machine (SVM) is introduced as a method for the classification of proteins into functionally distinguished classes. Studies are conducted on a number of protein classes including ...RNA-binding proteins; protein homodimers, proteins responsible for drug absorption, proteins involved in drug distribution and excretion, and drug metabolizing enzymes. Testing accuracy for the classification of these protein classes is found to be in the range of 84–96%. This suggests the usefulness of SVM in the classification of protein functional classes and its potential application in protein function prediction.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
Powdery mildew, caused by Blumeria graminis f. sp. tritici, is a widespread wheat disease in China. Identification of race-specific genes and adult plant resistance (APR) is of major importance in ...breeding for an efficient genetic control strategy. The objectives of this study were to (i) identify genes that confer seedling resistance to powdery mildew in Chinese bread wheat cultivars and introductions used by breeding programs in China and (ii) evaluate their APR in the field. The results showed that (i) 98 of 192 tested wheat cultivars and lines appear to have one or more resistance genes to powdery mildew; (ii) Pm8 and Pm4b are the most common resistance genes in Chinese wheat cultivars, whereas Pm8 and Pm3d are present most frequently in wheat cultivars introduced from CIMMYT, the United States, and European countries; (iii) genotypes carrying Pm1, Pm3e, Pm5, and Pm7 were susceptible, whereas those carrying Pm12, Pm16, and Pm20 were highly resistant to almost all isolates of B. graminis f. sp. tritici tested; and (iv) 22 genotypes expressed APR. Our data showed that the area under the disease progress curve, maximum disease severity on the penultimate leaf, and the disease index are good indicators of the degree of APR in the field. It may be a good choice to combine major resistance genes and APR genes in wheat breeding to obtain effective resistance to powdery mildew.
By DC magnetron sputtering,the Ni films of 600 nm thickness were successfully deposited on BF33 glass substrates.Then annealing at different temperature from 150 to 450°C and different holding time ...from 3 to 6 hours under vacuum conditions using bonding machine.The surface morphology and structure of Ni films were analyzed by scanning electron microscopy(SEM), films surface roughness and resistivity were investigated by atomic force microscope(AFM) and four-probe tester respectively. The results show that the annealing process contributes to the refinement of the grains.And the films roughness reaches the best level at the annealing temperature of 300 ° C and the roughness data with holding time of 6h is 0.678 nm. Above all,As the annealing temperature increases, the films resistivity decreases significantly.The surface roughness decreases and the resistivity gradually decreases.
Structural investigations by using high-resolution transmission electron microscopy (HRTEM) and selected area electron diffraction (SAED) of silver nanodisks with different sizes are presented. The ...disks have a face centered cubic (fcc) crystal structure and their flat surfaces are (111). Stacking faults parallel to the (111) planes are frequently observed for the nanodisks. A unique (111) stacking fault model which is parallel to the flat (111) disk surface has been proposed to explain the observed 1/3{422} forbidden reflections in 111 SAED pattern and the corresponding 3×{422} supperlattice fringes in the 111 HRTEM image. It is suggested that the presence of the stacking faults may be the key in the formation and growth of the disk morphology. This study may provide an insight to synthetically controlling particle shape and size through defect engineering.
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IJS, KILJ, NUK, PNG, UL, UM
Highlights • AMPAR, EAAT2 and EAAT3 might be involved in prenatal stress induced offspring depression. • Prenatal stress caused behavioural despair in TST of juvenile rat offspring. • Prenatal stress ...reduced EAAT2 and EAAT3 mRNA levels in the hippocampus, striatum and frontal cortex of juvenile rat offspring. • Prenatal stress differently changed pGluR1 expression in the hippocampus and frontal cortex in juvenile rat offspring.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
Copper–chlorine thermochemical cycles for hydrogen production are very promising water splitting cycles. In this paper, different types of copper–chlorine cycles with various numbers of steps are ...compared. The factors that determine the number and effective grouping of steps are analyzed. It is found that the water requirement in the hydrolysis step is affected by a combination of drying and hydrolysis steps. It is also found that hydrogen can be produced either from electrolysis of cuprous chloride, or from chlorination of copper by hydrogen chloride, which indicates a potential combination of disproportionation and chlorination steps. The major engineering advantages and disadvantages of these cycle variations with different amounts of steps will be analyzed and discussed.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
Abstract Current antimicrobial strategies have mostly been developed to manage infections due to planktonic cells. However, microbes in their nature state will tend to exist by attaching to and ...growing on living and inanimate surfaces that result in the formation of biofilms. Conventional therapies for treating biofilm-related infections are likely to be insufficient due to the lower susceptibility of microbes that are embedded in the biofilm matrix. In this study, we report the development of biodegradable hydrogels from vitamin E-functionalized polycarbonates for antimicrobial applications. These hydrogels were formed by incorporating positively-charged polycarbonates containing propyl and benzyl side chains with vitamin E moiety into physically cross-linked networks of “ABA”-type polycarbonate and poly(ethylene glycol) triblock copolymers. Investigations of the mechanical properties of the hydrogels showed that the G′ values ranged from 1400 to 1600 Pa and the presence of cationic polycarbonate did not affect the stiffness of the hydrogels. Shear-thinning behavior was observed as the hydrogels displayed high viscosity at low shear rates that dramatically decreased as the shear rate increased. In vitro antimicrobial studies revealed that the more hydrophobic VE/BnCl(1:30)-loaded hydrogels generally exhibited better antimicrobial/antifungal effects compared to the VE/PrBr(1:30) counterpart as lower minimum biocidal concentrations (MBC) were observed in Staphylococcus aureus (Gram-positive), Escherichia coli (Gram-negative) and Candida albicans (fungus) (156.2, 312.5, 312.5 mg/L for VE/BnCl(1:30) and 312.5, 2500 and 625 mg/L for VE/PrBr(1:30) respectively). Similar trends were observed for the treatment of biofilms where VE/BnCl(1:30)-loaded hydrogels displayed better efficiency with regards to eradication of biomass and reduction of microbe viability of the biofilms. Furthermore, a high degree of synergistic antimicrobial effects was also observed through the co-delivery of antimicrobial polycarbonates with a conventionally-used antifungal agent, fluconazole. These hydrogels also displayed excellent compatibility with human dermal fibroblasts with cell viability >80% after treatment with hydrogels loaded with cationic polymers and/or fluconazole at minimum biocidal concentrations (MBC).
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
Sensor networks are a key technological and economic driver for global industries in the near future, with applications in health care, environmental monitoring, infrastructure monitoring, national ...security, and more. Developing technologies for self‐powered nanosensors is vitally important. This paper gives a brief summary about recent progress in the area, describing nanogenerators that are capable of providing sustainable self‐sufficient micro/nanopower sources for future sensor networks.
Sensor networks are a key technological and economic driver for global industries in the near future, with applications in health care, environmental monitoring, infrastructure monitoring, national security, and more. This paper introduces a technology that is capable of providing sustainable self‐sufficient micro/nano‐power sources for future sensor networks.
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BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SAZU, SBCE, SBMB, UL, UM, UPUK
•The impact of natural polymer derivatives (NPD) on sheet erosion was tested.•NPD can reduce runoff and erosion effectively.•NPD can significantly improved the shear strength and the composition of ...surface aggregates of the soil.
Macromolecular polymers can effectively improve soil structure, increase soil penetration and control runoff and erosion on hillslopes. Simulated rainfall experiments on a bare soil investigated the impact of natural polymer derivatives (NPD) on soil properties and the characteristics of runoff and sediment yield of sheet erosion on experimental loessial hillslopes. A control (without NPD) and three concentrations of polymers (1, 3 and 5g/m2) were tested at rainfall intensities of 1, 1.5 and 2mm/min and a slope gradient of 15°. NPD effectively altered the onset, volume and sediment content of the runoff. Higher concentrations of NPD provided earlier onsets, lower depth and lower sediment contents of the runoff. Compared with control, cumulative runoffs decreased by 49–68%, 61–70% and 69–79% at concentrations of 1, 3 and 5g/m2 NPD, respectively, while cumulative erosion modulus decreased by 31–37%, 39–47%, 56–61%, respectively. Additionally, NPDs significantly increased the shear strength and the composition of aggregates from soil surface. Shear strength was 2.71, 3.24 and 4.01 times higher at 1, 3 and 5g/m2, respectively, than in the controls. The percent mass of aggregates >0.25mm increased to 52.5%, 62.65% and 73.0% from 8.9% in the control at the three respective concentrations. More research is needed to confirm the utility of NPDs in helping to control sheet erosion.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
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