Abstract Background The arterial switch operation (ASO) is the preferred procedure for children with dextro-transposition of the great arteries (d-TGA) or Taussig-Bing anomaly (TBA). Both short and ...long-term outcome of ASO are excellent, but coronary artery stenoses are reported as a common long-term complication. It has been hypothesized that these may result in sudden cardiac death late after ASO. Methods A systematic search of PubMed and EMBASE was conducted to evaluate sudden cardiac death due to coronary complications late after ASO. Data on patients surviving ≥5 years post-ASO were collected from selected studies, corrected for duplicate data and analyzed. Results After duplicate data correction 52 studies remained for data analysis. Among the 8,798 survivors with follow-up, 27 patients died ≥5 years post-ASO (0.3%). Of these patiens, ten were known with relevant residual lesions. Five late deaths were sudden, possibly from a cardiac cause. None of the late sudden deaths were confirmed to be coronary related. Conclusions Sudden cardiac death in asymptomatic patients as a result of coronary artery stenosis or occlusion is extremely rare, with five possible cases and no proven cases of coronary artery-related SCD in 8,798 patients with 66,450 patient follow-up years. Therefore, routine coronary imaging of asymptomatic, single-stage ASO patients is not justified.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK, ZRSKP
Pitt‐Hopkins syndrome (PTHS) is a rare neurodevelopmental disorder caused by mutations of the transcription factor 4 (Tcf4) gene. Individuals with PTHS often suffer from severe abdominal bloating and ...constipation. In this short communication, we discuss two individuals with PTHS who died unexpectedly due to gastrointestinal complications. We aim to increase awareness among healthcare professionals who care for individuals with PTHS, to ensure adequate screening and management of gastrointestinal symptoms in this population. Moreover, we discuss how fatal gastrointestinal complications may be related to PTHS and provide an overview of the literature.
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BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SBCE, SBMB, UL, UM, UPUK
ABSTRACT Introduction To choose a suitable prosthesis, clients need to experience both the weight and the control of a prosthesis. A few years ago, De Hoogstraat Rehabilitation Center developed the ...Xperience Prosthesis for children and adults with a transradial congenital or acquired limb deficiency. Because of the positive effects, we developed a reusable test prosthesis for the transhumeral level. Xperience Prosthesis Transhumeral is an innovative test prosthesis and an essential tool in managing expectations when providing clients with a suitable upper-limb prosthesis. Xperience Prosthesis Transhumeral is a 3D-printed, reusable adjustable socket system with a passive elbow unit and the possibility to fit and experience myoelectric, static, and passive terminal devices. Conclusions Xperience Prosthesis Transhumeral is a practical and easy-to-handle tool for professionals. For clients, this tool is a unique way to experience the weight, function, and control of a prosthesis before making a final choice. Clinical Relevance Using Xperience Prosthesis Transhumeral in an expert rehabilitation center for upper-limb clients guides professionals to choose the right prosthesis with the client.
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