Extreme droughts are expected to increase in frequency and severity in many regions of the world, threatening multiple ecosystem services provided by forests. Effective strategies to adapt forests to ...such droughts require comprehensive information on the effects and importance of the factors influencing forest resistance and resilience. We used a unique combination of inventory and dendrochronological data from a long‐term (>30 years) silvicultural experiment in mixed silver fir and Norway spruce mountain forests along a temperature and precipitation gradient in southwestern Germany. We aimed at examining the mechanisms and forest stand characteristics underpinning the resistance and resilience to past mild and severe droughts. We found that (i) fir benefited from mild droughts and showed higher resistance (i.e., lower growth loss during drought) and resilience (i.e., faster return to pre‐drought growth levels) than spruce to all droughts; (ii) species identity determined mild drought responses while species interactions and management‐related factors strongly influenced the responses to severe droughts; (iii) intraspecific and interspecific interactions had contrasting effects on the two species, with spruce being less resistant to severe droughts when exposed to interaction with fir and beech; (iv) higher values of residual stand basal area following thinning were associated with lower resistance and resilience to severe droughts; and (v) larger trees were resilient to mild drought events but highly vulnerable to severe droughts. Our study provides an analytical approach for examining the effects of different factors on individual tree‐ and stand‐level drought response. The forests investigated here were to a certain extent resilient to mild droughts, and even benefited from such conditions, but were strongly affected by severe droughts. Lastly, negative effects of severe droughts can be reduced through modifying species composition, tree size distribution and stand density in mixed silver fir‐Norway spruce forests.
We examined mechanisms and stand characteristics underpinning the growth resistance (Rt), recovery (Rc) and resilience (Rs) to past mild and severe droughts in mixed silver fir and Norway spruce mountain forests in southwestern Germany. We found that the forests investigated were to a certain extent resilient to mild droughts, and even benefited from such conditions, but were strongly affected by severe droughts (especially those stands with higher residual basal area and larger trees). Lastly, negative effects of severe droughts can be reduced through modifying species composition, tree size distribution and stand density in mixed silver fir‐Norway spruce forests.
Full text
Available for:
BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SAZU, SBCE, SBMB, UL, UM, UPUK
Endoscopic variceal ligation plus beta‐blockers (EVL+BB) is currently recommended for variceal rebleeding prophylaxis, a recommendation that extends to all patients with cirrhosis with previous ...variceal bleeding irrespective of prognostic stage. Individualizing patient care is relevant, and in published studies on variceal rebleeding prophylaxis, there is a lack of information regarding response to therapy by prognostic stage. This study aimed at comparing EVL plus BB with monotherapy (EVL or BB) on all‐source rebleeding and mortality in patients with cirrhosis and previous variceal bleeding stratified by cirrhosis severity (Child A versus B/C) by means of individual time‐to‐event patient data meta‐analysis from randomized controlled trials. The study used individual data on 389 patients from three trials comparing EVL plus BB versus BB and 416 patients from four trials comparing EVL plus BB versus EVL. Compared with BB alone, EVL plus BB reduced overall rebleeding in Child A (incidence rate ratio 0.40; 95% confidence interval, 0.18‐0.89; P = 0.025) but not in Child B/C, without differences in mortality. The effect of EVL on rebleeding was different according to Child (P for interaction <0.001). Conversely, compared with EVL, EVL plus BB reduced rebleeding in both Child A and B/C, with a significant reduction in mortality in Child B/C (incidence rate ratio 0.46; 95% confidence interval, 0.25‐0.85; P = 0.013). Conclusion: Outcomes of therapies to prevent variceal rebleeding differ depending on cirrhosis severity: in patients with preserved liver function (Child A), combination therapy is recommended because it is more effective in preventing rebleeding, without modifying survival, while in patients with advanced liver failure (Child B/C), EVL alone carries an increased risk of rebleeding and death compared with combination therapy, underlining that BB is the key element of combination therapy. (Hepatology 2017;66:1219‐1231).
Full text
Available for:
BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SAZU, SBCE, SBMB, UL, UM, UPUK
Solutans were among the most enigmatic pre-radial and asymmetric echinoderms. A new species Dehmicystis ariasi sp. nov. is described from the upper part of the Llagarinos Formation, lower Ludlow ...(Silurian) of Northwest Spain. This is the first solutan formally described from Iberia and the first from the Silurian worldwide. Dehmicystis was previously known based on a small number of poorly preserved specimens from the Emsian, Lower Devonian Hunsruck Slate of Germany. New observations based on the newly studied material suggest that Dehmicystis displayed a feeding appendage facing towards the substrate, and the periproct on the opposite face of the theca. Comparisons with other solutans and new data suggest that Dehmicystis was a detritus feeder that moved over the substrate capturing organic particles from the sediment with a single feeding arm. Key words: Echinodermata, Soluta, pre-radial, asymmetric, Rhuddanian, Silurian, Spain.
Nowadays, smartphones have become ubiquitous and one of the main communication resources for human beings. Their widespread adoption was due to the huge technological progress and to the development ...of multiple useful applications. Their characteristics have also experienced a substantial improvement as they now integrate multiple sensors able to convert the smartphone into a flexible and multi-purpose sensing unit. The combined use of multiple smartphones endowed with several types of sensors gives the possibility to monitor a certain area with fine spatial and temporal granularity, a procedure typically known as crowdsensing. In this paper, we propose using smartphones as environmental noise-sensing units. For this purpose, we focus our study on the sound capture and processing procedure, analyzing the impact of different noise calculation algorithms, as well as in determining their accuracy when compared to a professional noise measurement unit. We analyze different candidate algorithms using different types of smartphones, and we study the most adequate time period and sampling strategy to optimize the data-gathering process. In addition, we perform an experimental study comparing our approach with the results obtained using a professional device. Experimental results show that, if the smartphone application is well tuned, it is possible to measure noise levels with a accuracy degree comparable to professional devices for the entire dynamic range typically supported by microphones embedded in smartphones, i.e., 35-95 dB.
Full text
Available for:
IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
Summary
Acremonium strictum elicitor subtilisin (AsES) is a 34‐kDa serine‐protease secreted by the strawberry fungal pathogen A. strictum. On AsES perception, a set of defence reactions is induced, ...both locally and systemically, in a wide variety of plant species and against pathogens of alternative lifestyles. However, it is not clear whether AsES proteolytic activity is required for triggering a defence response or if the protein itself acts as an elicitor. To investigate the necessity of the protease activity to activate the defence response, AsES coding sequences of the wild‐type gene and a mutant on the active site (S226A) were cloned and expressed in Escherichia coli. Our data show that pretreatment of Arabidopsis plants with inactive proteins, i.e. inhibited with phenylmethylsulphonyl fluoride (PMSF) and mutant, resulted in an increased systemic resistance to Botrytis cinerea and expression of defence‐related genes in a temporal manner that mimics the effect already reported for the native AsES protein. The data presented in this study indicate that the defence‐eliciting property exhibited by AsES is not associated with its proteolytic activity. Moreover, the enhanced expression of some immune marker genes, seedling growth inhibition and the involvement of the co‐receptor BAK1 observed in plants treated with AsES suggests that AsES is being recognized as a pathogen‐associated molecular pattern by a leucine‐rich repeat receptor. The understanding of the mechanism of action of AsES will contribute to the development of new breeding strategies to confer durable resistance in plants.
Full text
Available for:
BFBNIB, DOBA, FZAB, GIS, IJS, IZUM, KILJ, NLZOH, NUK, OILJ, PILJ, PNG, SAZU, SBCE, SBMB, UILJ, UKNU, UL, UM, UPUK
The chili pepper is a very important plant used worldwide as a vegetable, as a spice, and as an external medicine. In this work, eight different varieties of Capsicum annuum L. have been ...characterized by their capsaicinoids content. The chili pepper fruits were cultivated in the Comarca Lagunera region in North of Mexico. The qualitative and quantitative determination of the major and minor capsaicinoids; alkaloids responsible for the pungency level, has been performed by a validated chromatographic procedure (HPLC-DAD) after a preliminary drying step and an opportune extraction procedure. Concentrations of total capsaicinoids varied from a not detectable value for Bell pepper to 31.84 mg g(-1) dried weight for Chiltepín. Samples were obtained from plants grown in experimental field and in greenhouse without temperature control, in order to evaluate temperature effect. Analysis of the two principal capsaicinoids in fruits showed that the amount of dihydrocapsaicin was always higher than capsaicin. In addition, our results showed that the content of total capsaicinoids for the varieties Serrano, Puya, Ancho, Guajillo and Bell pepper were increased with high temperature, while the content of total capsaicinoids and Scoville heat units (SHU) for the varieties De árbol and Jalapeño decreased. However, the pungency values found in this study were higher for all varieties analyzed than in other studies.
Full text
Available for:
IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
As the number of potential applications for Unmanned Aerial Vehicles (UAVs) keeps rising steadily, the chances that these devices get close to each other during their flights also increases, causing ...concerns regarding potential collisions. This paper proposed the Mission Based Collision Avoidance Protocol (MBCAP), a novel UAV collision avoidance protocol applicable to all types of multicopters flying autonomously. It relies on wireless communications in order to detect nearby UAVs, and to negotiate the procedure to avoid any potential collision. Experimental and simulation results demonstrated the validity and effectiveness of the proposed solution, which typically introduces a small overhead in the range of 15 to 42 s for each risky situation successfully handled.
Full text
Available for:
IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
Noise pollution is an emerging and challenging problem of all large metropolitan areas, affecting the health of citizens in multiple ways. Therefore, obtaining a detailed and real-time map of noise ...in cities becomes of the utmost importance for authorities to take preventive measures. Until now, these measurements were limited to occasional sampling made by specialized companies, that mainly focus on major roads. In this paper, we propose an alternative approach to this problem based on crowdsensing. Our proposed architecture empowers participating citizens by allowing them to seamlessly, and based on their context, sample the noise in their surrounding environment. This allows us to provide a global and detailed view of noise levels around the city, including places traditionally not monitored due to poor accessibility, even while using their vehicles. In the paper, we detail how the different relevant issues in our architecture, i.e., smartphone calibration, measurement adequacy, server design, and client⁻server interaction, were solved, and we have validated them in real scenarios to illustrate the potential of the solution achieved.
Full text
Available for:
IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
Fog computing, an extension of the Cloud Computing paradigm where routers themselves may provide the virtualisation infrastructure, aims at achieving fluidity when distributing in-network functions, ...in addition to allowing fast and scalable processing, and exchange of information. In this paper we present a fog computing architecture based on a "content island" which interconnects sets of "things" to exchange and process data among themselves or with other content islands. We then present a use case that focuses on a smartphone-based forward collision warning application for a connected vehicle scenario. This application makes use of the optical sensor of smartphones to estimate the distance between the device itself and other vehicles in its field of view. The vehicle travelling directly ahead is identified relying on the information from the GPS, camera, and inter-island communication. Warnings are generated at both content islands, if the driver does not maintain a predefined safe distance towards the vehicle ahead. Experiments performed with the application show that with the developed method, we are able to estimate the distance between vehicles, and the inter-island communication has a very low overhead, resulting in improved performance. On comparing our proposed solution based on edge/fog computing with a cloud-based api, it was observed that our solution outperformed the cloud-based api, thus making us optimistic of the utility of the proposed architecture.
Full text
Available for:
IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
Vitamin A signals play critical roles during embryonic development. In particular, heart morphogenesis depends on vitamin A signals mediated by the retinoid X receptor α (RXRα), as the systemic ...mutation of this receptor results in thinning of the myocardium and embryonic lethality. However, the molecular and cellular mechanisms controlled by RXRα signaling in this process are unclear, because a myocardium-restricted RXRα mutation does not perturb heart morphogenesis. Here, we analyze a series of tissue-restricted mutations of the RXRα gene in the cardiac neural crest, endothelial, and epicardial lineages, and we show that RXRα signaling in the epicardium is required for proper cardiac morphogenesis. Moreover, we detect an additional phenotype of defective coronary arteriogenesis associated with RXRa deficiency and identify a retinoid-dependent Wnt signaling pathway that cooperates in epicardial epithelial-to-mesenchymal transformation. Coronary Vessels | Epicardium | Retinoids | WNT | FGF
Full text
Available for:
BFBNIB, NMLJ, NUK, PNG, SAZU, UL, UM, UPUK
PDF
